Raman optical activity of human α -synuclein in intrinsically disordered, micelle-bound α -helical, molten globule and oligomeric β -sheet state

Structural disorder of monomeric α-synuclein persists in mammalian cells

(2016) Francois-Xavier Theillet et al.   NATURE

α-synuclein folds: the cards are on the table

(2016) Wouter Peelaerts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ramachandran mapping of peptide conformation using a large database of computed Raman and Raman optical activity spectra

(2016) Carl Mensch et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

α-synuclein folds: the cards are on the table

(2016) Wouter Peelaerts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

First-Principles Predictions of Vibrational Raman Optical Activity of Globular Proteins

(2015) Jiří Kessler et al.   Journal of Physical Chemistry Letters

Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity

(2015) Daniel Ysselstein et al.   NEUROBIOLOGY OF DISEASE

Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation

(2015) Dhiman Ghosh et al.   Scientific Reports

A novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology

(2014) Petra Pasanen et al.   NEUROBIOLOGY OF AGING

Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease

(2014) Gergely Tóth et al.   PLoS One

G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome

(2013) Suzanne Lesage et al.   ANNALS OF NEUROLOGY

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

Characteristic Raman Optical Activity Signatures of Protein β-Sheets

(2013) Thomas Weymuth et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Raman spectroscopy of proteins: a review

(2013) A. Rygula et al.   JOURNAL OF RAMAN SPECTROSCOPY

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

(2013) Silke Appel-Cresswell et al.   MOVEMENT DISORDERS

Predictive Atomic Resolution Descriptions of Intrinsically Disordered hTau40 and α-Synuclein in Solution from NMR and Small Angle Scattering

(2013) Martin Schwalbe et al.   STRUCTURE

100 years of Lewy pathology

(2012) Michel Goedert et al.   Nature Reviews Neurology

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Raman optical activity study on insulin amyloid- and prefibril intermediate

(2011) Shigeki Yamamoto et al.   CHIRALITY

SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway

(2010) Lise Giehm et al.   JOURNAL OF MOLECULAR BIOLOGY

A Combinatorial NMR and EPR Approach for Evaluating the Structural Ensemble of Partially Folded Proteins

(2010) Jampani Nageswara Rao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formation and structure of the potassium complex of valinomycin in solution studied by Raman optical activity spectroscopy

(2010) Shigeki Yamamoto et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation

(2010) V. L. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of the Free Energy Landscape of α-Synuclein Using Spin Label Nuclear Magnetic Resonance Measurements

(2009) Jane R. Allison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Slow formation of aggregation-resistant β-sheet folding intermediates

(2009) Mirco Junker et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Calculated Raman Optical Activity Signatures of Tryptophan Side Chains

(2008) Christoph R. Jacob et al.   CHEMPHYSCHEM