A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructures reveals complex tumour–stroma interactions

Dynamic self-organization of microwell-aggregated cellular mixtures

(2016) Wei Song et al.   Soft Matter

Carcinoma cells induce lumen filling and EMT in epithelial cells through soluble E-cadherin-mediated activation of EGFR

(2015) P. U. Patil et al.   JOURNAL OF CELL SCIENCE

The complex seeds of metastasis

(2015) Michael M. Shen   NATURE

Beyond 3D culture models of cancer

(2015) Kandice Tanner et al.   Science Translational Medicine

Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions

(2015) Meng-Horng Lee et al.   Oncotarget

Cancer metastases: challenges and opportunities

(2015) Xiangming Guan   Acta Pharmaceutica Sinica B

Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells

(2015) Ying Qu et al.   PLoS One

Traversing the basement membrane in vivo: A diversity of strategies

(2014) Laura C. Kelley et al.   JOURNAL OF CELL BIOLOGY

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

(2014) Martina McDermott et al.   Frontiers in Oncology

Manganese Superoxide Dismutase in Cancer Prevention

(2013) Delira Robbins et al.   ANTIOXIDANTS & REDOX SIGNALING

Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells

(2013) Donghai Jiang et al.   CANCER LETTERS

An opto-thermocapillary cell micromanipulator

(2013) Wenqi Hu et al.   LAB ON A CHIP

Theory and experiment on particle trapping and manipulation via optothermally generated bubbles

(2013) Chenglong Zhao et al.   LAB ON A CHIP

Cooperative Roles of SDF-1α and EGF Gradients on Tumor Cell Migration Revealed by a Robust 3D Microfluidic Model

(2013) Beum Jun Kim et al.   PLoS One

Cell motility and drug gradients in the emergence of resistance to chemotherapy

(2013) A. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Redox Modulator, ortho Mn(III) meso-tetrakis(N-n-Hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP5+ in the Treatment of Brain Tumors

(2012) Stephen T. Keir et al.   Anti-Cancer Agents in Medicinal Chemistry

Mismatch in Mechanical and Adhesive Properties Induces Pulsating Cancer Cell Migration in Epithelial Monolayer

(2012) Meng-Horng Lee et al.   BIOPHYSICAL JOURNAL

Hydrogel microrobots actuated by optically generated vapour bubbles

(2012) Wenqi Hu et al.   LAB ON A CHIP

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

(2012) K.-V. Nguyen-Ngoc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MCF10A and MDA-MB-231 human breast basal epithelial cell co-culture in silicon micro-arrays

(2011) Mehdi Nikkhah et al.   BIOMATERIALS

Biomimetic gradient hydrogels for tissue engineering

(2010) Shilpa Sant et al.   CANADIAN JOURNAL OF CHEMICAL ENGINEERING

Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device

(2010) Tingjiao Liu et al.   LAB ON A CHIP

Biomaterials offer cancer research the third dimension

(2010) Dietmar W. Hutmacher   NATURE MATERIALS

Partitioning microfluidic channels with hydrogel to construct tunable 3-D cellular microenvironments

(2008) Amy P. Wong et al.   BIOMATERIALS

Endothelial cell polarization and chemotaxis in a microfluidic device

(2008) Amir Shamloo et al.   LAB ON A CHIP

In situ collagen assembly for integrating microfabricated three-dimensional cell-seeded matrices

(2008) Brian M. Gillette et al.   NATURE MATERIALS

Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression

(2008) Celeste M Nelson et al.   Nature Protocols