Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses

The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild

(2016) Anke Heigele et al.   Cell Host & Microbe

Tetherin Antagonism by HIV-1 Group M Nef Proteins

(2016) Juan F. Arias et al.   JOURNAL OF VIROLOGY

The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor

(2016) Birthe Trautz et al.   JOURNAL OF VIROLOGY

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

(2015) Nicholas J. Matheson et al.   Cell Host & Microbe

Acute Viral Escape Selectively Impairs Nef-Mediated Major Histocompatibility Complex Class I Downmodulation and Increases Susceptibility to Antiviral T Cells

(2015) Andrea M. Weiler et al.   JOURNAL OF VIROLOGY

Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity

(2015) Benjamin von Bredow et al.   JOURNAL OF VIROLOGY

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

Systematic Analysis of Intracellular Trafficking Motifs Located within the Cytoplasmic Domain of Simian Immunodeficiency Virus Glycoprotein gp41

(2014) Thomas S. Postler et al.   PLoS One

Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity

(2014) J. F. Arias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and full genome characterization of a new SIV lineage infecting red-tailed guenons (Cercopithecus ascanius schmidti) in Kibale National Park, Uganda

(2014) Michael Lauck et al.   Retrovirology

How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4

(2014) Xuefeng Ren et al.   eLife

Optimization of PCR for quantification of simian immunodeficiency virus genomic RNA in plasma of rhesus macaques (Macaca mulatta) using armored RNA

(2013) C.J. Monjure et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Nef-Specific CD8+ T Cell Responses Contribute to HIV-1 Immune Control

(2013) Emily Adland et al.   PLoS One

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

(2013) Jaclyn K Mann et al.   Retrovirology

Attenuation of multiple Nef functions in HIV-1 elite controllers

(2013) Philip Mwimanzi et al.   Retrovirology

Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses

(2013) Peter R. Wilker et al.   Nature Communications

Tetherin/BST-2 Antagonism by Nef Depends on a Direct Physical Interaction between Nef and Tetherin, and on Clathrin-mediated Endocytosis

(2013) Ruth Serra-Moreno et al.   PLoS Pathogens

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Escape from CD8+ T Cell Responses in Mamu-B*00801+ Macaques Differentiates Progressors from Elite Controllers

(2012) P. A. Mudd et al.   JOURNAL OF IMMUNOLOGY

Impact of HLA-B*81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

(2012) J. K. Wright et al.   JOURNAL OF VIROLOGY

Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8+ T Cells

(2012) H. N. Kloverpris et al.   JOURNAL OF VIROLOGY

Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1

(2012) J. M. Carlson et al.   JOURNAL OF VIROLOGY

Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4+ T Cell Counts in Viremic HIV-2 Infection

(2012) M. Khalid et al.   JOURNAL OF VIROLOGY

Specific CD8+ T Cell Responses Correlate with Control of Simian Immunodeficiency Virus Replication in Mauritian Cynomolgus Macaques

(2012) M. L. Budde et al.   JOURNAL OF VIROLOGY

Vaccine-induced CD8+ T cells control AIDS virus replication

(2012) Philip A. Mudd et al.   NATURE

Automated Tracking of Whiskers in Videos of Head Fixed Rodents

(2012) Nathan G. Clack et al.   PLoS Computational Biology

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Down-Modulation of CD8   Is a Fundamental Activity of Primate Lentiviral Nef Proteins

(2011) A. Heigele et al.   JOURNAL OF VIROLOGY

SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

(2011) Fengwen Zhang et al.   PLoS Pathogens

Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing

(2010) B. N. Bimber et al.   JOURNAL OF VIROLOGY

Enhanced Anti-HIV Functional Activity Associated with Gag-Specific CD8 T-Cell Responses

(2010) B. Julg et al.   JOURNAL OF VIROLOGY

Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

(2010) M. A. Brockman et al.   JOURNAL OF VIROLOGY

Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B*2705-Restricted CD8+T Cells

(2010) Rebecca P. Payne et al.   JOURNAL OF VIROLOGY

Synchronous infection of SIV and HIV in vitro for virology, immunology and vaccine-related studies

(2010) Jonah B Sacha et al.   Nature Protocols

Evolution of the HIV-1 nef gene in HLA-B*57 Positive Elite Suppressors

(2010) Maria Salgado et al.   Retrovirology

Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection

(2009) Zabrina L Brumme et al.   AIDS

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

Robust, Vaccine-Induced CD8 + T Lymphocyte Response against an Out-of-Frame Epitope

(2009) Nicholas J. Maness et al.   JOURNAL OF IMMUNOLOGY

Two MHC Class I Molecules Associated with Elite Control of Immunodeficiency Virus Replication, Mamu-B*08 and HLA-B*2705, Bind Peptides with Sequence Similarity

(2009) J. T. Loffredo et al.   JOURNAL OF IMMUNOLOGY

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients

(2008) Paul A. Goepfert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive Immunological Evaluation Reveals Surprisingly Few Differences between Elite Controller and Progressor Mamu-B*17-Positive Simian Immunodeficiency Virus-Infected Rhesus Macaques

(2008) N. J. Maness et al.   JOURNAL OF VIROLOGY

Functional Consequences of Human Immunodeficiency Virus Escape from an HLA-B*13-Restricted CD8+ T-Cell Epitope in p1 Gag Protein

(2008) J. G. Prado et al.   JOURNAL OF VIROLOGY

Protective HLA Class I Alleles That Restrict Acute-Phase CD8+ T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1

(2008) Y. E. Wang et al.   JOURNAL OF VIROLOGY

Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point

(2008) P. C. Matthews et al.   JOURNAL OF VIROLOGY