Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking Water
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Title
Cyanobacterial Toxins of the Laurentian Great Lakes, Their Toxicological Effects, and Numerical Limits in Drinking Water
Authors
Keywords
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Journal
Marine Drugs
Volume 15, Issue 6, Pages 160
Publisher
MDPI AG
Online
2017-06-02
DOI
10.3390/md15060160
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Note: Only part of the references are listed.- Variable Cyanobacterial Toxin and Metabolite Profiles across Six Eutrophic Lakes of Differing Physiochemical Characteristics
- (2017) Lucas Beversdorf et al. Toxins
- Involvement of oxidative stress and cytoskeletal disruption in microcystin-induced apoptosis in CIK cells
- (2015) Xiao Huang et al. AQUATIC TOXICOLOGY
- Microcystin-LR impairs zebrafish reproduction by affecting oogenesis and endocrine system
- (2015) Yanyan Zhao et al. CHEMOSPHERE
- Competition between toxic and non-toxic Microcystis aeruginosa and its ecological implication
- (2015) Lamei Lei et al. ECOTOXICOLOGY
- Duelling ‘CyanoHABs’: unravelling the environmental drivers controlling dominance and succession among diazotrophic and non-N2 -fixing harmful cyanobacteria
- (2015) Hans W. Paerl et al. ENVIRONMENTAL MICROBIOLOGY
- Effects of Increasing Nitrogen and Phosphorus Concentrations on Phytoplankton Community Growth and Toxicity During Planktothrix Blooms in Sandusky Bay, Lake Erie
- (2015) Timothy W. Davis et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Relative importance ofMicrocystisabundance and diversity in determining microcystin dynamics in Lake Erie coastal wetland and downstream beach water
- (2015) C. Hu et al. JOURNAL OF APPLIED MICROBIOLOGY
- Different tolerances to chemical contaminants between unicellular and colonial morph of Microcystis aeruginosa: Excluding the differences among different strains
- (2015) Ming Li et al. JOURNAL OF HAZARDOUS MATERIALS
- Genetic Polymorphisms and Function of the Organic Anion-Transporting Polypeptide 1A2 and Its Clinical Relevance in Drug Disposition
- (2015) Yinhui Zhou et al. PHARMACOLOGY
- The role of PP2A-associated proteins and signal pathways in microcystin-LR toxicity
- (2015) Jing Liu et al. TOXICOLOGY LETTERS
- Mechanisms of microcystin-LR-induced cytoskeletal disruption in animal cells
- (2015) Mi Zhou et al. TOXICON
- PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects
- (2015) Raúl Rincón et al. Oncotarget
- Microcystin mcyA and mcyE Gene Abundances Are Not Appropriate Indicators of Microcystin Concentrations in Lakes
- (2015) Lucas J. Beversdorf et al. PLoS One
- Diversity of toxin and non-toxin containing cyanobacterial mats of meltwater ponds on the Antarctic Peninsula: a pyrosequencing approach
- (2014) J. Kleinteich et al. ANTARCTIC SCIENCE
- Molecular effects of the cyanobacterial toxin cyanopeptolin (CP1020) occurring in algal blooms: Global transcriptome analysis in zebrafish embryos
- (2014) Susanne Faltermann et al. AQUATIC TOXICOLOGY
- Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria
- (2014) Alexandra Calteau et al. BMC GENOMICS
- Regulation of Microcystin-LR-Induced Toxicity in Mouse Spermatogonia by miR-96
- (2014) Yuan Zhou et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Alterations in neurobehaviors and inflammation in hippocampus of rats induced by oral administration of microcystin-LR
- (2014) Xiao-Bo Li et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Maternal repeated oral exposure to microcystin-LR affects neurobehaviors in developing rats
- (2014) XiaoBo Li et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Evidence for oxygenic photosynthesis half a billion years before the Great Oxidation Event
- (2014) Noah J. Planavsky et al. Nature Geoscience
- Selectivity and Potency of Microcystin Congeners against OATP1B1 and OATP1B3 Expressing Cancer Cells
- (2014) Timo H. J. Niedermeyer et al. PLoS One
- Origin and Evolution of Plastids and Photosynthesis in Eukaryotes
- (2014) G. I. McFadden Cold Spring Harbor Perspectives in Biology
- Freshwater Harmful Algal Blooms: Toxins and Children's Health
- (2014) Chelsea A. Weirich et al. Current Problems in Pediatric and Adolescent Health Care
- Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
- (2013) Parthasarathy Seshacharyulu et al. CANCER LETTERS
- Potent toxins in Arctic environments – Presence of saxitoxins and an unusual microcystin variant in Arctic freshwater ecosystems
- (2013) Julia Kleinteich et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Microcystin-LR inhibited hippocampal long-term potential via regulation of the glycogen synthase kinase-3β pathway
- (2013) Jianghua Wang et al. CHEMOSPHERE
- Toxin-producing cyanobacteria in freshwater: A review of the problems, impact on drinking water safety, and efforts for protecting public health
- (2013) Melissa Y. Cheung et al. JOURNAL OF MICROBIOLOGY
- Protein phosphatase 2A: a target for anticancer therapy
- (2013) Danilo Perrotti et al. LANCET ONCOLOGY
- Diversity of cyanobacteria and cyanotoxins in Hartbeespoort Dam, South Africa
- (2013) Andreas Ballot et al. MARINE AND FRESHWATER RESEARCH
- Magnetic Resonance Imaging for Rapid Screening for the Nephrotoxic and Hepatotoxic Effects of Microcystins
- (2013) Aleksandra Milutinović et al. Marine Drugs
- The Role of Nitrogen Fixation in Cyanobacterial Bloom Toxicity in a Temperate, Eutrophic Lake
- (2013) Lucas J. Beversdorf et al. PLoS One
- Spatiotemporal Molecular Analysis of Cyanobacteria Blooms Reveals Microcystis-Aphanizomenon Interactions
- (2013) Todd R. Miller et al. PLoS One
- Linking β-methylamino-l-alanine exposure to sporadic amyotrophic lateral sclerosis in Annapolis, MD
- (2013) Nicholas C. Field et al. TOXICON
- Localization of pufferfish saxitoxin and tetrodotoxin binding protein (PSTBP) in the tissues of the pufferfish, Takifugu pardalis, analyzed by immunohistochemical staining
- (2013) Mari Yotsu-Yamashita et al. TOXICON
- Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1
- (2013) Anne T Nies et al. Genome Medicine
- Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes
- (2013) Kumiko Shimizu et al. Toxins
- Risk Assessment of Shellfish Toxins
- (2013) Rex Munday et al. Toxins
- Selective LC-MS/MS method for the identification of BMAA from its isomers in biological samples
- (2012) Liying Jiang et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Toxic effects of microcystin-LR on the reproductive system of male Rana nigromaculata in vitro
- (2012) Hangjun Zhang et al. AQUATIC TOXICOLOGY
- Thiol Derivatization for LC-MS Identification of Microcystins in Complex Matrices
- (2012) Christopher O. Miles et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Spatial learning and memory impairment and pathological change in rats induced by acute exposure to microcystin-LR
- (2012) Guangyu Li et al. ENVIRONMENTAL TOXICOLOGY
- Characterization of paralytic shellfish toxins from Lyngbya wollei dominated mats collected from two Florida springs
- (2012) Amanda J. Foss et al. HARMFUL ALGAE
- Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data
- (2012) Jun Li et al. JOURNAL OF SEPARATION SCIENCE
- A Comparative Study on Three Analytical Methods for the Determination of the Neurotoxin BMAA in Cyanobacteria
- (2012) Elisabeth J. Faassen et al. PLoS One
- Interannual Variability of Cyanobacterial Blooms in Lake Erie
- (2012) Richard P. Stumpf et al. PLoS One
- Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis
- (2012) U. Kaasalainen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human and rat hepatocyte toxicity and protein phosphatase 1 and 2A inhibitory activity of naturally occurring desmethyl-microcystins and nodularins
- (2012) Helena Ufelmann et al. TOXICOLOGY
- The toxic effects of microcystin-LR on rat spermatogonia in vitro
- (2012) Yuan Zhou et al. TOXICOLOGY LETTERS
- The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in Cancer
- (2011) Amanda Obaidat et al. Annual Review of Pharmacology and Toxicology
- Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line
- (2011) Alja Štraser et al. ARCHIVES OF TOXICOLOGY
- PP2A targeting by viral proteins: A widespread biological strategy from DNA/RNA tumor viruses to HIV-1
- (2011) Julien Guergnon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression
- (2011) C. M. Lucas et al. BLOOD
- Microcystin-LR acute exposure increases AChE activity via transcriptional ache activation in zebrafish (Danio rerio) brain
- (2011) Luiza Wilges Kist et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
- Occurrence of diarrhetic shellfish poisoning (DSP) toxins in clams (Ruditapes decussatus) from Tunis north lagoon
- (2011) Zina Armi et al. ENVIRONMENTAL MONITORING AND ASSESSMENT
- Microcystin–LR causes cytotoxicity effects in rat testicular Sertoli cells
- (2011) Yan Li et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Quantitative determination of marine lipophilic toxins in mussels, oysters and cockles using liquid chromatography-mass spectrometry: inter-laboratory validation study
- (2011) H.J. van den Top et al. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment
- Cyanobacteria: an emerging source for drug discovery
- (2011) Rahul Kunwar Singh et al. JOURNAL OF ANTIBIOTICS
- Verification and quantification of saxitoxin from algal samples using fast and validated hydrophilic interaction liquid chromatography–tandem mass spectrometry method
- (2011) Mia Halme et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- From River to Lake: Phosphorus partitioning and algal community compositional changes in Western Lake Erie
- (2011) Thomas B. Bridgeman et al. JOURNAL OF GREAT LAKES RESEARCH
- INVOLVEMENT OF MICROCYSTINS AND COLONY SIZE IN THE BENTHIC RECRUITMENT OF THE CYANOBACTERIUM MICROCYSTIS (CYANOPHYCEAE)1
- (2011) Benjamin Misson et al. JOURNAL OF PHYCOLOGY
- Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake
- (2011) M. Niemi et al. PHARMACOLOGICAL REVIEWS
- Discovery of Nuclear-Encoded Genes for the Neurotoxin Saxitoxin in Dinoflagellates
- (2011) Anke Stüken et al. PLoS One
- The proteomic study on cellular responses of the testes of zebrafish (Danio rerio) exposed to microcystin-RR
- (2011) Sujuan Zhao et al. PROTEOMICS
- Decline of sperm quality and testicular function in male mice during chronic low-dose exposure to microcystin-LR
- (2011) Yu Chen et al. REPRODUCTIVE TOXICOLOGY
- A Cyanobacterial Toxin, Microcystin-LR, Induces Apoptosis of Sertoli Cells by Changing the Expression Levels of Apoptosis-Related Proteins
- (2011) Hui-Zhen Zhang et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Similar uptake profiles of microcystin-LR and -RR in an in vitro human intestinal model
- (2011) P. Zeller et al. TOXICOLOGY
- Microcystin (-LR) affects hormones level of male mice by damaging hypothalamic-pituitary system
- (2011) Xueting Wang et al. TOXICON
- Toxic cyanobacterial breakthrough and accumulation in a drinking water plant: A monitoring and treatment challenge
- (2011) Arash Zamyadi et al. WATER RESEARCH
- Increased incidence of Cylindrospermopsis raciborskii in temperate zones – Is climate change responsible?
- (2011) Rati Sinha et al. WATER RESEARCH
- Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels
- (2011) Marijke Stevens et al. Frontiers in Pharmacology
- A review of cyanobacteria and cyanotoxins removal/inactivation in drinking water treatment
- (2010) Judy A. Westrick et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Detection of Saxitoxin-Producing Cyanobacteria and Anabaena circinalis in Environmental Water Blooms by Quantitative PCR
- (2010) J. Al-Tebrineh et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Paralytic Shellfish Poisoning Toxin-Producing Cyanobacterium Aphanizomenon gracile in Northeast Germany
- (2010) A. Ballot et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Protein kinase C regulates the internalization and function of the human organic anion transporting polypeptide 1A2
- (2010) Fanfan Zhou et al. BRITISH JOURNAL OF PHARMACOLOGY
- Calcifying cyanobacteria—the potential of biomineralization for carbon capture and storage
- (2010) Christer Jansson et al. CURRENT OPINION IN BIOTECHNOLOGY
- Spatial and temporal distribution of the cyanotoxin microcystin-LR in the Lake Ontario ecosystem: Coastal embayments, rivers, nearshore and offshore, and upland lakes
- (2010) Joseph C. Makarewicz et al. JOURNAL OF GREAT LAKES RESEARCH
- Lyngbya wollei in western Lake Erie
- (2010) Thomas B. Bridgeman et al. JOURNAL OF GREAT LAKES RESEARCH
- Multiple Toxin Production in the CyanobacteriumMicrocystis: Isolation of the Toxic Protease Inhibitor Cyanopeptolin 1020
- (2010) Karl Gademann et al. JOURNAL OF NATURAL PRODUCTS
- Cyanobacterial neurotoxin BMAA in ALS and Alzheimer’s disease
- (2009) J. Pablo et al. ACTA NEUROLOGICA SCANDINAVICA
- Spatial and temporal variation in microcystin concentrations during perennial bloom of Planktothrix agardhii in a hypertrophic lake
- (2009) B. Pawlik-Skowrońska et al. ANNALES DE LIMNOLOGIE-INTERNATIONAL JOURNAL OF LIMNOLOGY
- Late-summer phytoplankton in western Lake Erie (Laurentian Great Lakes): bloom distributions, toxicity, and environmental influences
- (2009) David F. Millie et al. AQUATIC ECOLOGY
- CIP2A Is Associated with Human Breast Cancer Aggressivity
- (2009) C. Come et al. CLINICAL CANCER RESEARCH
- Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier
- (2009) A. Ose et al. DRUG METABOLISM AND DISPOSITION
- Accumulation of microcystins in water and fish tissues: An estimation of risks associated with microcystins in most of the Greek Lakes
- (2009) Theodoti Papadimitriou et al. ENVIRONMENTAL TOXICOLOGY
- Raphidiopsis mediterranea Skuja represents non-heterocytous life-cycle stages of Cylindrospermopsis raciborskii (Woloszynska) Seenayya et Subba Raju in Lake Kastoria (Greece), its type locality: Evidence by morphological and phylogenetic analysis
- (2009) Maria Moustaka-Gouni et al. HARMFUL ALGAE
- Lake Erie Microcystis: Relationship between microcystin production, dynamics of genotypes and environmental parameters in a large lake
- (2009) Johanna M. Rinta-Kanto et al. HARMFUL ALGAE
- Effects of Light and Wind Speed on the Vertical Distribution ofMicrocystis aeruginosaColonies of Different Sizes during a Summer Bloom
- (2009) Xiaodong Wu et al. INTERNATIONAL REVIEW OF HYDROBIOLOGY
- Pharmacogenetics of the organic anion transporting polypeptide 1A2
- (2009) Ryan M Franke et al. PHARMACOGENOMICS
- Involvement of Fas/FasL system in apoptotic signaling in testicular germ cells of male Wistar rats injected i.v. with microcystins
- (2009) Qian Xiong et al. TOXICON
- Detection of the neurotoxin BMAA within cyanobacteria isolated from freshwater in China
- (2009) Aifeng Li et al. TOXICON
- Neurotoxic cyanobacterial toxins
- (2009) Rómulo Aráoz et al. TOXICON
- Detection and quantification of Microcystis spp. and microcystin-LR in Western Lake Erie during the summer of 2007
- (2009) Hui Wang et al. WATER SCIENCE AND TECHNOLOGY
- Determination of the neurotoxin BMAA (β-N-methylamino-l-alanine) in cycad seed and cyanobacteria by LC-MS/MS (liquid chromatography tandem mass spectrometry)
- (2008) Johan Rosén et al. ANALYST
- Protein phosphatase 2A (PP2A), a drugable tumor suppressor in Ph1(+) leukemias
- (2008) Danilo Perrotti et al. CANCER AND METASTASIS REVIEWS
- Microcystin concentrations and genetic diversity ofMicrocystisin the lower Great Lakes
- (2008) Julianne Dyble et al. ENVIRONMENTAL TOXICOLOGY
- Spatial and temporal diversity of microcystins and microcystin-producing genotypes in Oneida Lake, NY
- (2008) Amber M. Hotto et al. HARMFUL ALGAE
- Abundance and toxicity of Planktothrix rubescens in the pre-alpine Lake Ammersee, Germany
- (2008) Bernhard Ernst et al. HARMFUL ALGAE
- The diversity and distribution of toxigenic Microcystis spp. in present day and archived pelagic and sediment samples from Lake Erie
- (2008) Johanna M. Rinta-Kanto et al. HARMFUL ALGAE
- Cyanobacteria (Nostoc commune) used as a dietary item in the Peruvian highlands produce the neurotoxic amino acid BMAA
- (2008) Holly E. Johnson et al. JOURNAL OF ETHNOPHARMACOLOGY
- Estimated daily average per capita water ingestion by child and adult age categories based on USDA's 1994–1996 and 1998 continuing survey of food intakes by individuals
- (2008) Henry D Kahn et al. Journal of Exposure Science and Environmental Epidemiology
- Non-Traditional Vectors for Paralytic Shellfish Poisoning
- (2008) Jonathan Deeds et al. Marine Drugs
- Oatp-associated uptake and toxicity of microcystins in primary murine whole brain cells
- (2008) D. Feurstein et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
- (2008) B. Hagenbuch et al. XENOBIOTICA
- Toxic Alcohol Ingestions: Clinical Features, Diagnosis, and Management
- (2007) J. A. Kraut et al. Clinical Journal of the American Society of Nephrology
- Dose-dependent effects of extracted microcystins on embryonic development, larval growth and histopathological changes of southern catfish (Silurus meridionalis)
- (2007) Xuezhen Zhang et al. TOXICON
- Interaction of the cyanobacterial toxin cylindrospermopsin with the eukaryotic protein synthesis system
- (2007) S.M. Froscio et al. TOXICON
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