The spleen in liver cirrhosis: revisiting an old enemy with novel targets
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The spleen in liver cirrhosis: revisiting an old enemy with novel targets
Authors
Keywords
Splenomegaly, Hypersplenism, Liver cirrhosis, Hepatic fibrogenesis, Hepatic immune microenvironment, Liver regeneration, Nanomedicine
Journal
Journal of Translational Medicine
Volume 15, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-05-23
DOI
10.1186/s12967-017-1214-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- It takes nerve to fight back: The significance of neural innervation of the bone marrow and spleen for immune function
- (2017) Won-Cheol Jung et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Neuroimmunity: Physiology and Pathology
- (2016) Sébastien Talbot et al. Annual Review of Immunology
- Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury
- (2016) Elena Arriazu et al. GUT
- Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis
- (2016) Wonhyo Seo et al. HEPATOLOGY
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate
- (2016) Hiroyuki Nojima et al. JOURNAL OF HEPATOLOGY
- Liver regeneration — mechanisms and models to clinical application
- (2016) Stuart J. Forbes et al. Nature Reviews Gastroenterology & Hepatology
- Rapamycin Attenuates Splenomegaly in both Intrahepatic and Prehepatic Portal Hypertensive Rats by Blocking mTOR Signaling Pathway
- (2016) Yunyang Chen et al. PLoS One
- mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function
- (2016) Nyamdelger Sukhbaatar et al. TRENDS IN IMMUNOLOGY
- FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly
- (2016) Audrey Romano et al. PLoS Neglected Tropical Diseases
- Pathobiology of liver fibrosis: a translational success story
- (2015) Youngmin A Lee et al. GUT
- Kupffer cell-monocyte communication is essential for initiating murine liver progenitor cell-mediated liver regeneration
- (2015) Caryn L. Elsegood et al. HEPATOLOGY
- Liver regeneration after splenectomy in patients with liver cirrhosis
- (2015) Shinichiro Yamada et al. HEPATOLOGY RESEARCH
- Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice
- (2015) Kazutaka Tanabe et al. JOURNAL OF GASTROENTEROLOGY
- Splenectomy attenuates murine liver fibrosis with hypersplenism stimulating hepatic accumulation of Ly-6Clo macrophages
- (2015) Akito Yada et al. JOURNAL OF HEPATOLOGY
- Role of the spleen in liver regeneration in relation to transforming growth factor-β1 and hepatocyte growth factor
- (2015) Sang Chul Lee et al. JOURNAL OF SURGICAL RESEARCH
- Spleen Size in Cirrhosis of Different Etiologies
- (2015) Amir Kashani et al. JOURNAL OF ULTRASOUND IN MEDICINE
- Splenectomy enhances the therapeutic effect of adipose tissue-derived mesenchymal stem cell infusion on cirrhosis rats
- (2015) Wei-Ping Tang et al. LIVER INTERNATIONAL
- Targeted chemotherapy of visceral leishmaniasis by lactoferrin-appended amphotericin B-loaded nanoreservoir: in vitro and in vivo studies.
- (2015) Shalini Asthana et al. Nanomedicine
- Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific
- (2015) K.-H. Chen et al. Nanoscale
- Principles of nanoparticle design for overcoming biological barriers to drug delivery
- (2015) Elvin Blanco et al. NATURE BIOTECHNOLOGY
- Pathophysiology of Portal Hypertension
- (2014) Yasuko Iwakiri Clinics in Liver Disease
- Efficacy and safety of splenectomy in telaprevir-based triple therapy for chronic hepatitis C patients with thrombocytopenia and advanced fibrosis
- (2014) Eiichi Ogawa et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Liver cirrhosis
- (2014) Emmanuel A Tsochatzis et al. LANCET
- Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages
- (2014) Fatemeh Momen-Heravi et al. Nanomedicine-Nanotechnology Biology and Medicine
- Spleen supports a pool of innate-like B cells in white adipose tissue that protects against obesity-associated insulin resistance
- (2014) L. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation
- (2013) Kaori Kuramitsu et al. AMERICAN JOURNAL OF PATHOLOGY
- CD169 mediates the capture of exosomes in spleen and lymph node
- (2013) S. C. Saunderson et al. BLOOD
- Splenectomy prior to antiviral therapy in patients with hepatitis C virus related decompensated cirrhosis
- (2013) Fanpu Ji et al. Brazilian Journal of Infectious Diseases
- Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion
- (2013) Michael J. Williams et al. GASTROENTEROLOGY
- Spleen stiffness: Toward a noninvasive portal sphygmomanometer?
- (2013) Juan G. Abraldes et al. HEPATOLOGY
- Cytokine expression in spleen affects progression of liver cirrhosis through liver-spleen cross-talk
- (2013) Michihito Asanoma et al. HEPATOLOGY RESEARCH
- Influence of splenectomy in patients with liver cirrhosis and hypersplenism
- (2013) Yoriko Nomura et al. HEPATOLOGY RESEARCH
- The Spleen in Local and Systemic Regulation of Immunity
- (2013) Vincenzo Bronte et al. IMMUNITY
- Decoding cell death signals in liver inflammation
- (2013) Catherine Brenner et al. JOURNAL OF HEPATOLOGY
- Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases
- (2013) Anatoliy I. Masyuk et al. JOURNAL OF HEPATOLOGY
- HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6Chighinflammatory monocytes in murine sepsis survivors
- (2013) S. I. Valdés-Ferrer et al. JOURNAL OF INTERNAL MEDICINE
- Liver-spleen axis: Intersection between immunity, infections and metabolism
- (2013) Giovanni Tarantino WORLD JOURNAL OF GASTROENTEROLOGY
- Regulation of Immune Responses by mTOR
- (2012) Jonathan D. Powell et al. Annual Review of Immunology
- Measurement of Spleen Stiffness to Evaluate Portal Hypertension and the Presence of Esophageal Varices in Patients With HCV-Related Cirrhosis
- (2012) Antonio Colecchia et al. GASTROENTEROLOGY
- NF-κB p65 and c-Rel subunits promote phagocytosis and cytokine secretion by splenic macrophages in cirrhotic patients with hypersplenism
- (2012) Song Ren et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis:in vitroandin vivostudies
- (2012) Sofia A Costa Lima et al. Nanomedicine
- Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
- (2012) Luke Boulter et al. NATURE MEDICINE
- Pathogenesis of Liver Fibrosis
- (2011) Virginia Hernandez-Gea et al. Annual Review of Pathology-Mechanisms of Disease
- Exosome nanotechnology: An emerging paradigm shift in drug delivery
- (2011) Samira Lakhal et al. BIOESSAYS
- Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen
- (2011) T. L. McGaha et al. BLOOD
- miR-615-3p promotes the phagocytic capacity of splenic macrophages by targeting ligand-dependent nuclear receptor corepressor in cirrhosis-related portal hypertension
- (2011) An Jiang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients
- (2011) Takuya Iwamoto et al. JOURNAL OF GASTROENTEROLOGY
- Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform
- (2011) C.-M. J. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PI3K/AKT/mTOR Pathway in Angiogenesis
- (2011) Jayashree Karar et al. Frontiers in Molecular Neuroscience
- Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution
- (2010) G. Kovtunovych et al. BLOOD
- Relevance of the mTOR signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension
- (2010) Marc Mejias et al. JOURNAL OF HEPATOLOGY
- Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis
- (2010) Eleonora Patsenker et al. JOURNAL OF HEPATOLOGY
- Co-ordinated Gene Expression in the Liver and Spleen during Schistosoma japonicum Infection Regulates Cell Migration
- (2010) Melissa L. Burke et al. PLoS Neglected Tropical Diseases
- Dysfunction of Splenic Macrophages in Cirrhotic Patients With Hypersplenism and HBV Infection
- (2009) Aimin Li et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
- (2009) F. K. Swirski et al. SCIENCE
- Spleen Enlargement on Follow-Up Evaluation: A Noninvasive Predictor of Complications of Portal Hypertension in Cirrhosis
- (2008) Annalisa Berzigotti et al. Clinical Gastroenterology and Hepatology
- MicroRNAome of Splenic Macrophages in Hypersplenism due to Portal Hypertension in Hepatitis B Virus-Related Cirrhosis
- (2008) Zongfang Li et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
- (2008) Masako Kohyama et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search