Molecular Pathways Underlying IBD-Associated Colorectal Neoplasia: Therapeutic Implications

Cancer colorectaux métastatiques et thérapies ciblées anti-EGFR

(2011) Frédéric Viret et al.   M S-MEDECINE SCIENCES

The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia

(2010) Yasmin Hernandez et al.   BMC GASTROENTEROLOGY

Matrix Metalloproteinase-9 Functions as a Tumor Suppressor in Colitis-Associated Cancer

(2010) P. Garg et al.   CANCER RESEARCH

The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon

(2010) D. Mladenova et al.   GUT

Anti-carcinogenic properties of curcumin on colorectal cancer

(2010) Jung Park   World Journal of Gastrointestinal Oncology

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

(2009) Pallavi Garg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Blockade of a Chemokine, CCL2, Reduces Chronic Colitis-Associated Carcinogenesis in Mice

(2009) B. K. Popivanova et al.   CANCER RESEARCH

PC-407, a celecoxib derivative, inhibited the growth of colorectal tumorin vitroandin vivo

(2009) Yuhua Li et al.   CANCER SCIENCE

5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model

(2009) P. J. Koelink et al.   CARCINOGENESIS

Curcumin has Bright Prospects for the Treatment of Inflammatory Bowel Disease

(2009) Hiroyuki Hanai et al.   CURRENT PHARMACEUTICAL DESIGN

Mesalamine Inhibits Epithelial β-Catenin Activation in Chronic Ulcerative Colitis

(2009) Jeffrey B. Brown et al.   GASTROENTEROLOGY

Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis

(2009) Y. Li et al.   GUT

Mesalamine Suppresses the Expression of TC22, a Novel Tropomyosin Isoform Associated with Colonic Neoplasia

(2009) K. K. Das et al.   MOLECULAR PHARMACOLOGY

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility

(2009) Joshua M. Uronis et al.   PLoS One

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

(2008) G. Y. Chen et al.   CANCER RESEARCH

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

Aberrant Crypt Foci as Precursors of the Dysplasia-Carcinoma Sequence in Patients with Ulcerative Colitis

(2008) T. Kukitsu et al.   CLINICAL CANCER RESEARCH

Progression to Colorectal Neoplasia in Ulcerative Colitis: Effect of Mesalamine

(2008) Thomas Ullman et al.   Clinical Gastroenterology and Hepatology

Ulcerative Colitis-Associated Colorectal Cancer is Frequently Associated with the Microsatellite Instability Pathway

(2008) Ichiro Fujiwara et al.   DISEASES OF THE COLON & RECTUM

Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

(2008) Simon J. Leedham et al.   GASTROENTEROLOGY

Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis

(2008) K Assi et al.   GUT

High frequency of early colorectal cancer in inflammatory bowel disease

(2008) M W M D Lutgens et al.   GUT

A component of polysaccharide peptidoglycan complex onLactobacillusinduced an improvement of murine model of inflammatory bowel disease and colitis-associated cancer

(2008) S. Matsumoto et al.   IMMUNOLOGY

Disease modifying effect of statins in dextran sulfate sodium model of mouse colitis

(2008) N. Kanagarajan et al.   INFLAMMATION RESEARCH

Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease

(2008) Michael A. Manfredi et al.   INFLAMMATORY BOWEL DISEASES

Two distinct groups of colorectal cancer in inflammatory bowel disease

(2008) Stephan Brackmann et al.   INFLAMMATORY BOWEL DISEASES

Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia

(2008) Mashaal Dhir et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer

(2008) Robert S. Chapkin et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Increased susceptibility of chronic ulcerative colitis‐induced carcinoma development in DNA repair enzymeOgg1deficient mice

(2008) Jie Liao et al.   MOLECULAR CARCINOGENESIS

Effects of nimesulide, a cyclooxygenase-2 selective inhibitor, on colitis induced tumors

(2008) T. Inoue et al.   INFLAMMOPHARMACOLOGY

Association of hyperhomocysteinemia and folate deficiency with colon tumors in patients with inflammatory bowel disease

(2007) Jean Marc Phelip et al.   INFLAMMATORY BOWEL DISEASES