Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans

Copper at the Fungal Pathogen-Host Axis

(2015) Sarela García-Santamarina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploiting Innate Immune Cell Activation of a Copper-Dependent Antimicrobial Agent during Infection

(2014) Richard A. Festa et al.   CHEMISTRY & BIOLOGY

Iron and copper as virulence modulators in human fungal pathogens

(2014) Chen Ding et al.   MOLECULAR MICROBIOLOGY

Reciprocal functions of Cryptococcus neoformans copper homeostasis machinery during pulmonary infection and meningoencephalitis

(2014) Tian-Shu Sun et al.   Nature Communications

Antifungal Drug Development: Challenges, Unmet Clinical Needs, and New Approaches

(2014) T. Roemer et al.   Cold Spring Harbor Perspectives in Medicine

Cryptococcus neoformans Copper Detoxification Machinery Is Critical for Fungal Virulence

(2013) Chen Ding et al.   Cell Host & Microbe

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal

(2013) A. Loyse et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Robust Affinity Standards for Cu(I) Biochemistry

(2013) Pritha Bagchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of quantitative probes for weaker Cu(i) binding sites completes a set of four capable of detecting Cu(i) affinities from nanomolar to attomolar

(2013) Zhiguang Xiao et al.   Metallomics

A copper hyperaccumulation phenotype correlates with pathogenesis in Cryptococcus neoformans

(2013) Meera R. Raja et al.   Metallomics

Copper in Microbial Pathogenesis: Meddling with the Metal

(2012) Marie I. Samanovic et al.   Cell Host & Microbe

Comparative solution equilibrium studies of anticancer gallium(III) complexes of 8-hydroxyquinoline and hydroxy(thio)pyrone ligands

(2012) Éva A. Enyedy et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Zinc Pyrithione Inhibits Yeast Growth through Copper Influx and Inactivation of Iron-Sulfur Proteins

(2011) Nancy L. Reeder et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata

(2011) Simona Maria Monti et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Adaptation of Cryptococcus neoformans to Mammalian Hosts: Integrated Regulation of Metabolism and Virulence

(2011) Jim Kronstad et al.   EUKARYOTIC CELL

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The copper regulon of the human fungal pathogen Cryptococcus neoformans H99

(2011) Chen Ding et al.   MOLECULAR MICROBIOLOGY

Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box

(2011) James W. Kronstad et al.   NATURE REVIEWS MICROBIOLOGY

Quinoline-Based Antifungals

(2010) R. Musiol et al.   CURRENT MEDICINAL CHEMISTRY

Lipophilicity of kinetically labile metal complexes through the example of antidiabetic Zn(II) and VO(IV) compounds

(2010) Éva A. Enyedy et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The challenges of determining metal–protein affinities

(2010) Zhiguang Xiao et al.   NATURAL PRODUCT REPORTS

Affinity gradients drive copper to cellular destinations

(2010) Lucia Banci et al.   NATURE

Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

(2010) Edward Sionov et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Role of Ferroxidases in Iron Uptake and Virulence ofCryptococcus neoformans

(2009) Won Hee Jung et al.   EUKARYOTIC CELL

Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn(ii) and Mo(vi). Thermodynamic stability and insulin-mimetic activity

(2009) Sílvia Chaves et al.   Metallomics

Unexpected C−H Activation of Ru(II)−Dithiomaltol Complexes upon Oxidation

(2008) Malin Backlund et al.   INORGANIC CHEMISTRY

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON

Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans

(2008) Won Hee Jung et al.   PLoS Pathogens