Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitness cost of antibiotic susceptibility during bacterial infection

(2015) Damien Roux et al.   Science Translational Medicine

Glycolytic Dependency of High-Level Nitric Oxide Resistance and Virulence in Staphylococcus aureus

(2015) Nicholas P. Vitko et al.   mBio

Genetic Basis of Persister Tolerance to Aminoglycosides in Escherichia coli

(2015) Yue Shan et al.   mBio

Genome-Wide Identification of Klebsiella pneumoniae Fitness Genes during Lung Infection

(2015) Michael A. Bachman et al.   mBio

Inter- and Intraspecies Metabolite Exchange Promotes Virulence of Antibiotic-Resistant Staphylococcus aureus

(2014) Neal D. Hammer et al.   Cell Host & Microbe

Thepsmα Locus Regulates Production of Staphylococcus aureus Alpha-Toxin during Infection

(2014) Bryan J. Berube et al.   INFECTION AND IMMUNITY

Direct measurement of local oxygen concentration in the bone marrow of live animals

(2014) Joel A. Spencer et al.   NATURE

Genes Contributing to Staphylococcus aureus Fitness in Abscess- and Infection-Related Ecologies

(2014) M. D. Valentino et al.   mBio

Genome-Wide Mutant Fitness Profiling Identifies Nutritional Requirements for Optimal Growth of Yersinia pestis in Deep Tissue

(2014) S. G. Palace et al.   mBio

Discovery of Antivirulence Agents against Methicillin-Resistant Staphylococcus aureus

(2013) Varandt Khodaverdian et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung

(2013) S. M. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Approaches to querying bacterial genomes with transposon-insertion sequencing

(2013) Lars Barquist et al.   RNA Biology

The Staphylococcus aureus SrrAB Two-Component System Promotes Resistance to Nitrosative Stress and Hypoxia

(2013) T. L. Kinkel et al.   mBio

Genome-Wide Detection of Fitness Genes in Uropathogenic Escherichia coli during Systemic Infection

(2013) Sargurunathan Subashchandrabose et al.   PLoS Pathogens

A Comprehensive Analysis of In Vitro and In Vivo Genetic Fitness of Pseudomonas aeruginosa Using High-Throughput Sequencing of Transposon Libraries

(2013) David Skurnik et al.   PLoS Pathogens

Gene Fitness Landscapes of Vibrio cholerae at Important Stages of Its Life Cycle

(2013) Heather D. Kamp et al.   PLoS Pathogens

The role of oxygen during fracture healing

(2012) Chuanyong Lu et al.   BONE

Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA

(2012) F. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

AirSR, a [2Fe-2S] Cluster-Containing Two-Component System, Mediates Global Oxygen Sensing and Redox Signaling in Staphylococcus aureus

(2011) Fei Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transcription and Translation Products of the Cytolysin Gene psm-mec on the Mobile Genetic Element SCCmec Regulate Staphylococcus aureus Virulence

(2011) Chikara Kaito et al.   PLoS Pathogens

Redox sensing by a Rex-family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus

(2010) Martin Pagels et al.   MOLECULAR MICROBIOLOGY

Identification of Genes Involved in Polysaccharide-Independent Staphylococcus aureus Biofilm Formation

(2010) Blaise R. Boles et al.   PLoS One

Trends in the Incidence of Methicillin‐ResistantStaphylococcus aureusInfection in Children’s Hospitals in the United States

(2009) Jeffrey S. Gerber et al.   CLINICAL INFECTIOUS DISEASES

Interaction of staphylococci with bone

(2009) John A. Wright et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Staphylococcus aureus SarA is a regulatory protein responsive to redox and pH that can support bacteriophage lambda integrase-mediated excision/recombination

(2009) David F. Fujimoto et al.   MOLECULAR MICROBIOLOGY

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

(2009) Tim van Opijnen et al.   NATURE METHODS

Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology

USA300 is the Predominant Genotype Causing Staphylococcus aureus Septic Arthritis in Children

(2009) Maria A. Carrillo-Marquez et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Improved lux reporters for use in Staphylococcus aureus

(2009) Lili Rosana Mesak et al.   PLASMID

agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides

(2009) E. Geisinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Taking a Toll on the bones: Regulation of bone metabolism by innate immune regulators

(2008) Zvi Bar-Shavit   AUTOIMMUNITY

RNAIII-Independent Target Gene Control by the agr Quorum-Sensing System: Insight into the Evolution of Virulence Regulation in Staphylococcus aureus

(2008) Shu Y. Queck et al.   MOLECULAR CELL