Journal
MATERIALS LETTERS
Volume 209, Issue -, Pages 295-298Publisher
ELSEVIER
DOI: 10.1016/j.matlet.2017.08.030
Keywords
Amaranthus caudatus; SEM-EDX mapping; Zinc oxide nanoparticles (ZnONPs); Zebrafish; Toxicity; Diabetes mellitus
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In the present study zinc oxide nanoparticles (ZnONPs) were synthesized by the extract of the plant, Amaranthus caudatus. ZnONPs were characterized by FTIR and SEM coupled with EDX. Among the various concentrations of ZnONPs administered, 10 mg/ml or more caused deformities and less survival rate. ZnONPs were found to influence the normal development of zebrafish embryos in a dose dependent manner. The ZnONPs were found to exhibit anti-bacterial activity; the activity was more towards Gram positive bacteria (S. epidermidis) than the Gram negative bacteria (E. aerogenes). The low concentrations of ZnONPs could be used as a therapeutic agent for diabetes mellitus. (C) 2017 Elsevier B.V. All rights reserved.
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