PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

Title
PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models
Authors
Keywords
Predictive biomarkers, PARP1 inhibitors, DNA-damaging agents, Trabectedin, Olaparib, Bone and soft tissue sarcomas, Drug synergism
Journal
Molecular Cancer
Volume 16, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-04-28
DOI
10.1186/s12943-017-0652-5

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