A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding

Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies

(2017) X Xiao et al.   MOLECULAR PSYCHIATRY

An update on the physiological and therapeutic relevance of GPCR oligomers

(2017) Batoul Farran   PHARMACOLOGICAL RESEARCH

Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci

(2017) Atsushi Takata et al.   Nature Communications

Advances in the genetics of schizophrenia: toward a network and pathway view for drug discovery

(2016) David A. Collier et al.   Annals of the New York Academy of Sciences

Genome-wide changes in lncRNA, splicing and regional gene expression patterns in autism

(2016) Neelroop N. Parikshak et al.   NATURE

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

(2016) Ming Li et al.   NATURE MEDICINE

Gene expression elucidates functional impact of polygenic risk for schizophrenia

(2016) Menachem Fromer et al.   NATURE NEUROSCIENCE

Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study

(2016) Aintzane García-Bea et al.   SCHIZOPHRENIA RESEARCH

RNA splicing is a primary link between genetic variation and disease

(2016) Yang I. Li et al.   SCIENCE

Exploratory Analysis for a Targeted Patient Population Responsive to the Metabotropic Glutamate 2/3 Receptor Agonist Pomaglumetad Methionil in Schizophrenia

(2015) Bruce J. Kinon et al.   BIOLOGICAL PSYCHIATRY

Revealing G-protein-coupled receptor oligomerization at the single-molecule level through a nanoscopic lens: methods, dynamics and biological function

(2015) Marco Scarselli et al.   FEBS Journal

Conformational dynamics of a class C G-protein-coupled receptor

(2015) Reza Vafabakhsh et al.   NATURE

Recent genetic findings in schizophrenia and their therapeutic relevance

(2014) Paul J Harrison   JOURNAL OF PSYCHOPHARMACOLOGY

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse

(2014) S H Kim et al.   MOLECULAR PSYCHIATRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Translating Human Genetics into Novel Treatment Targets for Schizophrenia

(2014) Christian R. Schubert et al.   NEURON

Expression ofZNF804Ain Human Brain and Alterations in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

(2014) Ran Tao et al.   JAMA Psychiatry

Genetic Association, Mutation Screening, and Functional Analysis of a Kozak Sequence Variant in the Metabotropic Glutamate Receptor 3 Gene in Bipolar Disorder

(2013) Radhika Kandaswamy et al.   JAMA Psychiatry

Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins

(2011) Ana C Magalhaes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Interdomain movements in metabotropic glutamate receptor activation

(2011) S. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Genetic Neuropathology of Schizophrenia: New Approaches to an Old Question and New Uses for Postmortem Human Brains

(2010) Joel E. Kleinman et al.   BIOLOGICAL PSYCHIATRY

G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function

(2009) Graeme Milligan   BRITISH JOURNAL OF PHARMACOLOGY

Group II metabotropic glutamate receptors and schizophrenia

(2009) José L. Moreno et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Review: The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia

(2008) PJ Harrison et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Identification of a serotonin/glutamate receptor complex implicated in psychosis

(2008) Javier González-Maeso et al.   NATURE

Expression of a GRM3 Splice Variant is Increased in the Dorsolateral Prefrontal Cortex of Individuals Carrying a Schizophrenia Risk SNP

(2008) Leah J Sartorius et al.   NEUROPSYCHOPHARMACOLOGY

Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors

(2008) Richard Einstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA