Synthesis, spectral characterization, DNA binding ability and anti-cancer screening of new acridine-based derivatives

New spiro tria(thia)zolidine⿿acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

(2016) Othman M. Salem et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors

(2015) Jana Janočková et al.   BIOORGANIC CHEMISTRY

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds

(2015) Jana Janočková et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Strong deshielding in aromatic isoxazolines

(2015) Lucia Ungvarská Maľučká et al.   MAGNETIC RESONANCE IN CHEMISTRY

Prediction by13C NMR of regioselectivity in 1,3-dipolar cycloadditions of acridin-9-yl dipolarophiles

(2015) Mária Vilková et al.   MAGNETIC RESONANCE IN CHEMISTRY

Interaction of 6 Mercaptopurine with Calf Thymus DNA – Deciphering the Binding Mode and Photoinduced DNA Damage

(2014) Sayeed Ur Rehman et al.   PLoS One

Novel synthetic acridine derivatives as potent DNA-binding and apoptosis-inducing antitumor agents

(2013) Xuliang Lang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

DNA interaction of CuII, NiII and ZnII functionalized salphen complexes: studies by linear dichroism, gel electrophoresis and PCR

(2013) Alessio Terenzi et al.   DALTON TRANSACTIONS

Synthesis, DNA Binding and Topoisomerase I Inhibition Activity of Thiazacridine and Imidazacridine Derivatives

(2013) Elizabeth Lafayette et al.   MOLECULES

Single-molecule FRET and linear dichroism studies of DNA breathing and helicase binding at replication fork junctions

(2013) C. Phelps et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of DNA topoisomerase I activity and induction of apoptosis by thiazacridine derivatives

(2013) Francisco W.A. Barros et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Synthesis and cytotoxic activity of new acridine-thiazolidine derivatives

(2012) Francisco W.A. Barros et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Influence of carboxylic acid functionalities in ruthenium (II) polypyridyl complexes on DNA binding, cytotoxicity and antioxidant activity: Synthesis, structure and in vitro anticancer activity

(2012) Thangavel Sathiya Kamatchi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Topoisomerase 1 Inhibitors and Cancer Therapy

(2012) Julia Moukharskaya et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Non-intercalative binding mode of bridged binuclear chiral Ru(II) complexes to native duplex DNA

(2011) Nataraj Chitrapriya et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

All tangled up: how cells direct, manage and exploit topoisomerase function

(2011) Seychelle M. Vos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mesomorphic behaviour of N-benzoyl-N′-aryl thioureas liquid crystalline compounds

(2010) Monica Iliş et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis and structure–activity relationships of amide derivatives of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetic acid as selective arginine vasopressin V2 receptor agonists

(2009) Issei Tsukamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cytotoxic activity of acridin-3,6-diyl dithiourea hydrochlorides in human leukemia line HL-60 and resistant subline HL-60/ADR

(2009) Zuzana Vantová et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Spectroscopic studies on the interaction of pazufloxacin with calf thymus DNA

(2008) Xia Ling et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Studies on the interaction of isoxazolcurcumin with calf thymus DNA

(2007) Rabindranath Bera et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Acridine-Based Agents with Topoisomerase II Activity Inhibit Pancreatic Cancer Cell Proliferation and Induce Apoptosis

(2007) John R. Goodell et al.   JOURNAL OF MEDICINAL CHEMISTRY

DNA-damaging activity and mutagenicity of 16 newly synthesized thiazolo[5,4-a]acridine derivatives with high photo-inducible cytotoxicity

(2007) Carole Di Giorgio et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS