Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application
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Title
Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application
Authors
Keywords
Cancer immunotherapy, Toll-like receptor 9, B-cell malignancies, CpG oligodeoxynucleotides
Journal
Journal of Translational Medicine
Volume 15, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-02-27
DOI
10.1186/s12967-017-1152-5
References
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Note: Only part of the references are listed.- CpG-1826 immunotherapy potentiates chemotherapeutic and anti-tumor immune responses to metronomic cyclophosphamide in a preclinical glioma model
- (2016) Marie Jordan et al. CANCER LETTERS
- Distinct TLR-mediated cytokine production and immunoglobulin secretion in human newborn naïve B cells
- (2016) Matthew A Pettengill et al. Innate Immunity
- Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis
- (2016) Maren Feist et al. INTERNATIONAL JOURNAL OF CANCER
- CD19 controls Toll-like receptor 9 responses in human B cells
- (2016) Henner Morbach et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies
- (2016) Stavroula Ntoufa et al. SEMINARS IN CANCER BIOLOGY
- Targeted Therapy for Chronic Lymphocytic Leukemia: Current Status and Future Directions
- (2015) Jon E. Arnason et al. DRUGS
- Regulatory B cells mediate tolerance to apoptotic self in health: implications for disease: Fig. 1.
- (2015) Mohini Gray et al. INTERNATIONAL IMMUNOLOGY
- TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells
- (2015) Patricia K. A. Mongini et al. JOURNAL OF IMMUNOLOGY
- CD19-Chimeric Antigen Receptor T Cells for Treatment of Chronic Lymphocytic Leukaemia and Acute Lymphoblastic Leukaemia
- (2015) C. L. Lorentzen et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Lymphoma Immunotherapy: Current Status
- (2015) Roberta Zappasodi et al. Frontiers in Immunology
- Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome
- (2014) A. Martinez-Trillos et al. BLOOD
- TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response
- (2014) Thomas Guerrier et al. JOURNAL OF AUTOIMMUNITY
- Consequences of the recurrentMYD88L265Psomatic mutation for B cell tolerance
- (2014) James Q. Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Heterogeneous Functional Effects of Concomitant B Cell Receptor and TLR Stimulation in Chronic Lymphocytic Leukemia with Mutated versus Unmutated Ig Genes
- (2014) M. Chatzouli et al. JOURNAL OF IMMUNOLOGY
- A novel TLR-9 agonist C792 inhibits plasmacytoid dendritic cell-induced myeloma cell growth and enhance cytotoxicity of bortezomib
- (2014) A Ray et al. LEUKEMIA
- Mitogen-Induced B-Cell Proliferation Activates Chk2-Dependent G1/S Cell Cycle Arrest
- (2014) Pavel A. Nikitin et al. PLoS One
- TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo
- (2013) Q. Zhang et al. BLOOD
- Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity
- (2013) D. M. S. Hossain et al. BLOOD
- Toll-like receptor agonists induce apoptosis in mouse B-cell lymphoma cells by altering NF-κB activation
- (2013) Nandini Arunkumar et al. Cellular & Molecular Immunology
- Lymphoma B-cell responsiveness to CpG-DNA depends on the tumor microenvironment
- (2013) Rym Ben Abdelwahed et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Bruton’s Tyrosine Kinase Mediates the Synergistic Signalling between TLR9 and the B Cell Receptor by Regulating Calcium and Calmodulin
- (2013) Elaine F. Kenny et al. PLoS One
- Plasmacytoid dendritic cells and immunotherapy in multiple sclerosis
- (2012) Felipe von Glehn et al. Immunotherapy
- TLR9 drives the development of transitional B cells towards the marginal zone pathway and promotes autoimmunity
- (2012) Thomas Guerrier et al. JOURNAL OF AUTOIMMUNITY
- Combination of Cyclophosphamide, Rituximab, and Intratumoral CpG Oligodeoxynucleotide Successfully Eradicates Established B cell Lymphoma
- (2012) David J. Betting et al. JOURNAL OF IMMUNOTHERAPY
- TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism
- (2012) J Noack et al. Cell Death & Disease
- Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients
- (2011) E. Arvaniti et al. HAEMATOLOGICA
- Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia
- (2011) Clive S. Zent et al. LEUKEMIA & LYMPHOMA
- Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses
- (2010) Roberto Lande et al. Annals of the New York Academy of Sciences
- Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells
- (2010) X. Liang et al. BLOOD
- Targeting the TLR9–MyD88 pathway in the regulation of adaptive immune responses
- (2010) Xiaopei Huang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Innate immunity and cancer therapy
- (2010) Kouji Maruyama et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- TLR1/2, TLR7, and TLR9 Signals Directly Activate Human Peripheral Blood Naive and Memory B Cell Subsets to Produce Cytokines, Chemokines, and Hematopoietic Growth Factors
- (2010) Sudhanshu Agrawal et al. JOURNAL OF CLINICAL IMMUNOLOGY
- In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study
- (2010) Joshua D. Brody et al. JOURNAL OF CLINICAL ONCOLOGY
- Oncogenically active MYD88 mutations in human lymphoma
- (2010) Vu N. Ngo et al. NATURE
- Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis
- (2010) Julie A Di Paolo et al. Nature Chemical Biology
- CpG ODN Enhances the Efficacy of Rituximab in Non-Hodgkin Lymphoma
- (2009) Virginie Buhé et al. Annals of the New York Academy of Sciences
- BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation
- (2009) J. Eckl-Dorna et al. BLOOD
- Randomized phase 2/3 trial of CpG oligodeoxynucleotide PF-3512676 alone or with dacarbazine for patients with unresectable stage III and IV melanoma
- (2009) Jeffrey S. Weber et al. CANCER
- Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target
- (2009) Dharminder Chauhan et al. CANCER CELL
- Intratumoral But Not Systemic Delivery of CpG Oligodeoxynucleotide Augments the Efficacy of Anti-CD20 Monoclonal Antibody Therapy Against B Cell Lymphoma
- (2009) David J. Betting et al. JOURNAL OF IMMUNOTHERAPY
- TLR9 Signaling Promotes Tumor Progression of Human Lung Cancer Cell In Vivo
- (2009) Tao Ren et al. PATHOLOGY & ONCOLOGY RESEARCH
- TLR9 as a key receptor for the recognition of DNA☆
- (2008) Y KUMAGAI et al. ADVANCED DRUG DELIVERY REVIEWS
- Toll-like receptors: lessons to learn from normal and malignant human B cells
- (2008) D. Chiron et al. BLOOD
- Proteasome inhibition suppresses essential immune functions of human CD4+T cells
- (2008) Carsten Berges et al. IMMUNOLOGY
- PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
- (2008) Cristiana Guiducci et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours
- (2008) H Conroy et al. ONCOGENE
- Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis
- (2008) J. B. Swann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of TLR activation in inflammation
- (2007) I Sabroe et al. JOURNAL OF PATHOLOGY
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