The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy

Published 2016 View Full Article

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Title
The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy
Authors
Keywords
early-onset colorectal cancer, POLE, hypermutation, immunotherapy, PD-1 blockade
Journal
Oncotarget
Volume 7, Issue 42, Pages -
Publisher
Impact Journals, LLC
Online
2016-09-07
DOI
10.18632/oncotarget.11862

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