Molecular Imaging in Synthetic Biology, and Synthetic Biology in Molecular Imaging

Molecular Engineering of Acoustic Protein Nanostructures

(2016) Anupama Lakshmanan et al.   ACS Nano

A Genetically Encoded β-Lactamase Reporter for Ultrasensitive129Xe NMR in Mammalian Cells

(2016) Yanfei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

(2016) Kole T. Roybal et al.   CELL

Synchronized cycles of bacterial lysis for in vivo delivery

(2016) M. Omar Din et al.   NATURE

MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter

(2016) Franz Schilling et al.   NATURE BIOTECHNOLOGY

DNA writers attract investors

(2016) Justin Petrone   NATURE BIOTECHNOLOGY

Tunable thermal bioswitches for in vivo control of microbial therapeutics

(2016) Dan I Piraner et al.   Nature Chemical Biology

Prospects for gene-engineered T cell immunotherapy for solid cancers

(2016) Christopher A Klebanoff et al.   NATURE MEDICINE

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Molecular imaging with engineered physiology

(2016) Mitul Desai et al.   Nature Communications

Non-invasive imaging using reporter genes altering cellular water permeability

(2016) Arnab Mukherjee et al.   Nature Communications

Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators

(2016) X Luís Deán-Ben et al.   Light-Science & Applications

Molecular Engineering of Nonmetallic Biosensors for CEST MRI

(2015) Amnon Bar-Shir et al.   ACS Chemical Biology

Advances in using MRI probes and sensors for in vivo cell tracking as applied to regenerative medicine

(2015) A. K. Srivastava et al.   Disease Models & Mechanisms

Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging

(2015) Claudia Errico et al.   NATURE

Programmed synthesis of three-dimensional tissues

(2015) Michael E Todhunter et al.   NATURE METHODS

Advances in real-time multispectral optoacoustic imaging and its applications

(2015) Adrian Taruttis et al.   Nature Photonics

Synthetic biology devices for in vitro and in vivo diagnostics

(2015) Shimyn Slomovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Programmable probiotics for detection of cancer in urine

(2015) Tal Danino et al.   Science Translational Medicine

Violacein as a genetically-controlled, enzymatically amplified and photobleaching-resistant chromophore for optoacoustic bacterial imaging

(2015) Yuanyuan Jiang et al.   Scientific Reports

Gastrointestinal Microbiota–Mediated Control of Enteric Pathogens

(2014) Sophie Yurist-Doutsch et al.   Annual Review of Genetics

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Genetically encoded reporters for hyperpolarized xenon magnetic resonance imaging

(2014) Mikhail G. Shapiro et al.   Nature Chemistry

Biogenic gas nanostructures as ultrasonic molecular reporters

(2014) Mikhail G. Shapiro et al.   Nature Nanotechnology

A brief history of synthetic biology

(2014) D. Ewen Cameron et al.   NATURE REVIEWS MICROBIOLOGY

Synthetic biology in mammalian cells: next generation research tools and therapeutics

(2014) Florian Lienert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Microbes As Drug Delivery Systems

(2014) Jan Claesen et al.   ACS Synthetic Biology

Human Protamine-1 as an MRI Reporter Gene Based on Chemical Exchange

(2013) Amnon Bar-Shir et al.   ACS Chemical Biology

The role of microbiome in central nervous system disorders

(2013) Yan Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Transforming Thymidine into a Magnetic Resonance Imaging Probe for Monitoring Gene Expression

(2013) Amnon Bar-Shir et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic circuits integrating logic and memory in living cells

(2013) Piro Siuti et al.   NATURE BIOTECHNOLOGY

Synthesis of a probe for monitoring HSV1-tk reporter gene expression using chemical exchange saturation transfer MRI

(2013) Amnon Bar-Shir et al.   Nature Protocols

Visualizing cellular interactions with a generalized proximity reporter

(2013) M. A. Sellmyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-1- and CTLA-4-Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses

(2013) V. D. Fedorov et al.   Science Translational Medicine

Cell-Based Therapeutics: The Next Pillar of Medicine

(2013) M. A. Fischbach et al.   Science Translational Medicine

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010

(2012) Rebecca Smith-Bindman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MRI biosensor for protein kinase A encoded by a single synthetic gene

(2012) Raag D. Airan et al.   MAGNETIC RESONANCE IN MEDICINE

Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs

(2012) L. V. Wang et al.   SCIENCE

Engineered E. coli That Detect and Respond to Gut Inflammation through Nitric Oxide Sensing

(2012) Eric J. Archer et al.   ACS Synthetic Biology

Monitoring Enzyme Activity Using a Diamagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agent

(2011) Guanshu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Noninvasive cell-tracking methods

(2011) Moritz F. Kircher et al.   Nature Reviews Clinical Oncology

Synthetic Biology Moving into the Clinic

(2011) W. C. Ruder et al.   SCIENCE

A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice

(2011) H. Ye et al.   SCIENCE

Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine

(2010) Mikhail G Shapiro et al.   NATURE BIOTECHNOLOGY

Self-sufficient control of urate homeostasis in mice by a synthetic circuit

(2010) Christian Kemmer et al.   NATURE BIOTECHNOLOGY

Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit

(2010) Qiang Ni et al.   Nature Chemical Biology

Remote control of ion channels and neurons through magnetic-field heating of nanoparticles

(2010) Heng Huang et al.   Nature Nanotechnology

Guided by the light: visualizing biomolecular processes in living animals with bioluminescence

(2009) Jennifer A Prescher et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Image-guided, noninvasive, spatiotemporal control of gene expression

(2009) R. Deckers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria

(2008) Jerry M. Wells et al.   NATURE REVIEWS MICROBIOLOGY

Noninvasive detection of therapeutic cytolytic T cells with 18F–FHBG PET in a patient with glioma

(2008) Shahriar S Yaghoubi et al.   Nature clinical practice. Oncology