MicroRNAs and Noncoding RNAs in Hepatic Lipid and Lipoprotein Metabolism: Potential Therapeutic Targets of Metabolic Disorders

Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1

(2015) Yun-cheng Lv et al.   ATHEROSCLEROSIS

Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9-Mediated RXRA Signaling Pathway

(2015) M. Cui et al.   CANCER RESEARCH

A Liver-Enriched Long Non-Coding RNA, lncLSTR, Regulates Systemic Lipid Metabolism in Mice

(2015) Ping Li et al.   Cell Metabolism

The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells

(2015) Joseph Mazar et al.   Oncotarget

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis

(2014) Qiaozhu Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA regulation of mitochondrial and ER stress signaling pathways: implications for lipoprotein metabolism in metabolic syndrome

(2014) Patricia Christian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages

(2014) Min Zhang et al.   ATHEROSCLEROSIS

miR-613 regulates cholesterol efflux by targeting LXRα and ABCA1 in PPARγ activated THP-1 macrophages

(2014) Ranzun Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4

(2014) Ming Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-205 modulates abnormal lipid metabolism of hepatoma cells via targeting acyl-CoA synthetase long-chain family member 1 (ACSL1) mRNA

(2014) Ming Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

(2014) L. Goedeke et al.   EMBO Molecular Medicine

Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

(2014) Raymond Ng et al.   HEPATOLOGY

Aberrant miR199a-5p/caveolin1/PPARα axis in hepatic steatosis

(2014) Bo Li et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

A Novel RNA Motif Mediates the Strict Nuclear Localization of a Long Noncoding RNA

(2014) B. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-223 coordinates cholesterol homeostasis

(2014) Kasey C. Vickers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes

(2014) Sebastiaan van Heesch et al.   GENOME BIOLOGY

Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145

(2013) Martin H. Kang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Hypoxia-Inducible MicroRNA Cluster miR-199a∼214 Targets Myocardial PPARδ and Impairs Mitochondrial Fatty Acid Oxidation

(2013) Hamid el Azzouzi et al.   Cell Metabolism

Estimating Deaths From Cardiovascular Disease: A Review of Global Methodologies of Mortality Measurement

(2013) Neha Jadeja Pagidipati et al.   CIRCULATION

Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144

(2013) Cristina M. Ramírez et al.   CIRCULATION RESEARCH

MicroRNAs 185, 96, and 223 Repress Selective High-Density Lipoprotein Cholesterol Uptake through Posttranscriptional Inhibition

(2013) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

MiR-155 Has a Protective Role in the Development of Non-Alcoholic Hepatosteatosis in Mice

(2013) Ashley M. Miller et al.   PLoS One

Early steps in reverse cholesterol transport

(2013) Shobha Ghosh   Current Opinion in Endocrinology Diabetes and Obesity

miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis

(2013) Y K Adlakha et al.   Cell Death & Disease

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice

(2013) Takahiro Horie et al.   Nature Communications

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7

(2012) Dongsheng Sun et al.   FEBS LETTERS

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

(2012) Shu-hao Hsu et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease

(2012) Wei Gao et al.   Lipids in Health and Disease

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts

(2012) Marco Magistri et al.   TRENDS IN GENETICS

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

(2012) Erin E. Mulvihill et al.   PPAR Research

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

(2011) Cristina M. Ramirez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adipose Tissue ATP Binding Cassette Transporter A1 Contributes to High-Density Lipoprotein Biogenesis In Vivo

(2011) Soonkyu Chung et al.   CIRCULATION

miR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression

(2011) Jaekwang Kim et al.   EXPERIMENTAL NEUROLOGY

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

(2011) Katey J. Rayner et al.   JOURNAL OF CLINICAL INVESTIGATION

Alzheimer-specific variants in the 3'UTR of Amyloid precursor protein affect microRNA function

(2011) Charlotte Delay et al.   Molecular Neurodegeneration

PCSK9 LNA Antisense Oligonucleotides Induce Sustained Reduction of LDL Cholesterol in Nonhuman Primates

(2011) Marie W Lindholm et al.   MOLECULAR THERAPY

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

PPARα Is Regulated by miR-21 and miR-27b in Human Liver

(2011) Katsuhiko Kida et al.   PHARMACEUTICAL RESEARCH

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

(2011) A. Davalos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

(2011) O. Rackham et al.   RNA

Apolipoprotein B: not just a biomarker but a causal factor in hepatic endoplasmic reticulum stress and insulin resistance

(2010) Qiaozhu Su et al.   Clinical Lipidology

Expression of miR-33 from anSREBP2Intron Inhibits Cholesterol Export and Fatty Acid Oxidation

(2010) Isabelle Gerin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

(2010) F. Moretti et al.   RNA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance

(2009) Qiaozhu Su et al.   HEPATOLOGY

The Non-coding RNAgadd7Is a Regulator of Lipid-induced Oxidative and Endoplasmic Reticulum Stress

(2009) Rita T. Brookheart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100

(2008) Rosie Z. Yu et al.   BIOCHEMICAL PHARMACOLOGY