Spleen-derived lipocalin-2 in the portal vein regulates Kupffer cells activation and attenuates the development of liver fibrosis in mice

Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation

(2015) M. I. Ashraf et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: A critical role for IL-6/STAT3

(2015) Ming-Jiang Xu et al.   HEPATOLOGY

Splenectomy attenuates murine liver fibrosis with hypersplenism stimulating hepatic accumulation of Ly-6Clo macrophages

(2015) Akito Yada et al.   JOURNAL OF HEPATOLOGY

Lipocalin 2 is a Regulator Of Macrophage Polarization and NF-κB/STAT3 Pathway Activation

(2014) Hong Guo et al.   MOLECULAR ENDOCRINOLOGY

Neutrophil Gelatinase-Associated Lipocalin Increases HLA-G+/FoxP3+ T-Regulatory Cell Population in an In Vitro Model of PBMC

(2014) Gaetano La Manna et al.   PLoS One

Dendritic Cell-Secreted Lipocalin2 Induces CD8+ T-Cell Apoptosis, Contributes to T-Cell Priming and Leads to a TH1 Phenotype

(2014) Melanie Floderer et al.   PLoS One

Origin of myofibroblasts in the fibrotic liver in mice

(2014) K. Iwaisako et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis

(2013) Erawan Borkham-Kamphorst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

(2013) Joanna M. Warszawska et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipocalin 2 Bolsters Innate and Adaptive Immune Responses to Blood-Stage Malaria Infection by Reinforcing Host Iron Metabolism

(2012) Hong Zhao et al.   Cell Host & Microbe

Secreted protein lipocalin-2 promotes microglial M1 polarization

(2012) Eunha Jang et al.   FASEB JOURNAL

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

(2012) Tomonori Aoyama et al.   HEPATOLOGY

Neutrophil Gelatinase-Associated Lipocalin (NGAL) May Play a Protective Role Against Rats Ischemia/Reperfusion Renal Injury via Inhibiting Tubular Epithelial Cell Apoptosis

(2012) Shuxian An et al.   RENAL FAILURE

Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation

(2011) Erawan Borkham-Kamphorst et al.   LIVER INTERNATIONAL

CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice

(2010) Tomonori Aoyama et al.   HEPATOLOGY

CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice

(2010) Sachiko Ishikawa et al.   JOURNAL OF HEPATOLOGY

Comparison of liver regeneration after a splenectomy and splenic artery ligation in a dimethylnitrosamine-induced cirrhotic rat model

(2010) Akio Morinaga et al.   HPB

Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice

(2009) Tomonori Aoyama et al.   HEPATOLOGY

Mononuclear cells in liver fibrosis

(2009) Fabio Marra et al.   Seminars in Immunopathology

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages

(2008) Jinhui Zhang et al.   MOLECULAR ENDOCRINOLOGY

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark

Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells

(2007) Kenichi Miharada et al.   JOURNAL OF CELLULAR PHYSIOLOGY