Inhibition of fracture healing in the presence of contamination by Staphylococcus aureus : Effects of growth state and immune response

Macrophages in bone fracture healing: Their essential role in endochondral ossification

(2018) Claudia Schlundt et al.   BONE

Staphylococcal Biofilms and Immune Polarization During Prosthetic Joint Infection

(2017) Casey M. Gries et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Collaborative Interferon-γ and Interleukin-17 Signaling Protects the Oral Mucosa from Staphylococcus aureus

(2016) Jobert G. Barin et al.   AMERICAN JOURNAL OF PATHOLOGY

Reactive Oxygen Species and Neutrophil Function

(2016) Christine C. Winterbourn et al.   Annual Review of Biochemistry

Gel-Entrapped Staphylococcus aureus Bacteria as Models of Biofilm Infection Exhibit Growth in Dense Aggregates, Oxygen Limitation, Antibiotic Tolerance, and Heterogeneous Gene Expression

(2016) Breana Pabst et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria

(2016) Claes Dahlgren et al.   BIOCHEMICAL PHARMACOLOGY

Monitoring immune responses in a mouse model of fracture fixation with and without Staphylococcus aureus osteomyelitis

(2016) Edward T.J. Rochford et al.   BONE

Neutrophils contribute to fracture healing by synthesizing fibronectin + extracellular matrix rapidly after injury

(2016) Okan W. Bastian et al.   CLINICAL IMMUNOLOGY

Interleukin-17A (IL-17A) and IL-17F Are Critical for Antimicrobial Peptide Production and Clearance of Staphylococcus aureus Nasal Colonization

(2016) Nathan K. Archer et al.   INFECTION AND IMMUNITY

Impact ofsarAand Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus

(2016) Allister J. Loughran et al.   INFECTION AND IMMUNITY

Noncontiguous and open fractures of the lower extremity: Epidemiology, complications, and unplanned procedures

(2016) Andrew T. Chen et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Synergistic Action of IL-8 and Bone Marrow Concentrate on Cartilage Regeneration Through Upregulation of Chondrogenic Transcription Factors

(2016) Dong Suk Yoon et al.   TISSUE ENGINEERING PART A

Convergence of Staphylococcus aureus Persister and Biofilm Research: Can Biofilms Be Defined as Communities of Adherent Persister Cells?

(2016) Elaine M. Waters et al.   PLoS Pathogens

Battlefield Orthopaedic Injuries Cause the Majority of Long-term Disabilities

(2016) Jessica D. Cross et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Mesenchymal stromal cell implantation for stimulation of long bone healing aggravates Staphylococcus aureus induced osteomyelitis

(2015) Elisabeth Seebach et al.   Acta Biomaterialia

Regulatory T-cell Subsets with Acquired Functional Impairment: Important Indicators of Disease Severity in Atopic Dermatitis

(2015) K Gáspár et al.   ACTA DERMATO-VENEREOLOGICA

Soluble factors from biofilms of wound pathogens modulate human bone marrow-derived stromal cell differentiation, migration, angiogenesis, and cytokine secretion

(2015) Catherine L Ward et al.   BMC MICROBIOLOGY

Rifamycin Derivatives Are Effective Against Staphylococcal Biofilms In Vitro and Elutable From PMMA

(2015) Carlos J. Sanchez et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Biofilm Formation by Staphylococcus aureus Isolates from Skin and Soft Tissue Infections

(2015) Jakub Kwiecinski et al.   CURRENT MICROBIOLOGY

Defensins: “Simple” antimicrobial peptides or broad-spectrum molecules?

(2015) Meggy Suarez-Carmona et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response

(2015) J. K. Chan et al.   EMBO Molecular Medicine

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus

(2015) Liana C. Chan et al.   INFECTION AND IMMUNITY

Risk factors for long bone fracture non-union: a stratification approach based on the level of the existing scientific evidence

(2015) Emmanuele Santolini et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Interleukin-17 and innate immunity in infections and chronic inflammation

(2015) Natasa Isailovic et al.   JOURNAL OF AUTOIMMUNITY

Macrophages Promote Osteoblastic Differentiation In Vivo: Implications in Fracture Repair and Bone Homeostasis

(2015) Linda Vi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

IL-12 Promotes Myeloid-Derived Suppressor Cell Recruitment and Bacterial Persistence duringStaphylococcus aureusOrthopedic Implant Infection

(2015) Cortney E. Heim et al.   JOURNAL OF IMMUNOLOGY

Anti-biofilm activity of ultrashort cinnamic acid peptide derivatives against medical device-related pathogens

(2015) Garry Laverty et al.   JOURNAL OF PEPTIDE SCIENCE

Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection

(2015) Aimee D. Wilde et al.   PLoS Pathogens

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

(2015) Aisling F. Brown et al.   PLoS Pathogens

Combined local and systemic antibiotic delivery improves eradication of wound contamination

(2015) B. C. C. Rand et al.   Bone & Joint Journal

Antibacterial and anti-biofilm activities of thiazolidione derivatives against clinical staphylococcus strains

(2015) Huayong Liu et al.   Emerging Microbes & Infections

Myeloid-Derived Suppressor Cells: Paradoxical Roles in Infection and Immunity

(2015) Jun Dai et al.   Journal of Innate Immunity

Statins and Antimicrobial Effects: Simvastatin as a Potential Drug against Staphylococcus aureus Biofilm

(2015) Talita Signoreti Graziano et al.   PLoS One

Microbiology and injury characteristics in severe open tibia fractures from combat

(2015) Travis C. Burns et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Fracture Healing via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Early Endochondral Ossification

(2014) Liza J. Raggatt et al.   AMERICAN JOURNAL OF PATHOLOGY

d-Amino Acids Enhance the Activity of Antimicrobials against Biofilms of Clinical Wound Isolates of Staphylococcus aureus and Pseudomonas aeruginosa

(2014) Carlos J. Sanchez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bone regeneration in a massive rat femur defect through endochondral ossification achieved with chondrogenically differentiated MSCs in a degradable scaffold

(2014) Noriko Harada et al.   BIOMATERIALS

Myeloid-Derived Suppressor Cells Contribute to Staphylococcus aureus Orthopedic Biofilm Infection

(2014) C. E. Heim et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus Infection of Mice Expands a Population of Memory    T Cells That Are Protective against Subsequent Infection

(2014) A. G. Murphy et al.   JOURNAL OF IMMUNOLOGY

Dual Impact of Live Staphylococcus aureus on the Osteoclast Lineage, Leading to Increased Bone Resorption

(2014) Sophie Trouillet-Assant et al.   JOURNAL OF INFECTIOUS DISEASES

MCP/CCR2 Signaling Is Essential for Recruitment of Mesenchymal Progenitor Cells during the Early Phase of Fracture Healing

(2014) Masahiro Ishikawa et al.   PLoS One

Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response

(2014) César de la Fuente-Núñez et al.   PLoS Pathogens

Effects of Bacteriocins on Methicillin-Resistant Staphylococcus aureus Biofilm

(2013) Ken-ichi Okuda et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of local delivery of d-amino acids from biofilm-dispersive scaffolds on infection in contaminated rat segmental defects

(2013) Carlos J. Sanchez et al.   BIOMATERIALS

Biofilm formation by clinical isolates and the implications in chronic infections

(2013) Carlos J Sanchez et al.   BMC INFECTIOUS DISEASES

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Staphylococcal and Streptococcal Superantigen Exotoxins

(2013) A. R. Spaulding et al.   CLINICAL MICROBIOLOGY REVIEWS

Staphylococcal enterotoxin B induced expression of IL-17A in nasal epithelial cells and its association with pathogenesis of nasal polyposis

(2013) Jun Jin et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Inflammatory Monocytes Recruited to Allergic Skin Acquire an Anti-inflammatory M2 Phenotype via Basophil-Derived Interleukin-4

(2013) Mayumi Egawa et al.   IMMUNITY

Clearance of Staphylococcus aureus Nasal Carriage Is T Cell Dependent and Mediated through Interleukin-17A Expression and Neutrophil Influx

(2013) Nathan K. Archer et al.   INFECTION AND IMMUNITY

Optimizing combination rifampin therapy for staphylococcal osteoarticular infections

(2013) Guillaume Coiffier et al.   JOINT BONE SPINE

Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia

(2013) Raymond Schuch et al.   JOURNAL OF INFECTIOUS DISEASES

Implant-associated localized osteitis in murine femur fracture by biofilm formingStaphylococcus aureus: A novel experimental model

(2013) Ceylan D. Windolf et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Local Antibiotic Delivery by a Bioabsorbable Gel Is Superior to PMMA Bead Depot in Reducing Infection in an Open Fracture Model

(2013) Jowan G. Penn-Barwell et al.   JOURNAL OF ORTHOPAEDIC TRAUMA

In vitro pharmacokinetics of antimicrobial cationic peptides alone and in combination with antibiotics against methicillin resistant Staphylococcus aureus biofilms

(2013) Sibel Dosler et al.   PEPTIDES

Early antibiotics and debridement independently reduce infection in an open fracture model

(2012) J. G. Penn-Barwell et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Staphylococcus aureus Persisters Tolerant to Bactericidal Antibiotics

(2012) Sabrina Lechner et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Staphylococcus aureus Protein A Plays a Critical Role in Mediating Bone Destruction and Bone Loss in Osteomyelitis

(2012) Amro Widaa et al.   PLoS One

MyD88-Dependent Signaling Influences Fibrosis and Alternative Macrophage Activation during Staphylococcus aureus Biofilm Infection

(2012) Mark L. Hanke et al.   PLoS One

Epicutaneous Exposure to Staphylococcal Superantigen Enterotoxin B Enhances Allergic Lung Inflammation via an IL-17A Dependent Mechanism

(2012) Jinho Yu et al.   PLoS One

Regulatory T-Cells: Diverse Phenotypes Integral to Immune Homeostasis and Suppression

(2012) Richard A. Peterson   TOXICOLOGIC PATHOLOGY

Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus

(2011) Scott N Dean et al.   BMC MICROBIOLOGY

Human Early Fracture Hematoma Is Characterized by Inflammation and Hypoxia

(2011) Paula Kolar et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Dual delivery of an antibiotic and a growth factor addresses both the microbiological and biological challenges of contaminated bone fractures

(2011) Joseph C Wenke et al.   Expert Opinion on Drug Delivery

Murine Immune Response to a ChronicStaphylococcus aureusBiofilm Infection

(2011) Ranjani Prabhakara et al.   INFECTION AND IMMUNITY

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

(2011) Kylie A Alexander et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Staphylococcus aureus Biofilms Prevent Macrophage Phagocytosis and Attenuate Inflammation In Vivo

(2011) L. R. Thurlow et al.   JOURNAL OF IMMUNOLOGY

Protective role of IL-1β against post-arthroplasty Staphylococcus aureus infection

(2011) Nicholas M. Bernthal et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Staphylococcus aureus Protein A Binds to Osteoblasts and Triggers Signals That Weaken Bone in Osteomyelitis

(2011) Tania Claro et al.   PLoS One

Prevention of Infections Associated With Combat-Related Extremity Injuries

(2011) Clinton K. Murray et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Rehospitalization After Combat Injury

(2011) Brendan D. Masini et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

Specificity in Killing Pathogens Is Mediated by Distinct Repertoires of Human Neutrophil Peptides

(2010) Andreas Cederlund et al.   Journal of Innate Immunity

Sustained release of vancomycin from a new biodegradable glue to prevent methicillin-resistant Staphylococcus aureus graft infection☆

(2010) Manabu Morishima et al.   Interactive Cardiovascular and Thoracic Surgery

High Levels of Tumor Necrosis Factor-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing

(2009) Jazia Alblowi et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-6 is essential for Staphylococcal exotoxin B-induced T regulatory cell insufficiency in nasal polyps

(2009) G. Xu et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Direct and alternative antimicrobial mechanisms of neutrophil-derived granule proteins

(2009) Oliver Soehnlein   JOURNAL OF MOLECULAR MEDICINE-JMM

Resource Utilization and Disability Outcome Assessment of Combat Casualties From Operation Iraqi Freedom and Operation Enduring Freedom

(2009) Brendan D Masini et al.   JOURNAL OF ORTHOPAEDIC TRAUMA

Th1-Th17 Cells Mediate Protective Adaptive Immunity against Staphylococcus aureus and Candida albicans Infection in Mice

(2009) Lin Lin et al.   PLoS Pathogens

Combat Wounds in Operation Iraqi Freedom and Operation Enduring Freedom

(2009) Brett D. Owens et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model

(2008) Maren von Köckritz-Blickwede et al.   AMERICAN JOURNAL OF PATHOLOGY

The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29

(2008) Scott Commins et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Biofilm Formation Induces C3a Release and ProtectsStaphylococcus epidermidisfrom IgG and Complement Deposition and from Neutrophil‐Dependent Killing

(2008) Sascha A. Kristian et al.   JOURNAL OF INFECTIOUS DISEASES

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens