Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation

TGF-β regulates TGFBIp expression in corneal fibroblasts via miR-21, miR-181a, and Smad signaling

(2016) Seung-il Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2

(2016) Seung-il Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy in granular corneal dystrophy type 2

(2016) Seung-Il Choi et al.   EXPERIMENTAL EYE RESEARCH

Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin-deficient mice

(2016) Beatriz de Luxán-Delgado et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Protects SH-SY5Y Neuronal Cells Against Methamphetamine-Induced Endoplasmic Reticulum Stress and Apoptotic Cell Death

(2016) Pawaris Wongprayoon et al.   NEUROTOXICITY RESEARCH

Pathogenesis and treatments of TGFBI corneal dystrophies

(2016) Kyung Eun Han et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

(2015) Anna Fernández et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Glycoprotein Quality Control and Endoplasmic Reticulum Stress

(2015) Qian Wang et al.   MOLECULES

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation

(2015) Shengyi Sun et al.   NATURE CELL BIOLOGY

Lysosomal Trafficking of TGFBIp via Caveolae-Mediated Endocytosis

(2015) Seung-il Choi et al.   PLoS One

Autophagy is induced by raptor degradation via the ubiquitin/proteasome system in granular corneal dystrophy type 2

(2014) Seung-il Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival

(2014) Shengyi Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter

(2014) Shingo Suzuki et al.   Scientific Reports

Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin

(2013) María J. Tuñón et al.   JOURNAL OF PINEAL RESEARCH

Impaired autophagy and delayed autophagic clearance of transforming growth factor β-induced protein (TGFBI) in granular corneal dystrophy type 2

(2012) Seung-Il Choi et al.   Autophagy

Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp

(2012) Seung-Il Choi et al.   JOURNAL OF PINEAL RESEARCH

HRD1 Levels Increased by Zonisamide Prevented Cell Death and Caspase-3 Activation Caused by Endoplasmic Reticulum Stress in SH-SY5Y Cells

(2011) Tomohiro Omura et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Melatonin protects against oxidative stress in granular corneal dystrophy type 2 corneal fibroblasts by mechanisms that involve membrane melatonin receptors

(2011) Seung-Il Choi et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy

(2011) Chia-Chao Wu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin is able to delay endoplasmic reticulum stress-induced apoptosis in leukocytes from elderly humans

(2010) Javier Espino et al.   AGE

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

(2010) F. Allagnat et al.   DIABETOLOGIA

Deficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) in Mice Leads to Systemic Endoplasmic Reticulum Stress and Embryonic Lethality

(2010) Adam B. Francisco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

(2010) Giuseppe Paradies et al.   JOURNAL OF PINEAL RESEARCH

Decreased Catalase Expression and Increased Susceptibility to Oxidative Stress in Primary Cultured Corneal Fibroblasts from Patients with Granular Corneal Dystrophy Type II

(2009) Seung-il Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

Melatonin improves placental efficiency and birth weight and increases the placental expression of antioxidant enzymes in undernourished pregnancy

(2009) Hans G. Richter et al.   JOURNAL OF PINEAL RESEARCH

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+-mediated permeability transition and beyond in rat brain astrocytes

(2009) Mei-Jie Jou et al.   JOURNAL OF PINEAL RESEARCH

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Novel Functions of Ubiquitin Ligase HRD1 With Transmembrane and Proline-Rich Domains

(2008) Tomohiro Omura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES