Calcium influx through TRPV4 channels modulates the adherens contacts between retinal microvascular endothelial cells

Cholesterol regulates polymodal sensory transduction in Müller glia

(2017) Monika Lakk et al.   GLIA

Mouse retinal ganglion cell signalling is dynamically modulated through parallel anterograde activation of cannabinoid and vanilloid pathways

(2017) Andrew O. Jo et al.   JOURNAL OF PHYSIOLOGY-LONDON

When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor

(2017) Trine L. Toft-Bertelsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

(2017) Alejandro Berna-Erro et al.   Scientific Reports

TRPV4-AQP4 interactions ‘turbocharge’ astroglial sensitivity to small osmotic gradients

(2016) Anthony Iuso et al.   Channels

Modulation of TRPV4 by diverse mechanisms

(2016) W.G. Darby et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

 -Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function

(2016) N. Ziegler et al.   JOURNAL OF NEUROSCIENCE

Store-Operated Calcium Entry in Muller Glia Is Controlled by Synergistic Activation of TRPC and Orai Channels

(2016) T. Molnar et al.   JOURNAL OF NEUROSCIENCE

Vasculo-Neuronal Coupling: Retrograde Vascular Communication to Brain Neurons

(2016) Ki Jung Kim et al.   JOURNAL OF NEUROSCIENCE

TRPV4: Molecular Conductor of a Diverse Orchestra

(2016) John P. M. White et al.   PHYSIOLOGICAL REVIEWS

Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels

(2016) Andrew O. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye

(2016) Daniel A. Ryskamp et al.   Scientific Reports

Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4

(2015) Karthik Suresh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TRPV4 regulates the integrity of the blood-cerebrospinal fluid barrier and modulates transepithelial protein transport

(2015) Keishi Narita et al.   FASEB JOURNAL

TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Muller Glia

(2015) A. O. Jo et al.   JOURNAL OF NEUROSCIENCE

Transient Receptor Potential Channels in the Vasculature

(2015) Scott Earley et al.   PHYSIOLOGICAL REVIEWS

Opposing actions of TRPV4 channel activation in the lung vasculature

(2015) Sun-Kui Ke et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

(2015) Kevin Monaghan et al.   PLoS One

Role of MMP2 and MMP9 in TRPV4-induced lung injury

(2014) Patricia C. Villalta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Swelling and Eicosanoid Metabolites Differentially Gate TRPV4 Channels in Retinal Neurons and Glia

(2014) D. A. Ryskamp et al.   JOURNAL OF NEUROSCIENCE

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses

(2013) K. M. Dunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions

(2013) Ingeborg Klaassen et al.   PROGRESS IN RETINAL AND EYE RESEARCH

A dynamic real-time method for monitoring epithelial barrier function in vitro

(2012) Mingjiao Sun et al.   ANALYTICAL BIOCHEMISTRY

Positive feedback control between STIM1 and NFATc3 is required for C2C12 myoblast differentiation

(2012) Tam Thi Thanh Phuong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells

(2012) C. Giampietro et al.   BLOOD

A bigger picture: classical cadherins and the dynamic actin cytoskeleton

(2012) Aparna Ratheesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Low intravascular pressure activates endothelial cell TRPV4 channels, local Ca2+ events, and IKCa channels, reducing arteriolar tone

(2012) P. Bagher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the retinal vascular endothelial cell in ocular disease

(2012) Arpita S. Bharadwaj et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function

(2012) S. K. Sonkusare et al.   SCIENCE

Activation of TRPV4 Strengthens the Tight-Junction Barrier in Human Epidermal Keratinocytes

(2012) Y. Akazawa et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells

(2011) Xin Ma et al.   CELL CALCIUM

Phosphorylation on the Ser 824 residue of TRPV4 prefers to bind with F-actin than with microtubules to expand the cell surface area

(2011) Sung Hwa Shin et al.   CELLULAR SIGNALLING

A Hitchhiker's Guide to Mechanobiology

(2011) Jeroen Eyckmans et al.   DEVELOPMENTAL CELL

Cerebral Arteriogenesis is Enhanced by Pharmacological as Well as Fluid-Shear-Stress Activation of the Trpv4 Calcium Channel

(2011) W. Schierling et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

The Polymodal Ion Channel Transient Receptor Potential Vanilloid 4 Modulates Calcium Flux, Spiking Rate, and Apoptosis of Mouse Retinal Ganglion Cells

(2011) D. A. Ryskamp et al.   JOURNAL OF NEUROSCIENCE

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Activation of TRPV1 by Dietary Capsaicin Improves Endothelium-Dependent Vasorelaxation and Prevents Hypertension

(2010) Dachun Yang et al.   Cell Metabolism

Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface β1 integrins

(2010) Benjamin D. Matthews et al.   Integrative Biology

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure

(2009) Scott Earley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Phospholipase D2 regulates endothelial permeability through cytoskeleton reorganization and occludin downregulation

(2009) Caroline Zeiller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling

(2009) Charles K. Thodeti et al.   CIRCULATION RESEARCH

Transient Receptor Potential Vanilloid Type 4–Deficient Mice Exhibit Impaired Endothelium-Dependent Relaxation Induced by Acetylcholine In Vitro and In Vivo

(2009) David X. Zhang et al.   HYPERTENSION

Activation of the TRPV4 Ion Channel Is Enhanced by Phosphorylation

(2009) Hueng-Chuen Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation

(2008) Annemarieke E. Loot et al.   CARDIOVASCULAR RESEARCH

Role of Caveolar Compartmentation in Endothelium-Derived Hyperpolarizing Factor–Mediated Relaxation

(2008) J. Saliez et al.   CIRCULATION

Trpv4 induces collateral vessel growth during regeneration of the arterial circulation

(2008) Christian Troidl et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

(2008) K. S. Thorneloe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

(2008) R. N. Willette et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

(2008) Christopher A Jones et al.   NATURE MEDICINE