Specialized Plant Metabolism Characteristics and Impact on Target Molecule Biotechnological Production

Jasmonates are signals in the biosynthesis of secondary metabolites — Pathways, transcription factors and applied aspects — A brief review

(2017) Claus Wasternack et al.   New Biotechnology

Adventitious root culture of Polygonum multiflorum for phenolic compounds and its pilot-scale production in 500 L-tank

(2017) Thanh-Tam Ho et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Optimizing culture conditions for establishment of hairy root culture of Semecarpus anacardium L.

(2017) Bhuban Mohan Panda et al.   3 Biotech

Optimizing culture conditions for establishment of hairy root culture of Semecarpus anacardium L.

(2017) Bhuban Mohan Panda et al.   3 Biotech

Transporter and its engineering for secondary metabolites

(2016) Huajun Lv et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Plant cell culture strategies for the production of natural products

(2016) Marisol Ochoa-Villarreal et al.   BMB Reports

The bioactive monoterpene indole alkaloid N,β-d-glucopyranosyl vincosamide is regulated by irradiance quality and development in Psychotria leiocarpa

(2016) Hélio Nitta Matsuura et al.   INDUSTRIAL CROPS AND PRODUCTS

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Elicitation, an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories

(2016) Karla Ramirez-Estrada et al.   MOLECULES

Revolutionizing plant biology: multiple ways of genome engineering by CRISPR/Cas

(2016) Simon Schiml et al.   Plant Methods

Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum

(2016) Tomas Laursen et al.   SCIENCE

Effect of Different Agrobacterium rhizogenes Strains on Hairy Root Induction and Phenylpropanoid Biosynthesis in Tartary Buckwheat (Fagopyrum tataricum Gaertn)

(2016) Aye Thwe et al.   Frontiers in Microbiology

Global Plant Stress Signaling: Reactive Oxygen Species at the Cross-Road

(2016) Nasser Sewelam et al.   Frontiers in Plant Science

Engineering of Secondary Metabolism

(2015) Sarah E. O'Connor   Annual Review of Genetics

Model based fed batch cultivation and elicitation for the overproduction of ajmalicine from hairy roots of Catharanthus roseus

(2015) Dhara Thakore et al.   BIOCHEMICAL ENGINEERING JOURNAL

Biosynthesis and biotechnological production of ginsenosides

(2015) Yu-Jin Kim et al.   BIOTECHNOLOGY ADVANCES

Convergent Strategies in Total Syntheses of Complex Terpenoids

(2015) Daisuke Urabe et al.   CHEMICAL REVIEWS

High-value products from plants: the challenges of process optimization

(2015) Rainer Fischer et al.   CURRENT OPINION IN BIOTECHNOLOGY

Establishment of transgenic Rhazya stricta hairy roots to modulate terpenoid indole alkaloid production

(2015) Amir Akhgari et al.   PLANT CELL REPORTS

Artemisinin production by plant hairy root cultures in gas- and liquid-phase bioreactors

(2015) Nivedita Patra et al.   PLANT CELL REPORTS

Hairy root biotechnology—indicative timeline to understand missing links and future outlook

(2015) Shakti Mehrotra et al.   PROTOPLASMA

Complete biosynthesis of opioids in yeast

(2015) S. Galanie et al.   SCIENCE

Paclitaxel Through the Ages of Anticancer Therapy: Exploring Its Role in Chemoresistance and Radiation Therapy

(2015) Anna Barbuti et al.   Cancers

Improvement of hairy root cultures and plants by changing biosynthetic pathways leading to pharmaceutical metabolites: Strategies and applications

(2014) Jutta Ludwig-Müller et al.   BIOTECHNOLOGY ADVANCES

Enhancement of ginsenoside biosynthesis and secretion by Tween 80 inPanax ginsenghairy roots

(2014) Yanlong Liang et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Modeling of plant in vitro cultures: Overview and estimation of biotechnological processes

(2014) Rüdiger W. Maschke et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biotechnological approaches to the production of shikonins: a critical review with recent updates

(2014) Sonia Malik et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Medicinal plant cell suspension cultures: pharmaceutical applications and high-yielding strategies for the desired secondary metabolites

(2014) Wei Yue et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

A look inside an alkaloid multisite plant: the Catharanthus logistics

(2014) Vincent Courdavault et al.   CURRENT OPINION IN PLANT BIOLOGY

Making iridoids/secoiridoids and monoterpenoid indole alkaloids: progress on pathway elucidation

(2014) Vincenzo De Luca et al.   CURRENT OPINION IN PLANT BIOLOGY

Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation

(2014) Hosakatte Niranjana Murthy et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Changing trends in biotechnology of secondary metabolism in medicinal and aromatic plants

(2014) Sumit G. Gandhi et al.   PLANTA

The rise of operon-like gene clusters in plants

(2014) Svetlana Boycheva et al.   TRENDS IN PLANT SCIENCE

Threats and opportunities of plant pathogenic bacteria

(2013) Petr Tarkowski et al.   BIOTECHNOLOGY ADVANCES

Oxidative stress and production of bioactive monoterpene indole alkaloids: biotechnological implications

(2013) Hélio Nitta Matsuura et al.   BIOTECHNOLOGY LETTERS

Gene clustering in plant specialized metabolism

(2013) Hans-Wilhelm Nützmann et al.   CURRENT OPINION IN BIOTECHNOLOGY

Improved production of bioactive valepotriates in whole-plant liquid cultures of Valeriana glechomifolia

(2013) Denise Russowski et al.   INDUSTRIAL CROPS AND PRODUCTS

Root-zone temperature alters alkaloid synthesis and accumulation in Catharanthus roseus and Nicotiana tabacum

(2013) Sonia Malik et al.   INDUSTRIAL CROPS AND PRODUCTS

Plant Flavonoids—Biosynthesis, Transport and Involvement in Stress Responses

(2013) Elisa Petrussa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biologyin vivoandin vitro

(2013) Tessa Moses et al.   NEW PHYTOLOGIST

Accumulation of brachycerine, an antioxidant glucosidic indole alkaloid, is induced by abscisic acid, heavy metal, and osmotic stress in leaves of Psychotria brachyceras

(2013) Naíla Cannes do Nascimento et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Accumulation of a bioactive triterpene saponin fraction of Quillaja brasiliensis leaves is associated with abiotic and biotic stresses

(2013) Fernanda de Costa et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Efficient metabolic pathway engineering in transgenic tobacco and tomato plastids with synthetic multigene operons

(2013) Y. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus

(2013) F. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering Microbial Cells for the Biosynthesis of Natural Compounds of Pharmaceutical Significance

(2013) Philippe Jeandet et al.   Biomed Research International

Living between two worlds: two-phase culture systems for producing plant secondary metabolites

(2012) Sonia Malik et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

The challenges of cellular compartmentalization in plant metabolic engineering

(2012) Uwe Heinig et al.   CURRENT OPINION IN BIOTECHNOLOGY

The emerging field of transport engineering of plant specialized metabolites

(2012) Hussam Hassan Nour-Eldin et al.   CURRENT OPINION IN BIOTECHNOLOGY

The major indole alkaloid N,β-D-glucopyranosyl vincosamide from leaves ofPsychotria leiocarpaCham. & Schltdl. is not an antifeedant but shows broad antioxidant activity

(2012) Hélio Nitta Matsuura et al.   NATURAL PRODUCT RESEARCH

Engineering of benzylglucosinolate in tobacco provides proof-of-concept for dead-end trap crops genetically modified to attract Plutella xylostella (diamondback moth)

(2012) Morten E. Møldrup et al.   PLANT BIOTECHNOLOGY JOURNAL

Cellular aggregation is a key parameter associated with long term variability in paclitaxel accumulation in Taxus suspension cultures

(2012) Rohan A. Patil et al.   PLANT CELL TISSUE AND ORGAN CULTURE

The effect of light on gene expression and podophyllotoxin biosynthesis in Linum album cell culture

(2012) Morteza Yousefzadi et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Overexpression of ORCA3 and G10H in Catharanthus roseus Plants Regulated Alkaloid Biosynthesis and Metabolism Revealed by NMR-Metabolomics

(2012) Qifang Pan et al.   PLoS One

Genetically transformed roots: from plant disease to biotechnological resource

(2012) Milen I. Georgiev et al.   TRENDS IN BIOTECHNOLOGY

Transcriptional machineries in jasmonate-elicited plant secondary metabolism

(2012) Nathan De Geyter et al.   TRENDS IN PLANT SCIENCE

Multi-dimensional regulation of metabolic networks shaping plant development and performance

(2011) R. Kooke et al.   JOURNAL OF EXPERIMENTAL BOTANY

Engineering secondary metabolite production in hairy roots

(2011) Sheela Chandra et al.   PHYTOCHEMISTRY REVIEWS

Combining Genome-Wide Association Mapping and Transcriptional Networks to Identify Novel Genes Controlling Glucosinolates in Arabidopsis thaliana

(2011) Eva K. F. Chan et al.   PLOS BIOLOGY

Salicylic acid improves podophyllotoxin production in cell cultures of Linum album by increasing the expression of genes related with its biosynthesis

(2010) Morteza Yousefzadi et al.   BIOTECHNOLOGY LETTERS

Physico-chemical factors influencing the shikonin derivatives production in cell suspension cultures ofArnebia euchroma(Royle) Johnston, a medicinally important plant species

(2010) Sonia Malik et al.   CELL BIOLOGY INTERNATIONAL

Podophyllotoxin: Current approaches to its biotechnological production and future challenges

(2010) Morteza Yousefzadi et al.   ENGINEERING IN LIFE SCIENCES

Plant volatile terpenoid metabolism: Biosynthetic genes, transcriptional regulation and subcellular compartmentation

(2010) Dinesh A. Nagegowda   FEBS LETTERS

Qualitative and quantitative analysis of anthraquinone derivatives in rhizomes of tissue culture-raised Rheum emodi Wall. plants

(2010) Sonia Malik et al.   JOURNAL OF PLANT PHYSIOLOGY

The expression of 1-deoxy-d-xylulose synthase and geraniol-10-hydroxylase or anthranilate synthase increases terpenoid indole alkaloid accumulation in Catharanthus roseus hairy roots

(2010) Christie A.M. Peebles et al.   METABOLIC ENGINEERING

Optimization of podophyllotoxin extraction method fromLinum albumcell cultures

(2010) Morteza Yousefzadi et al.   PHARMACEUTICAL BIOLOGY

The multiplicity of hairy root cultures: Prolific possibilities

(2010) Nadia N. Ono et al.   PLANT SCIENCE

A remorin protein interacts with symbiotic receptors and regulates bacterial infection

(2010) B. Lefebvre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scopolamine, anisodamine and hyoscyamine production by Brugmansia candida hairy root cultures in bioreactors

(2010) Alejandra Beatriz Cardillo et al.   PROCESS BIOCHEMISTRY

Secondary metabolic gene clusters: evolutionary toolkits for chemical innovation

(2010) Anne Osbourn   TRENDS IN GENETICS

Morphology and withanolide production ofWithania coagulanshairy root cultures

(2009) Hossein M. Mirjalili et al.   ENGINEERING IN LIFE SCIENCES

Transformed Hairy Roots ofArachis hypogea: A Tool for Studying Root Nodule Symbiosis in a Non–Infection Thread Legume of the Aeschynomeneae Tribe

(2009) Senjuti Sinharoy et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Alkaloid Biosynthesis: Metabolism and Trafficking

(2008) Jörg Ziegler et al.   Annual Review of Plant Biology

Functions of rol genes in plant secondary metabolism

(2008) Victor P. Bulgakov   BIOTECHNOLOGY ADVANCES

PlantPAN: Plant promoter analysis navigator, for identifying combinatorial cis-regulatory elements with distance constraint in plant gene groups

(2008) Wen-Chi Chang et al.   BMC GENOMICS

Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors

(2008) Eugenio Butelli et al.   NATURE BIOTECHNOLOGY

Coordination of gene expression between organellar and nuclear genomes

(2008) Jesse D. Woodson et al.   NATURE REVIEWS GENETICS

Morphometric and biochemical characterization of red beet (Beta vulgaris L.) hairy roots obtained after single and double transformations

(2008) R. Thimmaraju et al.   PLANT CELL REPORTS

Reconfiguration of the Achene and Receptacle Metabolic Networks during Strawberry Fruit Development

(2008) A. Fait et al.   PLANT PHYSIOLOGY

Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development

(2008) Michael F Covington et al.   GENOME BIOLOGY