HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency
Authors
Keywords
HIV latency, Epigenetic silencing, Humanized mice, Microglial cell
Journal
JOURNAL OF NEUROVIROLOGY
Volume 24, Issue 2, Pages 192-203
Publisher
Springer Nature
Online
2017-12-19
DOI
10.1007/s13365-017-0604-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells
- (2017) David Alvarez-Carbonell et al. Retrovirology
- HIV Latency: Should We Shock or Lock?
- (2017) Gilles Darcis et al. TRENDS IN IMMUNOLOGY
- Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency
- (2017) Kien Nguyen et al. mBio
- The Molecular Basis for Human Immunodeficiency Virus Latency
- (2017) Uri Mbonye et al. Annual Review of Virology
- Multiple Origins of Virus Persistence during Natural Control of HIV Infection
- (2016) Eli A. Boritz et al. CELL
- Macrophages sustain HIV replication in vivo independently of T cells
- (2016) Jenna B. Honeycutt et al. JOURNAL OF CLINICAL INVESTIGATION
- New tools for studying microglia in the mouse and human CNS
- (2016) Mariko L. Bennett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 Reservoirs During Suppressive Therapy
- (2016) Kirston Barton et al. TRENDS IN MICROBIOLOGY
- HIV-1 Eradication: Early Trials (and Tribulations)
- (2016) Adam M. Spivak et al. TRENDS IN MOLECULAR MEDICINE
- Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis
- (2016) Qing Li et al. Scientific Reports
- HIV eradication symposium: will the brain be left behind?
- (2015) B. J. Brew et al. JOURNAL OF NEUROVIROLOGY
- Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors
- (2015) Jianbin Wang et al. NATURE BIOTECHNOLOGY
- The Potential of the CNS as a Reservoir for HIV-1 Infection: Implications for HIV Eradication
- (2015) Alessandro F. Fois et al. Current HIV/AIDS Reports
- Compartmentalization, Viral Evolution, and Viral Latency of HIV in the CNS
- (2015) Maria M. Bednar et al. Current HIV/AIDS Reports
- Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice
- (2015) Michael D Boska et al. Molecular Neurodegeneration
- Signaling Mechanism of HIV-1 gp120 and Virion-Induced IL-1 Release in Primary Human Macrophages
- (2014) R. Cheung et al. JOURNAL OF IMMUNOLOGY
- Negative Elongation Factor Is Required for the Maintenance of Proviral Latency but Does Not Induce Promoter-Proximal Pausing of RNA Polymerase II on the HIV Long Terminal Repeat
- (2014) J. K. Jadlowsky et al. MOLECULAR AND CELLULAR BIOLOGY
- An Example of Genetically Distinct HIV Type 1 Variants in Cerebrospinal Fluid and Plasma During Suppressive Therapy
- (2013) Viktor Dahl et al. JOURNAL OF INFECTIOUS DISEASES
- Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs
- (2013) Christine Katlama et al. LANCET
- Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation
- (2013) Fiona L Wilkinson et al. MOLECULAR THERAPY
- Myeloid/Microglial Driven Autologous Hematopoietic Stem Cell Gene Therapy Corrects a Neuronopathic Lysosomal Disease
- (2013) Ana Sergijenko et al. MOLECULAR THERAPY
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- Molecular and pathologic insights from latent HIV-1 infection in the human brain
- (2013) P. Desplats et al. NEUROLOGY
- Origin and differentiation of microglia
- (2013) Florent Ginhoux et al. Frontiers in Cellular Neuroscience
- HIV-1 eradication strategies
- (2013) Janet D. Siliciano et al. Current Opinion in HIV and AIDS
- Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes
- (2013) Uri R. Mbonye et al. PLoS Pathogens
- Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and induces human immunodeficiency virus (HIV) transcription in human microglial cells
- (2012) Emily S. Wires et al. JOURNAL OF NEUROVIROLOGY
- Wild-type microglia arrest pathology in a mouse model of Rett syndrome
- (2012) Noël C. Derecki et al. NATURE
- Phenelzine (Monoamine Oxidase Inhibitor) Increases Production of Nitric Oxide and Proinflammatory Cytokines via the NF-κB Pathway in Lipopolysaccharide-Activated Microglia Cells
- (2012) Hwan-Suck Chung et al. NEUROCHEMICAL RESEARCH
- Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
- (2012) A. Capotondo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells
- (2012) N. H. Varvel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain Cell Reservoirs of Latent Virus in Presymptomatic HIV-Infected Individuals
- (2011) Katherine A. Thompson et al. AMERICAN JOURNAL OF PATHOLOGY
- Toll-like Receptor Expression and Activation in Astroglia: Differential Regulation by HIV-1 Tat, gp120, and Morphine
- (2011) Nazira El-Hage et al. IMMUNOLOGICAL INVESTIGATIONS
- T-Cell Receptor Signaling Enhances Transcriptional Elongation from Latent HIV Proviruses by Activating P-TEFb through an ERK-Dependent Pathway
- (2011) Young Kyeung Kim et al. JOURNAL OF MOLECULAR BIOLOGY
- Loss of Neuronal Integrity during Progressive HIV-1 Infection of Humanized Mice
- (2011) P. K. Dash et al. JOURNAL OF NEUROSCIENCE
- A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
- (2011) Masoud Vedadi et al. Nature Chemical Biology
- LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing
- (2011) V. Le Douce et al. NUCLEIC ACIDS RESEARCH
- Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)
- (2011) Naoki Sakane et al. PLoS Pathogens
- HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types
- (2011) Gretja Schnell et al. PLoS Pathogens
- Links between Progressive HIV-1 Infection of Humanized Mice and Viral Neuropathogenesis
- (2010) Santhi Gorantla et al. AMERICAN JOURNAL OF PATHOLOGY
- HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection
- (2010) G. HERBEIN et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- A new method to isolate microglia from adult mice and culture them for an extended period of time
- (2010) Simon Moussaud et al. JOURNAL OF NEUROSCIENCE METHODS
- Comparative Analysis of Small Molecules and Histone Substrate Analogues as LSD1 Lysine Demethylase Inhibitors
- (2010) Jeffrey C. Culhane et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
- (2010) Nathalia Holt et al. NATURE BIOTECHNOLOGY
- Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia
- (2009) Melissa J. Churchill et al. ANNALS OF NEUROLOGY
- Role of Tat Protein in HIV Neuropathogenesis
- (2009) Wenxue Li et al. NEUROTOXICITY RESEARCH
- Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
- (2009) N. Cartier et al. SCIENCE
- Compartmentalized Human Immunodeficiency Virus Type 1 Originates from Long-Lived Cells in Some Subjects with HIV-1–Associated Dementia
- (2009) Gretja Schnell et al. PLoS Pathogens
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started