A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

Acute Myeloid Leukemia, Version 2.2013

(2017) Margaret R. O’Donnell et al.   Journal of the National Comprehensive Cancer Network

Cooperative Action between SALL4A and TET Proteins in Stepwise Oxidation of 5-Methylcytosine

(2016) Jun Xiong et al.   MOLECULAR CELL

Long noncoding RNAs in DNA methylation: new players stepping into the old game

(2016) Yu Zhao et al.   Cell and Bioscience

Aberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein–Barr virus-associated gastric carcinomas

(2015) Dan He et al.   MEDICAL ONCOLOGY

WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation

(2015) Yiping Wang et al.   MOLECULAR CELL

Insulator dysfunction and oncogene activation in IDH mutant gliomas

(2015) William A. Flavahan et al.   NATURE

Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition

(2014) S. Sinha et al.   BLOOD

Characterization of acute myeloid leukemia based on levels of global hydroxymethylation

(2014) L. I. Kroeze et al.   BLOOD

Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma

(2014) T. Tahara et al.   CANCER RESEARCH

CpG Island Methylator Phenotype Is Associated With Response to Adjuvant Irinotecan-Based Therapy for Stage III Colon Cancer

(2014) Stacey Shiovitz et al.   GASTROENTEROLOGY

TET2mutations in cytogenetically normal acute myeloid leukemia: Clinical implications and evolutionary patterns

(2014) Frederik Damm et al.   GENES CHROMOSOMES & CANCER

Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue

(2014) Troy D. Dumenil et al.   GENES CHROMOSOMES & CANCER

Age-related epigenetic drift in the pathogenesis of MDS and AML

(2014) S. Maegawa et al.   GENOME RESEARCH

TET2 gene mutation is unfavorable prognostic factor in cytogenetically normal acute myeloid leukemia patients with NPM1+ and FLT3-ITD− mutations

(2014) Xiaopeng Tian et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Association between DNMT3A Mutations and Prognosis of Adults with De Novo Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis

(2014) Ruxiu Tie et al.   PLoS One

DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

(2014) Raajit Rampal et al.   Cell Reports

Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score

(2013) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells

(2013) Bruno Di Stefano et al.   NATURE

DNMT1-interacting RNAs block gene-specific DNA methylation

(2013) Annalisa Di Ruscio et al.   NATURE

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

(2012) Pierre Bady et al.   ACTA NEUROPATHOLOGICA

Conserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique

(2012) Jaroslav Jelinek et al.   Epigenetics

Decreased DNA methylation in acute myeloid leukemia patients with DNMT3A mutations and prognostic implications of DNA methylation

(2012) Hana Hájková et al.   LEUKEMIA RESEARCH

Tet2 Facilitates the Derepression of Myeloid Target Genes during CEBPα-Induced Transdifferentiation of Pre-B Cells

(2012) Eric M. Kallin et al.   MOLECULAR CELL

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Methylation profile of triple-negative breast carcinomas

(2012) M T Branham et al.   Oncogenesis

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study

(2011) E. A. Coenen et al.   BLOOD

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

(2011) Wei Xu et al.   CANCER CELL

RUNX1 Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group

(2011) Verena I. Gaidzik et al.   JOURNAL OF CLINICAL ONCOLOGY

The Global DNA Methylation Surrogate LINE-1 Methylation Is Correlated with MGMT Promoter Methylation and Is a Better Prognostic Factor for Glioma

(2011) Fumiharu Ohka et al.   PLoS One

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis

(2011) F. Fang et al.   Science Translational Medicine

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia

(2010) H. J. M. de Jonge et al.   BLOOD

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

(2010) Patrick S. Ward et al.   CANCER CELL

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

(2010) Maria E. Figueroa et al.   CANCER CELL

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers

(2010) Byonggu An et al.   INTERNATIONAL JOURNAL OF CANCER

Three DNA Methylation Epigenotypes in Human Colorectal Cancer

(2009) K. Yagi et al.   CLINICAL CANCER RESEARCH

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse

(2008) H. Kroeger et al.   BLOOD

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Monosomal Karyotype in Acute Myeloid Leukemia: A Better Indicator of Poor Prognosis Than a Complex Karyotype

(2008) Dimitri A. Breems et al.   JOURNAL OF CLINICAL ONCOLOGY

Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia

(2008) Richard F. Schlenk et al.   NEW ENGLAND JOURNAL OF MEDICINE