TNF-α potentiates uric acid-induced interleukin-1β (IL-1β) secretion in human neutrophils

Canakinumab for the treatment of TNF-receptor associated periodic syndrome

(2017) F La Torre et al.   Expert Review of Clinical Immunology

Inflammasome Priming in Sterile Inflammatory Disease

(2017) Meghana N. Patel et al.   TRENDS IN MOLECULAR MEDICINE

Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome

(2016) Rebecca Torene et al.   ANNALS OF THE RHEUMATIC DISEASES

Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study

(2016) Marco Gattorno et al.   ANNALS OF THE RHEUMATIC DISEASES

Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances

(2016) Franz Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Interleukin-1 as a therapeutic target in gout

(2015) Alexandre Dumusc et al.   CURRENT OPINION IN RHEUMATOLOGY

Transmembrane TNF-α is sufficient for articular inflammation and hypernociception in a mouse model of gout

(2015) Flávio A. Amaral et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1

(2015) Obada R. Shamaa et al.   PLoS One

IL-1 Blockade in Autoinflammatory Syndromes

(2014) Adriana A. Jesus et al.   Annual Review of Medicine

Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts

(2014) Claudia Casnici et al.   MEDIATORS OF INFLAMMATION

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

(2013) Rebeccah J Mathews et al.   ANNALS OF THE RHEUMATIC DISEASES

Advances in the treatment of inflammatory arthritis

(2012) David S. Pisetsky et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Uric acid as a danger signal in gout and its comorbidities

(2012) Kenneth L. Rock et al.   Nature Reviews Rheumatology

Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts

(2012) Kiyoshi Migita et al.   ARTHRITIS RESEARCH & THERAPY

Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout

(2011) William John Martin et al.   ARTHRITIS AND RHEUMATISM

Two signal models in innate immunity

(2011) Mary F. Fontana et al.   IMMUNOLOGICAL REVIEWS

Molecular mechanisms of inflammasome activation during microbial infections

(2011) Petr Broz et al.   IMMUNOLOGICAL REVIEWS

The essential roles of Toll-like receptor signaling pathways in sterile inflammatory diseases

(2011) Qing Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Autoinflammatory Disease Reloaded: A Clinical Perspective

(2010) Daniel L. Kastner et al.   CELL

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Cutting Edge: TNF-  Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

(2009) L. Franchi et al.   JOURNAL OF IMMUNOLOGY