Tunable thermal bioswitches for in vivo control of microbial therapeutics

Synthetic biology expands chemical control of microorganisms

(2015) Tyler J Ford et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Designing Cell-Type-Specific Genome-wide Experiments

(2015) Ava Handley et al.   MOLECULAR CELL

'Deadman' and 'Passcode' microbial kill switches for bacterial containment

(2015) Clement T Y Chan et al.   Nature Chemical Biology

De novodesign of heat-repressible RNA thermosensors inE. coli

(2015) Allison Hoynes-O'Connor et al.   NUCLEIC ACIDS RESEARCH

Multilayered genetic safeguards limit growth of microorganisms to defined environments

(2015) Ryan R. Gallagher et al.   NUCLEIC ACIDS RESEARCH

Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates

(2015) Alexis Courbet et al.   Science Translational Medicine

Programmable probiotics for detection of cancer in urine

(2015) Tal Danino et al.   Science Translational Medicine

Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota

(2015) Mark Mimee et al.   Cell Systems

Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

(2014) Kathrin Lang et al.   CHEMICAL REVIEWS

Programmable bacteria detect and record an environmental signal in the mammalian gut

(2014) Jonathan W. Kotula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lipid-mediated conformational switch modulates the thermosensing activity of DesK

(2014) María Eugenia Inda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Microbes As Drug Delivery Systems

(2014) Jan Claesen et al.   ACS Synthetic Biology

Chemical reporters for biological discovery

(2013) Markus Grammel et al.   Nature Chemical Biology

A Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor

(2013) W. Jeffrey Elias et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell-Based Therapeutics: The Next Pillar of Medicine

(2013) M. A. Fischbach et al.   Science Translational Medicine

Substrate Profile and Metal-ion Selectivity of Human Divalent Metal-ion Transporter-1

(2012) Anthony C. Illing et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild Hyperthermia

(2012) Brett Z. Fite et al.   PLoS One

Engineered E. coli That Detect and Respond to Gut Inflammation through Nitric Oxide Sensing

(2012) Eric J. Archer et al.   ACS Synthetic Biology

LacI(Ts)-Regulated Expression as an In Situ Intracellular Biomolecular Thermometer

(2011) K. M. McCabe et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Clinical and future applications of high intensity focused ultrasound in cancer

(2011) Osama Al-Bataineh et al.   CANCER TREATMENT REVIEWS

Recombinant lactic acid bacteria as mucosal biotherapeutic agents

(2011) Catherine Daniel et al.   TRENDS IN BIOTECHNOLOGY

Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters

(2010) Norma A Valdez-Cruz et al.   Microbial Cell Factories

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Translation on demand by a simple RNA-based thermosensor

(2010) Jens Kortmann et al.   NUCLEIC ACIDS RESEARCH

A modular positive feedback-based gene amplifier

(2010) Goutam J Nistala et al.   Journal of Biological Engineering

Image-guided, noninvasive, spatiotemporal control of gene expression

(2009) R. Deckers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of synthetic RNA-based thermosensors

(2008) Torsten Waldminghaus et al.   BIOLOGICAL CHEMISTRY

Hue-shifted monomeric variants of Clavularia cyan fluorescent protein: identification of the molecular determinants of color and applications in fluorescence imaging

(2008) Hui-wang Ai et al.   BMC BIOLOGY

Clinical applications of magnetic nanoparticles for hyperthermia

(2008) Burghard Thiesen et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria

(2008) Jerry M. Wells et al.   NATURE REVIEWS MICROBIOLOGY

Design of simple synthetic RNA thermometers for temperature-controlled gene expression in Escherichia coli

(2008) J. Neupert et al.   NUCLEIC ACIDS RESEARCH