Metabolomics based markers predict type 2 diabetes in a 14-year follow-up study

Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS

(2016) Yonghai Lu et al.   DIABETOLOGIA

Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients

(2016) Hannah Mathew et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Association of Metabolites with Obesity and Type 2 Diabetes Based on FTO Genotype

(2016) Yeon-Jung Kim et al.   PLoS One

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control

(2015) Noha A. Yousri et al.   DIABETOLOGIA

Plasma metabolomic profiles in association with type 2 diabetes risk and prevalence in Chinese adults

(2015) Danxia Yu et al.   Metabolomics

A Metabolomic Approach to Understanding the Metabolic Link between Obesity and Diabetes

(2015) Seokjae Park et al.   MOLECULES AND CELLS

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

(2015) Harmen H. M. Draisma et al.   Nature Communications

Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses

(2015) Ayşe Demirkan et al.   PLoS Genetics

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Early Improvement Predicts Reduced Risk of Incident Diabetes and Improved Cardiovascular Risk in Prediabetic Asian Indian Men Participating in a 2-Year Lifestyle Intervention Program

(2014) Arun Nanditha et al.   DIABETES CARE

Metabolite Traits and Genetic Risk Provide Complementary Information for the Prediction of Future Type 2 Diabetes

(2014) Geoffrey A. Walford et al.   DIABETES CARE

Molecular phenotyping of a UK population: defining the human serum metabolome

(2014) Warwick B. Dunn et al.   Metabolomics

Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

(2014) Michael Lever et al.   PLoS One

Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up

(2014) D. O. Mook-Kanamori et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Lipidomics of familial longevity

(2013) Vanessa Gonzalez-Covarrubias et al.   AGING CELL

Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models

(2013) Andre Pascal Kengne et al.   Lancet Diabetes & Endocrinology

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach

(2012) A. Floegel et al.   DIABETES

Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

(2012) E. Ferrannini et al.   DIABETES

Association of Weight Status With Mortality in Adults With Incident Diabetes

(2012) Mercedes R. Carnethon et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Serum Metabolic Signatures of Fulminant Type 1 Diabetes

(2012) Jingyi Lu et al.   JOURNAL OF PROTEOME RESEARCH

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

MetaboLights—an open-access general-purpose repository for metabolomics studies and associated meta-data

(2012) Kenneth Haug et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

(2012) Ayşe Demirkan et al.   PLoS Genetics

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models

(2011) Michael J. Pencina et al.   STATISTICS IN MEDICINE

Cost-Effectiveness of Interventions to Prevent and Control Diabetes Mellitus: A Systematic Review

(2010) R. Li et al.   DIABETES CARE

The Leicester Risk Assessment score for detecting undiagnosed Type 2 diabetes and impaired glucose regulation for use in a multiethnic UK setting

(2010) L. J. Gray et al.   DIABETIC MEDICINE

α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population

(2010) Walter E. Gall et al.   PLoS One

Metabolic Footprint of Diabetes: A Multiplatform Metabolomics Study in an Epidemiological Setting

(2010) Karsten Suhre et al.   PLoS One

Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations

(2009) A. Kotronen et al.   DIABETOLOGIA

Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study

(2009) Adam G Tabák et al.   LANCET

Does serum 1,5-anhydroglucitol establish a relationship between improvements in HbA1cand postprandial glucose excursions? Supportive evidence utilizing the differential effects between biphasic insulin aspart 30 and insulin glargine

(2008) A. C. Moses et al.   DIABETIC MEDICINE

RPLC-Ion-Trap-FTMS Method for Lipid Profiling of Plasma: Method Validation and Application to p53 Mutant Mouse Model

(2008) Chunxiu Hu et al.   JOURNAL OF PROTEOME RESEARCH

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

(2008) Oded Shaham et al.   Molecular Systems Biology

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS