Pseudomonas aeruginosa defense systems against microbicidal oxidants

The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation

(2017) Jan-Ulrik Dahl et al.   Nature Microbiology

Reactive Oxygen Species and Neutrophil Function

(2016) Christine C. Winterbourn et al.   Annual Review of Biochemistry

Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages

(2016) Dominic T. Love et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of Organic Hydroperoxide Stress Response by Two OhrR Homologs in Pseudomonas aeruginosa

(2016) Sopapan Atichartpongkul et al.   PLoS One

Oxidative stress protection by polyphosphate—new roles for an old player

(2015) Michael J Gray et al.   CURRENT OPINION IN MICROBIOLOGY

Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health

(2015) Joshua D. Chandler et al.   FREE RADICAL RESEARCH

Protein Quality Control under Oxidative Stress Conditions

(2015) Jan-Ulrik Dahl et al.   JOURNAL OF MOLECULAR BIOLOGY

Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange

(2015) Laura R Hmelo et al.   Nature Protocols

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Polyphosphate Is a Primordial Chaperone

(2014) Michael J. Gray et al.   MOLECULAR CELL

Activation of RidA chaperone function by N-chlorination

(2014) Alexandra Müller et al.   Nature Communications

Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense

(2013) Joshua D. Chandler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NemR Is a Bleach-sensing Transcription Factor

(2013) Michael J. Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RclR Protein Is a Reactive Chlorine-specific Transcription Factor inEscherichia coli

(2013) Benjamin W. Parker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates

(2012) Tessa J. Barrett et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactions and reactivity of myeloperoxidase-derived oxidants: Differential biological effects of hypochlorous and hypothiocyanous acids

(2012) David I. Pattison et al.   FREE RADICAL RESEARCH

MexT Functions as a Redox-Responsive Regulator Modulating Disulfide Stress Resistance in Pseudomonas aeruginosa

(2012) E. Fargier et al.   JOURNAL OF BACTERIOLOGY

Identification of a Hypochlorite-specific Transcription Factor fromEscherichia coli

(2012) Katharina M. Gebendorfer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cystic fibrosis: a mucosal immunodeficiency syndrome

(2012) Taylor Sitarik Cohen et al.   NATURE MEDICINE

Global regulation of gene expression by OxyR in an important human opportunistic pathogen

(2012) Qing Wei et al.   NUCLEIC ACIDS RESEARCH

Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

(2011) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

Hypothiocyanous Acid: Benign or Deadly?

(2011) Tessa J. Barrett et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

(2011) Daniel Lorentzen et al.   FREE RADICAL BIOLOGY AND MEDICINE

S-Bacillithiolation Protects Against Hypochlorite Stress inBacillus subtilisas Revealed by Transcriptomics and Redox Proteomics

(2011) Bui Khanh Chi et al.   MOLECULAR & CELLULAR PROTEOMICS

Comparative Transcriptomic and Phenotypic Analysis of the Responses of Bacillus cereus to Various Disinfectant Treatments

(2010) M. Ceragioli et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

(2010) Michael J. Davies   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

(2009) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms

(2009) P. D. Lister et al.   CLINICAL MICROBIOLOGY REVIEWS

Quantification of protein modification by oxidants

(2009) Clare L. Hawkins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inorganic Chemistry of Defensive Peroxidases in the Human Oral Cavity

(2009) M. T. Ashby   JOURNAL OF DENTAL RESEARCH

Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications

(2008) Michael J. Davies et al.   ANTIOXIDANTS & REDOX SIGNALING

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding

(2008) J. Winter et al.   CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology