Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health

Glutaredoxin-1 AttenuatesS-Glutathionylation of the Death Receptor Fas and Decreases Resolution ofPseudomonas aeruginosaPneumonia

(2014) Vikas Anathy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach

(2014) Corin Storkey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides

(2014) Tracey B. Kajer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: Critical protective actions of ascorbate and thiocyanate

(2014) Martin D. Rees et al.   FREE RADICAL BIOLOGY AND MEDICINE

High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

(2014) P. E. Nedoboy et al.   FREE RADICAL RESEARCH

Inactivation of Human Salivary Glutathione Transferase P1-1 by Hypothiocyanite: A Post-Translational Control System in Search of a Role

(2014) Raffaele Fabrini et al.   PLoS One

Inhalation Treatment with Glutathione in Patients with Cystic Fibrosis. A Randomized Clinical Trial

(2013) Matthias Griese et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction

(2013) Jihan Talib et al.   BIOCHEMICAL JOURNAL

What is the total number of protein molecules per cell volume? A call to rethink some published values

(2013) Ron Milo   BIOESSAYS

Nebulized thiocyanate improves lung infection outcomes in mice

(2013) J D Chandler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells

(2013) Mitchell M. Lloyd et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ceruloplasmin Is an Endogenous Inhibitor of Myeloperoxidase

(2013) Anna L. P. Chapman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Metabolism of Hypothiocyanous Acid by Mammalian Thioredoxin Reductase Promotes Lung Innate Immunity and Antioxidant Defense

(2013) Joshua D. Chandler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Redox Biochemistry of Protein Sulfenylation and Sulfinylation

(2013) Mauro Lo Conte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effects of perchlorate, nitrate and thiocyanate on free thyroxine for potentially sensitive subpopulations of the 2001–2002 and 2007–2008 National Health and Nutrition Examination Surveys

(2013) Mina Suh et al.   Journal of Exposure Science and Environmental Epidemiology

Selenocysteine in Thiol/Disulfide-Like Exchange Reactions

(2012) Robert J. Hondal et al.   ANTIOXIDANTS & REDOX SIGNALING

THIOCYANATE: A potentially useful therapeutic agent with host defense and antioxidant properties

(2012) Joshua D. Chandler et al.   BIOCHEMICAL PHARMACOLOGY

High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine

(2012) Jihan Talib et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of innate immunity by NADPH oxidase

(2012) Brahm H. Segal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells

(2012) Martin D. Rees et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vascular peroxidase 1 catalyzes the formation of hypohalous acids: Characterization of its substrate specificity and enzymatic properties

(2012) Hong Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactions and reactivity of myeloperoxidase-derived oxidants: Differential biological effects of hypochlorous and hypothiocyanous acids

(2012) David I. Pattison et al.   FREE RADICAL RESEARCH

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Environmental Perchlorate and Thiocyanate Exposures and Infant Serum Thyroid Function

(2012) Angela M. Leung et al.   THYROID

Hydrogen Sulfide and Cell Signaling

(2011) Ling Li et al.   Annual Review of Pharmacology and Toxicology

Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage

(2011) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

Factors Affecting Protein Thiol Reactivity and Specificity in Peroxide Reduction

(2011) Gerardo Ferrer-Sueta et al.   CHEMICAL RESEARCH IN TOXICOLOGY

High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

(2011) Philip E. Morgan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

(2011) Daniel Lorentzen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Serine Proteases Degrade Airway Mucins in Cystic Fibrosis

(2011) Markus O. Henke et al.   INFECTION AND IMMUNITY

Urate as a Physiological Substrate for Myeloperoxidase

(2011) Flavia C. Meotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iodine Status and Thyroid Function of Boston-Area Vegetarians and Vegans

(2011) Angela M. Leung et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Macropinocytosis of Extracellular Glutathione Ameliorates Tumor Necrosis Factor α Release in Activated Macrophages

(2011) Neal S. Gould et al.   PLoS One

Differing views of the role of selenium in thioredoxin reductase

(2010) Robert J. Hondal et al.   AMINO ACIDS

The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

(2010) Amanda E. Lane et al.   BIOCHEMICAL JOURNAL

Small Molecular, Macromolecular, and Cellular Chloramines React with Thiocyanate To Give the Human Defense Factor Hypothiocyanite

(2010) Bheki A. Xulu et al.   BIOCHEMISTRY

Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine?

(2010) Elias S.J. Arnér   EXPERIMENTAL CELL RESEARCH

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

(2010) Eline Thomson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypothiocyanous acid is a potent inhibitor of apoptosis and caspase 3 activation in endothelial cells

(2010) Stephanie M. Bozonet et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

(2009) Ojia Skaff et al.   BIOCHEMICAL JOURNAL

Reactive Sulfur Species: Kinetics and Mechanism of the Reaction of Hypothiocyanous Acid with Cyanide To Give Dicyanosulfide in Aqueous Solution

(2009) Kelemu Lemma et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Kinetics and Mechanisms of the Reaction of Hypothiocyanous Acid with 5-Thio-2-nitrobenzoic Acid and Reduced Glutathione

(2009) Péter Nagy et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative epithelial host defense is regulated by infectious and inflammatory stimuli

(2009) Monica Valencia Gattas et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion

(2009) Mary Abigail S. Garcia et al.   JOURNAL OF CLINICAL INVESTIGATION

Estimated Dietary Intake of Thiocyanate from Brassicaceae Family in Korean Diet

(2009) Hyejung Han et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases

(2009) Y. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

(2008) Mitchell M. Lloyd et al.   BIOCHEMICAL JOURNAL

Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

(2008) Clare L. Hawkins et al.   BIOCHEMICAL JOURNAL

Thiocyanate concentration in saliva of cystic fibrosis patients.

(2008) Łukasz Minarowski et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Thiol chemistry and specificity in redox signaling

(2008) Christine C. Winterbourn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenoproteins

(2008) Jun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The peroxidase-cyclooxygenase superfamily: Reconstructed evolution of critical enzymes of the innate immune system

(2008) Marcel Zamocky et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Comparison of Mainstream and Sidestream Marijuana and Tobacco Cigarette Smoke Produced under Two Machine Smoking Conditions

(2007) David Moir et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology

(2007) Melissa Kemp et al.   FREE RADICAL BIOLOGY AND MEDICINE