Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

(2017) Marion W. Kiguoya et al.   JOURNAL OF VIROLOGY

HIV-1 Vpu Mediates HLA-C Downregulation

(2016) Richard Apps et al.   Cell Host & Microbe

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

(2016) Macdonald Mahiti et al.   mBio

Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection

(2015) Macdonald Mahiti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion

(2015) Gursev Anmole et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

(2015) Mako Toyoda et al.   JOURNAL OF VIROLOGY

Functional Adaptation of Nef to the Immune Milieu of HIV-1 Infection In Vivo

(2014) M. J. Lewis et al.   JOURNAL OF IMMUNOLOGY

CTL-Mediated Selective Pressure Influences Dynamic Evolution and Pathogenic Functions of HIV-1 Nef

(2014) T. Ueno et al.   JOURNAL OF IMMUNOLOGY

Selection bias at the heterosexual HIV-1 transmission bottleneck

(2014) J. M. Carlson et al.   SCIENCE

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

(2013) Jaclyn K Mann et al.   Retrovirology

Attenuation of multiple Nef functions in HIV-1 elite controllers

(2013) Philip Mwimanzi et al.   Retrovirology

Dynamic range of Nef functions in chronic HIV-1 infection

(2013) Philip Mwimanzi et al.   VIROLOGY

Implications of HIV diversity for the HIV-1 pandemic

(2012) Joris Hemelaar   JOURNAL OF INFECTION

A Noncanonical mu-1A-Binding Motif in the N Terminus of HIV-1 Nef Determines Its Ability To Downregulate Major Histocompatibility Complex Class I in T Lymphocytes

(2012) S. Iijima et al.   JOURNAL OF VIROLOGY

Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef

(2012) Xiaofei Jia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation

(2012) U. S. Rajapaksa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy

(2011) Peter W. Hunt et al.   AIDS

Down-Modulation of CD8   Is a Fundamental Activity of Primate Lentiviral Nef Proteins

(2011) A. Heigele et al.   JOURNAL OF VIROLOGY

Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages

(2011) Philip Mwimanzi et al.   Retrovirology

Additive Contribution of HLA Class I Alleles in the Immune Control of HIV-1 Infection

(2010) A. Leslie et al.   JOURNAL OF VIROLOGY

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins

(2009) Zabrina L. Brumme et al.   PLoS One

Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241???249 epitope

(2008) Tetsuo Tsukamoto et al.   AIDS

Selective Downregulation of Rhesus Macaque and Sooty Mangabey Major Histocompatibility Complex Class I Molecules by Nef Alleles of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2

(2008) M. Q. DeGottardi et al.   JOURNAL OF VIROLOGY

Selective downmodulation of HLA-A and -B by Nef alleles from different groups of primate lentiviruses

(2007) Anke Specht et al.   VIROLOGY