Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond
Authors
Keywords
-
Journal
MOLECULAR CARCINOGENESIS
Volume 56, Issue 12, Pages 2543-2557
Publisher
Wiley
Online
2017-06-02
DOI
10.1002/mc.22690
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The primary cilium as a cellular receiver: organizing ciliary GPCR signaling
- (2016) Keren I Hilgendorf et al. CURRENT OPINION IN CELL BIOLOGY
- Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium
- (2016) Kasturi Pal et al. JOURNAL OF CELL BIOLOGY
- Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis
- (2016) Ying Liu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell carcinoma
- (2016) Reinhard Dummer et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells
- (2016) Z Xu et al. LEUKEMIA
- Defining the clonal dynamics leading to mouse skin tumour initiation
- (2016) Adriana Sánchez-Danés et al. NATURE
- Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
- (2016) Ximena Bonilla et al. NATURE GENETICS
- Long-noncoding RNAs in basal cell carcinoma
- (2016) Michael Sand et al. TUMOR BIOLOGY
- An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
- (2016) Karsten Boldt et al. Nature Communications
- DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance
- (2016) Wolfgang Gruber et al. Oncotarget
- PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail
- (2016) Kai Jiang et al. PLOS BIOLOGY
- Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease
- (2016) Wesley R. Lewis et al. PLoS Genetics
- Hedgehog Blockade for Basal Cell Carcinoma
- (2016) Albert Rübben et al. JAMA Dermatology
- Increased Risk of Cutaneous Squamous Cell Carcinoma After Vismodegib Therapy for Basal Cell Carcinoma
- (2016) Shalini V. Mohan et al. JAMA Dermatology
- Multiple Hereditary Infundibulocystic Basal Cell Carcinoma Syndrome Associated With a GermlineSUFUMutation
- (2016) Joshua M. Schulman et al. JAMA Dermatology
- Hedgehog Pathway Inhibitor Therapy for Locally Advanced and Metastatic Basal Cell Carcinoma
- (2016) Audrey A. Jacobsen et al. JAMA Dermatology
- Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation
- (2016) Bomi Jung et al. PLoS One
- Prevalence and Costs of Skin Cancer Treatment in the U.S., 2002−2006 and 2007−2011
- (2015) Gery P. Guy et al. AMERICAN JOURNAL OF PREVENTIVE MEDICINE
- Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismodegib therapy: an integrative molecular and surgical case study
- (2015) M. Sand et al. ANNALS OF ONCOLOGY
- Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways
- (2015) Shixuan Wang et al. Autophagy
- Vismodegib Resistance in Basal Cell Carcinoma: Not a Smooth Fit
- (2015) Todd W. Ridky et al. CANCER CELL
- Smoothened Variants Explain the Majority of Drug Resistance in Basal Cell Carcinoma
- (2015) Scott X. Atwood et al. CANCER CELL
- Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma
- (2015) Hayley J. Sharpe et al. CANCER CELL
- RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors
- (2015) X. Zhao et al. CANCER RESEARCH
- Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis
- (2015) N. Yang et al. DEVELOPMENT
- Notch Activity Modulates the Responsiveness of Neural Progenitors to Sonic Hedgehog Signaling
- (2015) Jennifer H. Kong et al. DEVELOPMENTAL CELL
- Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output
- (2015) Marcelo Chávez et al. DEVELOPMENTAL CELL
- Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
- (2015) Francesc R. Garcia-Gonzalo et al. DEVELOPMENTAL CELL
- Efficacy of Hedgehog Pathway Inhibitors in Basal Cell Carcinoma
- (2015) N. Basset-Seguin et al. MOLECULAR CANCER THERAPEUTICS
- Current concept of photocarcinogenesis
- (2015) Chikako Nishisgori PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- New basal cell carcinoma susceptibility loci
- (2015) Simon N. Stacey et al. Nature Communications
- Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome
- (2014) M. Athar et al. CANCER RESEARCH
- Phase I Dose-Escalation Trial of the Oral Investigational Hedgehog Signaling Pathway Inhibitor TAK-441 in Patients with Advanced Solid Tumors
- (2014) J. Goldman et al. CLINICAL CANCER RESEARCH
- Multiciliated Cells
- (2014) Eric R. Brooks et al. CURRENT BIOLOGY
- EFCAB7 and IQCE Regulate Hedgehog Signaling by Tethering the EVC-EVC2 Complex to the Base of Primary Cilia
- (2014) Ganesh V. Pusapati et al. DEVELOPMENTAL CELL
- Open-Label, Exploratory Phase II Trial of Oral Itraconazole for the Treatment of Basal Cell Carcinoma
- (2014) Daniel J. Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Role of CRD-BP in the Growth of Human Basal Cell Carcinoma Cells
- (2014) Felicite K. Noubissi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Smoothened (SMO) receptor mutations dictate resistance to vismodegib in basal cell carcinoma
- (2014) Sabrina Pricl et al. Molecular Oncology
- From the cytoplasm into the cilium: Bon voyage
- (2014) Jarema Malicki et al. Organogenesis
- Cilia-Mediated Hedgehog Signaling in Drosophila
- (2014) Anujaianthi Kuzhandaivel et al. Cell Reports
- Role of the miR-17 92 cluster family in cerebellar and medulloblastoma development
- (2014) F. Zindy et al. Biology Open
- PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition
- (2013) C. Metcalfe et al. CANCER RESEARCH
- Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential
- (2013) B De Craene et al. CELL DEATH AND DIFFERENTIATION
- U.S. Food and Drug Administration Approval: Vismodegib for Recurrent, Locally Advanced, or Metastatic Basal Cell Carcinoma
- (2013) M. Axelson et al. CLINICAL CANCER RESEARCH
- Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
- (2013) A. Jimeno et al. CLINICAL CANCER RESEARCH
- Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
- (2012) Anette Weyergang et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Cilia functions in development
- (2012) Iain A Drummond CURRENT OPINION IN CELL BIOLOGY
- A Smoothened-Evc2 Complex Transduces the Hedgehog Signal at Primary Cilia
- (2012) Karolin V. Dorn et al. DEVELOPMENTAL CELL
- The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ
- (2012) Sandra Habbig et al. HUMAN MOLECULAR GENETICS
- Hedgehog pathway inhibition and the race against tumor evolution
- (2012) Scott X. Atwood et al. JOURNAL OF CELL BIOLOGY
- Myc proteins in brain tumor development and maintenance
- (2012) Fredrik J. Swartling UPSALA JOURNAL OF MEDICAL SCIENCES
- Correlation of Global MicroRNA Expression With Basal Cell Carcinoma Subtype
- (2012) Christopher Heffelfinger et al. G3-Genes Genomes Genetics
- MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma
- (2012) E Sonkoly et al. Oncogenesis
- Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer
- (2011) Y. A. Yoo et al. CANCER RESEARCH
- A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development
- (2011) Ellen J. Ezratty et al. CELL
- MicroRNA-based silencing of Delta/Notch signaling promotes multiple cilia formation
- (2011) Brice Marcet et al. CELL CYCLE
- Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors
- (2011) P. M. LoRusso et al. CLINICAL CANCER RESEARCH
- Role of epidermal primary cilia in the homeostasis of skin and hair follicles
- (2011) M. J. Croyle et al. DEVELOPMENT
- Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
- (2011) M. Tuson et al. DEVELOPMENT
- Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia
- (2011) J. B. Wallingford et al. GENES & DEVELOPMENT
- NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway
- (2011) Sandra Habbig et al. JOURNAL OF CELL BIOLOGY
- Topical Treatment of Basal Cell Carcinomas in Nevoid Basal Cell Carcinoma Syndrome with a Smoothened Inhibitor
- (2011) Hans Skvara et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Non-melanoma skin cancer
- (2010) Vishal Madan et al. LANCET
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway
- (2009) Harald Schnidar et al. CANCER RESEARCH
- Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway
- (2009) Alla Maloverjan et al. EXPERIMENTAL CELL RESEARCH
- Cloning of the HumanGLI2Promoter
- (2009) Sylviane Dennler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella
- (2009) Thomas Heuser et al. JOURNAL OF CELL BIOLOGY
- Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/ -Catenin Signaling Pathway
- (2009) O. Saydam et al. MOLECULAR AND CELLULAR BIOLOGY
- Application of Active and Kinase-Deficient Kinome Collection for Identification of Kinases Regulating Hedgehog Signaling
- (2008) Markku Varjosalo et al. CELL
- An Essential Role for Dermal Primary Cilia in Hair Follicle Morphogenesis
- (2008) Jonathan M. Lehman et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Dose- and Route-Dependent Teratogenicity, Toxicity, and Pharmacokinetic Profiles of the Hedgehog Signaling Antagonist Cyclopamine in the Mouse
- (2008) Robert J. Lipinski et al. TOXICOLOGICAL SCIENCES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now