Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups

Morphological and Immunohistochemical Reevaluation of Tumors Initially Diagnosed as Ovarian Endometrioid Carcinoma With Emphasis on High-grade Tumors

(2016) Diana Lim et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas

(2016) Adele Wong et al.   GYNECOLOGIC ONCOLOGY

Significant frequency of MSH2/MSH6 abnormality in ovarian endometrioid carcinoma supports histotype-specific Lynch syndrome screening in ovarian carcinomas

(2016) Peter F Rambau et al.   HISTOPATHOLOGY

The Genomic Heterogeneity of FIGO Grade 3 Endometrioid Carcinoma Impacts Diagnostic Accuracy and Reproducibility

(2016) Yaser R. Hussein et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy

(2016) Sung-Min Ahn et al.   Oncotarget

A clinically applicable molecular-based classification for endometrial cancers

(2015) A Talhouk et al.   BRITISH JOURNAL OF CANCER

POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

(2015) I. C. van Gool et al.   CLINICAL CANCER RESEARCH

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers

(2015) Anne ML Jansen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

POLE mutations in families predisposed to cutaneous melanoma

(2015) Lauren G. Aoude et al.   Familial Cancer

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Histopathological features of endometrial carcinomas associated withPOLEmutations: implications for decisions about adjuvant therapy

(2015) Salwa Bakhsh et al.   HISTOPATHOLOGY

Frequency and phenotypic spectrum of germline mutations inPOLEand seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas

(2015) Isabel Spier et al.   INTERNATIONAL JOURNAL OF CANCER

Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma

(2015) Lien N. Hoang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations

(2015) Jordan Lerner-Ellis et al.   JOURNAL OF MEDICAL GENETICS

SomaticPOLEmutations cause an ultramutated giant cell high-grade glioma subtype with better prognosis

(2015) E. Zeynep Erson-Omay et al.   NEURO-ONCOLOGY

Polymerase ɛ (POLE) mutations in endometrial cancer: Clinical outcomes and implications for Lynch syndrome testing

(2014) Caroline C. Billingsley et al.   CANCER

A Common Cancer-Associated DNA Polymerase   Mutation Causes an Exceptionally Strong Mutator Phenotype, Indicating Fidelity Defects Distinct from Loss of Proofreading

(2014) D. P. Kane et al.   CANCER RESEARCH

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

(2014) D. Mouradov et al.   CANCER RESEARCH

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

(2014) Eve Shinbrot et al.   GENOME RESEARCH

POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium

(2014) Bo Meng et al.   GYNECOLOGIC ONCOLOGY

Lynch Syndrome in patients with clear cell and endometrioid cancers of the ovary

(2014) Koah R. Vierkoetter et al.   GYNECOLOGIC ONCOLOGY

Ovarian and endometrial endometrioid adenocarcinomas have distinct profiles of microsatellite instability, PTEN expression, and ARID1A expression

(2014) Hsien-Neng Huang et al.   HISTOPATHOLOGY

Prognostic Significance of POLE Proofreading Mutations in Endometrial Cancer

(2014) David N. Church et al.   JNCI-Journal of the National Cancer Institute

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

(2014) Siân Jones et al.   Nature Communications

Mutations in POLE and survival of colorectal cancer patients - link to disease stage and treatment

(2014) Albrecht Stenzinger et al.   Cancer Medicine

Histotype-Genotype Correlation in 36 High-grade Endometrial Carcinomas

(2013) Lien N. Hoang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Poor Interobserver Reproducibility in the Diagnosis of High-grade Endometrial Carcinoma

(2013) C. Blake Gilks et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

(2013) O. D. Abaan et al.   CANCER RESEARCH

Ovarian carcinoma histotype determination is highly reproducible, and is improved through the use of immunohistochemistry

(2013) Martin Köbel et al.   HISTOPATHOLOGY

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

(2013) David N. Church et al.   HUMAN MOLECULAR GENETICS

Reproducibility of histological cell type in high-grade endometrial carcinoma

(2013) Guangming Han et al.   MODERN PATHOLOGY

Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles

(2013) Melissa K McConechy et al.   MODERN PATHOLOGY

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Ovarian Endometrioid Adenocarcinoma

(2011) Anil Aysal et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Diagnosis of Ovarian Carcinoma Cell Type is Highly Reproducible

(2010) Martin Köbel et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Differences in Tumor Type in Low-stage Versus High-stage Ovarian Carcinomas

(2010) Martin Köbel et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Calculator for ovarian carcinoma subtype prediction

(2010) Steve E Kalloger et al.   MODERN PATHOLOGY

ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

(2010) Kimberly C. Wiegand et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathogenetic Pathways in Ovarian Endometrioid Adenocarcinoma

(2009) Julia Turbiner Geyer et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma

(2008) C. Blake Gilks et al.   HUMAN PATHOLOGY

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

(2008) Martin Köbel et al.   PLOS MEDICINE