Article
Agriculture, Multidisciplinary
Xue Luo, Mo Li, Henan Zhang, Danli Yan, Shuaiqi Ji, Rina Wu, Yongfu Chen
Summary: Proteomics and bioinformatics analysis of three strains of Lactobacillus plantarum under salt stress revealed differential expression of proteins related to protein biosynthesis, nucleotide metabolism, and sugar metabolism. Specific differentially expressed proteins were found between the strains in response to high salt conditions.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Biotechnology & Applied Microbiology
Jiafeng Xia, Shiman Jiang, Longxian Lv, Wenrui Wu, Qiangqiang Wang, Qiaomai Xu, Jianzhong Ye, Daiqiong Fang, Yating Li, Jingjing Wu, Xiaoyuan Bian, Liya Yang, Huiyong Jiang, Kaicen Wang, Ren Yan, Lanjuan Li
Summary: Lactobacillus salivarius LI01 can directly impact the host by modulating immunity and metabolism, including restoring levels of serum biomarkers, activating Th0 cell differentiation, stimulating immune response and metabolic processes, among other effects.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Agricultural Engineering
Lamei Zheng, Wuyun Wu, Qingyu Chen, Genfa Zhang, Fei Gao, Yijun Zhou
Summary: This study investigated the metabolic pathways and molecular mechanisms associated with heat stress response in jojoba leaves using a combination of physiological and multi-omics techniques. The results showed that protein folding and sorting, photosynthesis, signal pathways, ROS scavenging, energy metabolism, and carbohydrate metabolism were closely related to the heat stress response of jojoba. Metabolomics analysis identified significant changes in the content of certain metabolites under heat stress. Multi-omics analysis revealed the important roles of soluble sugars and amino acids in maintaining osmotic balance and alleviating heat stress-induced damage.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Review
Plant Sciences
Kasinathan Rakkammal, Arumugam Priya, Subramani Pandian, Theivanayagam Maharajan, Periyasamy Rathinapriya, Lakkakula Satish, Stanislaus Antony Ceasar, Soo-In Sohn, Manikandan Ramesh
Summary: Cereals have developed various tolerance mechanisms to cope with abiotic stress. The omics field, including genomics, transcriptomics, and proteomics, has made significant progress in understanding these mechanisms. Integrated omics and bioinformatics approaches are crucial for studying genome-wide stress-regulation mechanisms.
Article
Biochemistry & Molecular Biology
Daniel Zamith-Miranda, Rafaela F. Amatuzzi, Isadora F. Munhoz da Rocha, Sharon T. Martins, Aline C. R. Lucena, Alexandre Z. Vieira, Gabriel Trentin, Fausto Almeida, Marcio L. Rodrigues, Ernesto S. Nakayasu, Joshua D. Nosanchuk, Lysangela R. Alves
Summary: Candida auris has emerged as a serious global threat due to its high resistance to conventional antifungal medications. This study treated two strains of C. auris with caspofungin and found that it caused morphological alterations, changes in cell wall composition, and upregulation of genes related to cell wall synthesis. These results provide valuable insights into the biology of C. auris and the antifungal activity of caspofungin, identifying potential cellular targets for the development of novel antifungals.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Article
Microbiology
Qiqi Pan, Xudan Shen, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai
Summary: The study explored common functional genes for bile salt resistance in 90 Lactobacillus salivarius strains, identifying genes related to peptidoglycan synthesis, phosphotransferase system, and stress response as key factors. A significant association was found between GATase1-encoding gene and bile salt tolerance. Additionally, global regulatory genes for bile salt tolerance were identified, offering a potential method for rapid screening of bile salt-tolerant L. salivarius strains based on PCR amplification of functional genes.
Article
Chemistry, Applied
Anyi Wang, Jun Lin, Qixin Zhong
Summary: This study introduces novel modified rice protein (MRP)-ammonium shellac (NH4SL) enteric composite coatings to protect probiotics during storage, thermal treatments, and simulated gastrointestinal digestions. The MRPpH13-NH4SL suspension showed better stability than other suspensions due to the improved solubility and stability of MRP at a higher pH. Overall, the composite coatings significantly enhanced the viability of probiotics in various conditions, making them a promising option for probiotic-containing products.
FOOD HYDROCOLLOIDS
(2021)
Article
Plant Sciences
Ge Bai, Dun-Huang Fang, Da-Hai Yang, Zhi-Jun Tong, Xue-Jun Chen, Ming-Liang Fei, Jiu-Ling Gong, He Xie, Bing-Guang Xiao
Summary: This study investigates the function of the Php gene in black shank disease resistance and its relationship with the NtPR-1B gene in tobacco. The results suggest that both genes may play similar roles in protecting tobacco from black shank disease.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Microbiology
Mohd Affan Baig, Mark S. Turner, Shao-Quan Liu, Anas A. Al-Nabulsi, Nagendra P. Shah, Mutamed M. Ayyash
Summary: This study evaluated the differential proteomic responses of the potential novel probiotic Pediococcus pentosaceus M41 under various stress conditions, identifying stress response proteins that may provide tolerance against these stresses and could be used as probiotic markers for evaluating stress tolerance. The proteomic analysis revealed that certain proteins were commonly upregulated or downregulated under different stress conditions, indicating their importance in the stress response of P. pentosaceus M41.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Damayanti Chakravarty, Gyan Sahukhal, Mark Arick II, Morgan L. Davis, Janet R. Donaldson
Summary: This study analyzed the differences in transcript levels produced by Listeria monocytogenes under conditions mimicking the gastrointestinal tract, revealing that anaerobic environments have an impact on gene transcription, particularly under acidic conditions. These findings provide comprehensive information on how L. monocytogenes responds to the gastrointestinal tract.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Priyadarshani Choudhary, Heinz-Bernhard Kraatz, Celine M. Levesque, Siew-Ging Gong
Summary: This study aimed to develop a delivery system for LAB813, a newly identified S. salivarius strain. Polysaccharides such as alginate and chitosan were tested for encapsulating LAB813, and chitosan-coated alginate microcapsules showed superior antibacterial properties. These microcapsules retained their antibacterial activity for up to 28 days, highlighting their potential for improving oral health.
Article
Food Science & Technology
Anyi Wang, Jun Lin, Qixin Zhong
Summary: Probiotics have shown potential as alternatives to antibiotics in poultry production. The study demonstrated that supplementing probiotics on broiler feed pellets can improve bacterial viability under optimized conditions, offering a significant approach for probiotic supplementation in animals.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Slawomir Borek, Szymon Stefaniak, Katarzyna Nuc, Lukasz Wojtyla, Ewelina Ratajczak, Ewa Sitkiewicz, Agata Malinowska, Bianka Swiderska, Karolina Wleklik, Malgorzata Pietrowska-Borek
Summary: During seed germination, under nutrient deficiency or starvation conditions, the mobilization of storage compounds is enhanced to provide respiratory substrates for cell survival. However, our study showed that under sugar starvation conditions, lipid breakdown is disrupted in isolated embryonic axes of white lupin and Andean lupin. This disruption can be attributed to pexophagy, the autophagic degradation of peroxisomes, and possibly lipophagy, the autophagic degradation of lipid droplets.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Linda Keil, Norbert Mehlmer, Philipp Cavelius, Daniel Garbe, Martina Haack, Manfred Ritz, Dania Awad, Thomas Brueck
Summary: This study conducted a comprehensive systems biology study on the metabolic response of D. tertiolecta to salt stress, providing insights into the short- and long-term adaptation mechanisms. The results revealed that proteins linked to the Ca2+ signaling pathway and ion channels were significantly increased in the rapid salt adaptation response, while phosphofructokinase was required for long-term adaptation. Additionally, salt stress induced upregulation of Calvin-Benson cycle-related proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Cleiton Barroso Bittencourt, Thalliton Luiz Carvalho da Silva, Jorge Candido Rodrigues Neto, Leticia Rios Vieira, Andre Pereira Leao, Jose Antonio de Aquino Ribeiro, Patricia Verardi Abdelnur, Carlos Antonio Ferreira de Sousa, Manoel Teixeira Souza Jr
Summary: Oil palm is the main source of vegetable oil, but the palm oil industry faces criticism for its unsustainable practices. Cultivating oil palm outside the rainforest zone requires artificial irrigation, and about 30% of irrigated agricultural lands worldwide also face salinity stress. Therefore, it is important for the research community to study drought and salinity together to develop superior genotypes for oil palm cultivation in new areas. Multi-Omics Integration provides an opportunity to unravel the mechanisms behind multigenic traits, such as drought and salinity tolerance.
Article
Biotechnology & Applied Microbiology
Yating Li, Longxian Lv, Jianzhong Ye, Daiqiong Fang, Ding Shi, Wenrui Wu, Qing Wang, Jingjing Wu, Liya Yang, Xiaoyuan Bian, Xianwan Jiang, Huiyong Jiang, Ren Yan, Conggao Peng, Lanjuan Li
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2019)
Review
Gastroenterology & Hepatology
Ya-Ting Li, Hong Xu, Jian-Zhong Ye, Wen-Rui Wu, Ding Shi, Dai-Qiong Fang, Yang Liu, Lan-Juan Li
WORLD JOURNAL OF GASTROENTEROLOGY
(2019)
Article
Microbiology
Xiaoyuan Bian, Wenrui Wu, Liya Yang, Longxian Lv, Qing Wang, Yating Li, Jianzhong Ye, Daiqiong Fang, Jingjing Wu, Xianwan Jiang, Ding Shi, Lanjuan Li
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Biotechnology & Applied Microbiology
Qing Wang, Kaicen Wang, Wenrui Wu, Longxian Lv, Xiaoyuan Bian, Liya Yang, Qiangqiang Wang, Yating Li, Jianzhong Ye, Daiqiong Fang, Jingjing Wu, Xianwan Jiang, Jiaojiao Xie, Yanmeng Lu, Lanjuan Li
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2020)
Article
Microbiology
Qing Wang, Jianzhong Ye, Daiqiong Fang, Longxian Lv, Wenrui Wu, Ding Shi, Yating Li, Liya Yang, Xiaoyuan Bian, Jingjing Wu, Xianwan Jiang, Kaicen Wang, Qiangqiang Wang, Mark P. Hodson, Loic M. Thibaut, Joshua W. K. Ho, Eleni Giannoulatou, Lanjuan Li
Article
Biotechnology & Applied Microbiology
Xiaoyuan Bian, Liya Yang, Wenrui Wu, Longxian Lv, Xianwan Jiang, Qing Wang, Jingjing Wu, Yating Li, Jianzhong Ye, Daiqiong Fang, Ding Shi, Kaicen Wang, Qiangqiang Wang, Yanmeng Lu, Jiaojiao Xie, Jiafeng Xia, Lanjuan Li
MICROBIAL BIOTECHNOLOGY
(2020)
Article
Microbiology
Hua Zha, Dai-Qiong Fang, Aimee van Der Reis, Kevin Chang, Li-Ya Yang, Jiao-Jiao Xie, Ding Shi, Qiao-Mai Xu, Ya-Ting Li, Lan-Juan Li
Article
Immunology
Ding Shi, Wenrui Wu, Qing Wang, Kaijin Xu, Jiaojiao Xie, Jingjing Wu, Longxian Lv, Jifang Sheng, Jing Guo, Kaicen Wang, Daiqiong Fang, Yating Li, Lanjuan Li
JOURNAL OF INFECTIOUS DISEASES
(2020)
Article
Biotechnology & Applied Microbiology
Liya Yang, Xiaoyuan Bian, Wenrui Wu, Longxian Lv, Yating Li, Jianzhong Ye, Xianwan Jiang, Qing Wang, Ding Shi, Daiqiong Fang, Jingjing Wu, Kaicen Wang, Qiangqiang Wang, Jiafeng Xia, Jiaojiao Xie, Yanmeng Lu, Lanjuan Li
MICROBIAL BIOTECHNOLOGY
(2020)
Article
Engineering, Multidisciplinary
Jingjing Wu, Daiqiong Fang, Da Man, Wenrui Wu, Qing Wang, Yating Li, Jianzhong Ye, Lanjuan Li
Article
Engineering, Multidisciplinary
Yanfei Chen, Jing Guo, Chunlei Chen, Ding Shi, Daiqiong Fang, Feng Ji, Lanjuan Li
Summary: Several studies have shown differences in oral and intestinal microbiota in patients with cirrhosis. This study analyzed the gastric mucosal microbiota of cirrhotic patients and controls, finding significantly lower H. pylori infection rates in cirrhotic patients. The non-H. pylori gastric microbiota showed heterogeneity and associations with clinical characteristics, with differences observed in composition and function among different clusters.
Article
Biotechnology & Applied Microbiology
Jiafeng Xia, Shiman Jiang, Longxian Lv, Wenrui Wu, Qiangqiang Wang, Qiaomai Xu, Jianzhong Ye, Daiqiong Fang, Yating Li, Jingjing Wu, Xiaoyuan Bian, Liya Yang, Huiyong Jiang, Kaicen Wang, Ren Yan, Lanjuan Li
Summary: Lactobacillus salivarius LI01 can directly impact the host by modulating immunity and metabolism, including restoring levels of serum biomarkers, activating Th0 cell differentiation, stimulating immune response and metabolic processes, among other effects.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Immunology
Jian Yao, Chenhong Lin, Jingjing Jiang, Xujun Zhang, Fengxia Li, Tianxing Liu, Hongyan Diao
Summary: This study identified differential expression of mRNA transcripts in asymptomatic carriers (ASCs) and CHB patients, focusing on the TGF-beta signaling pathway. The lncRNA-HEIM was found to be up-regulated in monocytes upon HBV infection and played a role in affecting the expression of TGF-beta and SMAD4. Modulating the levels of lncRNA-HEIM in monocytes significantly affected the production of TGF-beta and hepatic fibrosis, suggesting a potential therapeutic target for liver fibrosis in CHB patients.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Shiman Jiang, Jiafeng Xia, Longxian Lv, Qiangqiang Wang, Yating Li, Qiaomai Xu, Xiaoyuan Bian, Jianzhong Ye, Liya Yang, Huiyong Jiang, Ren Yan, Kaicen Wang, Daiqiong Fang, Lanjuan Li
Summary: Oral administration of P. pentosaceus LI05 can reduce body weight in rats, improve metabolism of fat and toxic substances, while also possessing anti-inflammatory and enhanced antimicrobial abilities.
Article
Gastroenterology & Hepatology
Xian-Wan Jiang, Ya-Ting Li, Jian-Zhong Ye, Long-Xian Lv, Li-Ya Yang, Xiao-Yuan Bian, Wen-Rui Wu, Jing-Jing Wu, Ding Shi, Qing Wang, Dai-Qiong Fang, Kai-Cen Wang, Qiang-Qiang Wang, Yan-Meng Lu, Jiao-Jiao Xie, Lan-Juan Li
WORLD JOURNAL OF GASTROENTEROLOGY
(2020)
Article
Biochemical Research Methods
Tanushree Halder, Elke Stroeher, Hui Liu, Yinglong Chen, Guijun Yan, Kadambot H. M. Siddique
Summary: Improving the root system of wheat is crucial for enhancing grain yield and climate resilience. This study identified proteins associated with root length and root mass in wheat using label-free quantitative proteomics. The findings revealed potential biomarkers that could be used for improving the root system of wheat.
JOURNAL OF PROTEOMICS
(2024)
Article
Biochemical Research Methods
Yinhua Pan, Quanqing Zou, Wu Yin, Zhen Huang, Yingzhu Zhao, Zongming Mo, Lihui Li, Jianrong Yang
Summary: A prognostic model of BC based on LNM-related genes was established in this study, providing guidance for prognosis evaluation and precise treatment of BC. The genes related to lymph node metastasis in BC are largely unknown and need further exploration. Searching for potential lymph node metastasis-related genes of BC will provide meaningful biomarkers for BC treatment. Our model, based on TCGA-BRCA data, effectively predicted patient outcomes and classified BC patients. The identified feature genes might have a predictive function in immunotherapy. The results of this study provide a new reference for the prognosis and treatment of BC patients with lymph node metastasis.
JOURNAL OF PROTEOMICS
(2024)
Article
Biochemical Research Methods
Qiushi Liang, Joon M. Pijnenburg, Erikjan Rijkers, Arnold G. Vulto, Ans T. van der Ploeg, Niek P. van Til, Eva C. Vlaar, Jeroen A. A. Demmers, W. W. M. Pim Pijnappel
Summary: Pompe disease is a lysosomal storage disorder characterized by glycogen accumulation in skeletal muscle, leading to profound pathology. This study showed that lentiviral gene therapy with LV-IGF2.GAAco can nearly completely correct disease-associated proteomic changes, supporting its future clinical development as a new treatment option for Pompe disease.
JOURNAL OF PROTEOMICS
(2024)
Article
Biochemical Research Methods
Chuang Liu, Wenjing Zhang, Qianli Dong, Haipeng Liu
Summary: This study fills the knowledge gap about the matrix proteins involved in the formation of mineralized exoskeletons in decapod crustaceans. By comparing with well-studied molluscan biomineralization proteins, it is proposed that decapod crustaceans evolved novel proteins while sharing some proteins with molluscs. This study provides insights into the evolution and adaptation of crustaceans and molluscs in forming their exoskeletons.
JOURNAL OF PROTEOMICS
(2024)
Article
Biochemical Research Methods
Rania D. Baka, Josipa Kules, Angelo Beletic, Vladimir Farkas, Dina Resetar Maslov, Blanka Beer Ljubic, Ivana Rubic, Vladimir Mrljak, Mark McLaughlin, David Eckersall, Zoe Polizopoulou
Summary: This study analyzed serum samples from dogs with epilepsy and identified potential markers of epilepsy, proteins involved in nerve tissue regeneration, and proteins altered by antiepileptic medication. The findings provide insight into the pathogenesis of epilepsy and the effects of medication on extracellular matrix proteins.
JOURNAL OF PROTEOMICS
(2024)
Article
Biochemical Research Methods
Viviane M. Codognoto, Fabiana F. de Souza, Thais R. Cataldi, Carlos A. Labate, Laiza S. de Camargo, Pedro H. Esteves Trindade, Roberto R. da Rosa Filho, Diego J. B. de Oliveira, Eunice Oba
Summary: This study aimed to compare urine proteomics from non- and pregnant buffaloes to identify potential biomarkers of early pregnancy. A total of 798 proteins were reported in the urine considering all groups, and the differential proteins play essential roles during pregnancy.
JOURNAL OF PROTEOMICS
(2024)