SMARCA4-deficient thoracic sarcoma: a distinctive clinicopathological entity with undifferentiated rhabdoid morphology and aggressive behavior

Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities

(2017) Akihiko Yoshida et al.   MODERN PATHOLOGY

Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas

(2017) Inga-Marie Schaefer et al.   MODERN PATHOLOGY

Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models

(2017) Elayne Chan-Penebre et al.   MOLECULAR CANCER THERAPEUTICS

Loss of SMARCA4 Expression Is Both Sensitive and Specific for the Diagnosis of Small Cell Carcinoma of Ovary, Hypercalcemic Type

(2016) Niamh Conlon et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SWI/SNF Complex–deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract

(2016) Abbas Agaimy et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics

(2016) Blaise A Clarke et al.   HISTOPATHOLOGY

Immunophenotypic features of dedifferentiated endometrial carcinoma - insights from BRG1/INI1-deficient tumours

(2016) Lien N Hoang et al.   HISTOPATHOLOGY

Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas

(2016) Anthony N Karnezis et al.   MODERN PATHOLOGY

Targeting EZH2 in cancer

(2016) Kimberly H Kim et al.   NATURE MEDICINE

BRG1-deficient dedifferentiated endometrioid adenocarcinoma of the ovary

(2016) Adeline Tan et al.   PATHOLOGY

Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract

(2016) Abbas Agaimy et al.   VIRCHOWS ARCHIV

SMARCA4 (BRG1) Loss of Expression Is a Useful Marker for the Diagnosis of Ovarian Small Cell Carcinoma of the Hypercalcemic Type (Ovarian Rhabdoid Tumor)

(2015) Marie Karanian-Philippe et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Pattern of SMARCB1 (INI1) and SMARCA4 (BRG1) in poorly differentiated endometrioid adenocarcinoma of the uterus: analysis of a series with emphasis on a novel SMARCA4-deficient dedifferentiated rhabdoid variant

(2015) Johanna D. Strehl et al.   Annals of Diagnostic Pathology

SMARCA4/BRG1 Is a Novel Prognostic Biomarker Predictive of Cisplatin-Based Chemotherapy Outcomes in Resected Non-Small Cell Lung Cancer

(2015) E. H. Bell et al.   CLINICAL CANCER RESEARCH

Frequent co-inactivation of the SWI/SNF subunits SMARCB1, SMARCA2 and PBRM1 in malignant rhabdoid tumours

(2015) Qiu Rao et al.   HISTOPATHOLOGY

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type

(2015) Petar Jelinic et al.   MODERN PATHOLOGY

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

(2015) Francois Le Loarer et al.   NATURE GENETICS

SWI/SNF complex deficiency and mismatch repair protein expression in undifferentiated and dedifferentiated endometrial carcinoma

(2015) Colin J.R. Stewart et al.   PATHOLOGY

Frequent loss of the expression of multiple subunits of the SWI/SNF complex in large cell carcinoma and pleomorphic carcinoma of the lung

(2015) Taichiro Yoshimoto et al.   PATHOLOGY INTERNATIONAL

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

(2015) C. Kadoch et al.   Science Advances

The Expanding Family of SMARCB1(INI1)-deficient Neoplasia

(2014) Abbas Agaimy   ADVANCES IN ANATOMIC PATHOLOGY

SMARCB1 (INI1)-negative Rhabdoid Carcinomas of the Gastrointestinal Tract

(2014) Abbas Agaimy et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Flavonoids from each of the six structural groups reactivate BRM, a possible cofactor for the anticancer effects of flavonoids

(2014) Bhaskar Kahali et al.   CARCINOGENESIS

Concurrent loss of INI1, PBRM1, and BRM expression in epithelioid sarcoma: implications for the cocontributions of multiple SWI/SNF complex members to pathogenesis

(2014) Li Li et al.   HUMAN PATHOLOGY

Pancreatic undifferentiated rhabdoid carcinoma: KRAS alterations and SMARCB1 expression status define two subtypes

(2014) Abbas Agaimy et al.   MODERN PATHOLOGY

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

(2014) Pilar Ramos et al.   NATURE GENETICS

Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type

(2014) Leora Witkowski et al.   NATURE GENETICS

Recurrent SMARCA4 mutations in small cell carcinoma of the ovary

(2014) Petar Jelinic et al.   NATURE GENETICS

p40 is the Best Marker for Diagnosing Pulmonary Squamous Cell Carcinoma

(2014) Takahiro Tatsumori et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Right-sided rhabdoid colorectal tumors might be related to the Serrated Pathway

(2013) Massimo Pancione et al.   Diagnostic Pathology

Inactivating Mutations in SWI/SNF Chromatin Remodeling Genes in Human Cancer

(2013) Takahiro Oike et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

(2013) Cigall Kadoch et al.   NATURE GENETICS

Identifying targets for the restoration and reactivation of BRM

(2013) B Kahali et al.   ONCOGENE

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers

(2013) A. Hunter Shain et al.   PLoS One

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features

(2012) Daisuke Matsubara et al.   CANCER SCIENCE

Expression of Squamous Cell Carcinoma Markers and Adenocarcinoma Markers in Primary Pulmonary Neuroendocrine Carcinomas

(2012) Kyohei Masai et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Nonsense Mutation and Inactivation of SMARCA4 (BRG1) in an Atypical Teratoid/Rhabdoid Tumor Showing Retained SMARCB1 (INI1) Expression

(2011) Martin Hasselblatt et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

SOX2 amplification is a common event in squamous cell carcinomas of different organ sites

(2011) Sebastian Maier et al.   HUMAN PATHOLOGY

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategy

(2011) S Gramling et al.   ONCOGENE

Discovery of BRM Targeted Therapies: Novel Reactivation of an Anticancer Gene

(2010) Sarah Gramling et al.   Letters in Drug Design & Discovery

Hybrid Schwannoma/Perineurioma

(2009) Jason L. Hornick et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Genomic Analysis Using High-Density Single Nucleotide Polymorphism-Based Oligonucleotide Arrays and Multiplex Ligation-Dependent Probe Amplification Provides a Comprehensive Analysis of INI1/SMARCB1 in Malignant Rhabdoid Tumors

(2009) E. M. Jackson et al.   CLINICAL CANCER RESEARCH