Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth

Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells

(2016) Yujie Zhao et al.   Oncotarget

Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy

(2014) Ming-Hui Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine attenuates high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells: Involvement of suppression of cell cycle progression and NF-κB/AP-1 pathways

(2014) Tian Lan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Matrine inhibits proliferation and induces apoptosis via BID-mediated mitochondrial pathway in esophageal cancer cells

(2014) Qiao Wang et al.   MOLECULAR BIOLOGY REPORTS

Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice

(2014) Weidong Li et al.   MOLECULAR CARCINOGENESIS

Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium-Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-κB Activation

(2014) Juan Li et al.   PLoS One

Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

(2013) Junfang Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Berberine Inhibits Proliferation and Down-Regulates Epidermal Growth Factor Receptor through Activation of Cbl in Colon Tumor Cells

(2013) Lihong Wang et al.   PLoS One

The tumor-suppressor gene Nkx2.8 suppresses bladder cancer proliferation through upregulation of FOXO3a and inhibition of the MEK/ERK signaling pathway

(2012) Chunping Yu et al.   CARCINOGENESIS

The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells

(2012) Kotamballi N. Chidambara Murthy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

(2012) Lihong Wang et al.   PLoS One

Molecular Pathways Underlying IBD-Associated Colorectal Neoplasia: Therapeutic Implications

(2011) Gati A Goel et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice

(2011) Fang Yan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia

(2011) Ai-Wen Feng et al.   FITOTERAPIA

Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis

(2011) Xuan Xia et al.   PLoS One

Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-κB activation

(2010) In-Ah Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: Involvement of NF-κB signaling pathway

(2010) Qin Jiang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs

(2009) Yiyi Sun et al.   ANTI-CANCER DRUGS

Berberine Differentially Modulates the Activities of ERK, p38 MAPK, and JNK to Suppress Th17 and Th1 T Cell Differentiation in Type 1 Diabetic Mice

(2009) Guoliang Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional use and biomedical investigations

(2009) Jun Tang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bid exhibits S phase checkpoint activation and plays a pro-apoptotic role in response to etoposide-induced DNA damage in hepatocellular carcinoma cells

(2008) Gang Song et al.   APOPTOSIS

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1α up-regulation and MMP9 activation

(2008) Gang Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE