Sparse Simultaneous Signal Detection for Identifying Genetically Controlled Disease Genes

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Hypothesis testing for high-dimensional sparse binary regression

(2015) Rajarshi Mukherjee et al.   ANNALS OF STATISTICS

Polycomb Regulates Mesoderm Cell Fate-Specification in Embryonic Stem Cells through Activation and Repression Mechanisms

(2015) Lluis Morey et al.   Cell Stem Cell

MicroRNA-101 Inhibits Rat Cardiac Hypertrophy by Targeting Rab1a

(2015) Longxiao Wei et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

A gene-based association method for mapping traits using reference transcriptome data

(2015) Eric R Gamazon et al.   NATURE GENETICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

ATP-binding cassette transporter Abcg2 lineage contributes to the cardiac vasculature after oxidative stress

(2014) Travis J. Maher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

More powerful genetic association testing via a new statistical framework for integrative genomics

(2014) Sihai D. Zhao et al.   BIOMETRICS

Integrative modeling of multiple genomic data from different types of genetic association studies

(2014) Yen-Tsung Huang   BIOSTATISTICS

CENP-A is essential for cardiac progenitor cell proliferation

(2014) Michael McGregor et al.   CELL CYCLE

Optimal Detection of Sparse Mixtures Against a Given Null Distribution

(2014) Tony T. Cai et al.   IEEE TRANSACTIONS ON INFORMATION THEORY

GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation

(2014) Dongjun Chung et al.   PLoS Genetics

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS

(2013) Xin He et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GWAS on your notebook: fast semi-parallel linear and logistic regression for genome-wide association studies

(2013) Karolina Sikorska et al.   BMC BIOINFORMATICS

Epidemiology of Heart Failure

(2013) Véronique L. Roger   CIRCULATION RESEARCH

Two-Sample Covariance Matrix Testing and Support Recovery in High-Dimensional and Sparse Settings

(2013) Tony Cai et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Integrative genomics in cardiovascular medicine

(2012) J. S. Ware et al.   CARDIOVASCULAR RESEARCH

Multiple Biomarkers for Risk Prediction in Chronic Heart Failure

(2012) Bonnie Ky et al.   Circulation-Heart Failure

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Global testing under sparse alternatives: ANOVA, multiple comparisons and the higher criticism

(2011) Ery Arias-Castro et al.   ANNALS OF STATISTICS

The ATP-Binding Cassette Transporter ABCG2 Protects Against Pressure Overload–Induced Cardiac Hypertrophy and Heart Failure by Promoting Angiogenesis and Antioxidant Response

(2011) Yasutomi Higashikuni et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sample size and power analysis for sparse signal recovery in genome-wide association studies

(2011) J. Xie et al.   BIOMETRIKA

Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets

(2011) Q. Xiong et al.   GENOME RESEARCH

Optimal detection of heterogeneous and heteroscedastic mixtures

(2011) T. Tony Cai et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Robustness and accuracy of methods for high dimensional data analysis based on Student's t-statistic

(2011) Aurore Delaigle et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Heart failure: advances through genomics

(2011) Esther E. Creemers et al.   NATURE REVIEWS GENETICS

Loss-of-function DNA sequence variant in the CLCNKA chloride channel implicates the cardio-renal axis in interindividual heart failure risk variation

(2011) T. P. Cappola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innovated higher criticism for detecting sparse signals in correlated noise

(2010) Peter Hall et al.   ANNALS OF STATISTICS

High-Sensitivity ST2 for Prediction of Adverse Outcomes in Chronic Heart Failure

(2010) Bonnie Ky et al.   Circulation-Heart Failure

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

(2010) Arsen Petrovic et al.   JOURNAL OF CELL BIOLOGY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Variants ofDENND1BAssociated with Asthma in Children

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Neuregulin-1β Is Associated With Disease Severity and Adverse Outcomes in Chronic Heart Failure

(2009) Bonnie Ky et al.   CIRCULATION

A new measure of the effective number of tests, a practical tool for comparing families of non-independent significance tests

(2009) Nicholas W. Galwey   GENETIC EPIDEMIOLOGY

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Architecture of Transcript-Level Variation in Humans

(2008) Shiwei Duan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Properties of higher criticism under strong dependence

(2008) Peter Hall et al.   ANNALS OF STATISTICS

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Tackling heart failure in the twenty-first century

(2008) James O. Mudd et al.   NATURE

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE