Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes

The Combined Landscape of Denisovan and Neanderthal Ancestry in Present-Day Humans

(2016) Sriram Sankararaman et al.   CURRENT BIOLOGY

Detection of human adaptation during the past 2000 years

(2016) Yair Field et al.   SCIENCE

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Circulating Very-Long-Chain Saturated Fatty Acids and Incident Coronary Heart Disease in US Men and WomenCLINICAL PERSPECTIVE

(2015) Vasanti S. Malik et al.   CIRCULATION

Genome-wide patterns of selection in 230 ancient Eurasians

(2015) Iain Mathieson et al.   NATURE

Population genomics of Bronze Age Eurasia

(2015) Morten E. Allentoft et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Greenlandic Inuit show genetic signatures of diet and climate adaptation

(2015) M. Fumagalli et al.   SCIENCE

Human Evolution: Genomic Gifts from Archaic Hominins

(2014) Benjamin Vernot et al.   CURRENT BIOLOGY

Identifying Causal Variants at Loci with Multiple Signals of Association

(2014) F. Hormozdiari et al.   GENETICS

Fattyaciddesaturase 1gene polymorphisms control human hepatic lipid composition

(2014) Libo Wang et al.   HEPATOLOGY

Relationship between a Common Variant in the Fatty Acid Desaturase (FADS) Cluster and Eicosanoid Generation in Humans

(2014) Austin G. Hester et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genomic landscape of Neanderthal ancestry in present-day humans

(2014) Sriram Sankararaman et al.   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

A Model-Based Approach for Identifying Signatures of Ancient Balancing Selection in Genetic Data

(2014) Michael DeGiorgio et al.   PLoS Genetics

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Genetic Adaptation of Fatty-Acid Metabolism: A Human-Specific Haplotype Increasing the Biosynthesis of Long-Chain Omega-3 and Omega-6 Fatty Acids

(2012) Adam Ameur et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Protocol for ADDITION-PRO: a longitudinal cohort study of the cardiovascular experience of individuals at high risk for diabetes recruited from Danish primary care

(2012) Nanna B Johansen et al.   BMC PUBLIC HEALTH

Association Between Omega-3 Fatty Acid Supplementation and Risk of Major Cardiovascular Disease Events

(2012) Evangelos C. Rizos et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Unsupervised pattern discovery in human chromatin structure through genomic segmentation

(2012) Michael M Hoffman et al.   NATURE METHODS

Adaptive Evolution of the FADS Gene Cluster within Africa

(2012) Rasika A. Mathias et al.   PLoS One

Insertion–deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin

(2012) Holly T. Reardon et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

A High-Coverage Genome Sequence from an Archaic Denisovan Individual

(2012) M. Meyer et al.   SCIENCE

Protein Interaction-Based Genome-Wide Analysis of Incident Coronary Heart Disease

(2011) Majken K. Jensen et al.   Circulation-Cardiovascular Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

pegas: an R package for population genetics with an integrated-modular approach

(2010) E. Paradis   BIOINFORMATICS

Single nucleotide polymorphisms in theFADSgene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios

(2010) Szilvia Bokor et al.   JOURNAL OF LIPID RESEARCH

Omega-3 polyunsaturated acids and cardiovascular disease: notable ethnic differences or unfulfilled promise?

(2010) J. V. PATEL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

Enredo and Pecan: Genome-wide mammalian consistency-based multiple alignment with paralogs

(2008) B. Paten et al.   GENOME RESEARCH