Calcium dependence of spontaneous neurotransmitter release

Synaptotagmin2 (Syt2) Drives Fast Release Redundantly with Syt1 at the Output Synapses of Parvalbumin-Expressing Inhibitory Neurons

(2017) Brice Bouhours et al.   JOURNAL OF NEUROSCIENCE

Distinct Actions of Voltage-Activated Ca 2+ Channel Block on Spontaneous Release at Excitatory and Inhibitory Central Synapses

(2017) Timur Tsintsadze et al.   JOURNAL OF NEUROSCIENCE

Synaptotagmin 2 Is the Fast Ca 2+ Sensor at a Central Inhibitory Synapse

(2017) Chong Chen et al.   Cell Reports

Should I stop or should I go? The role of complexin in neurotransmitter release

(2016) Thorsten Trimbuch et al.   NATURE REVIEWS NEUROSCIENCE

Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels

(2016) Dong-Dong Liu et al.   Scientific Reports

Synaptotagmin-7 Is Essential for Ca2+-Triggered Delayed Asynchronous Release But Not for Ca2+-Dependent Vesicle Priming in Retinal Ribbon Synapses

(2015) F. Luo et al.   JOURNAL OF NEUROSCIENCE

Complexin Stabilizes Newly Primed Synaptic Vesicles and Prevents Their Premature Fusion at the Mouse Calyx of Held Synapse

(2015) S. Chang et al.   JOURNAL OF NEUROSCIENCE

Spontaneous Vesicle Release Is Not Tightly Coupled to Voltage-Gated Calcium Channel-Mediated Ca2+ Influx and Is Triggered by a Ca2+ Sensor Other Than Synaptotagmin-2 at the Juvenile Mice Calyx of Held Synapses

(2015) J. Dai et al.   JOURNAL OF NEUROSCIENCE

Nanoscale Distribution of Presynaptic Ca 2+ Channels and Its Impact on Vesicular Release during Development

(2015) Yukihiro Nakamura et al.   NEURON

Molecular Underpinnings of Synaptic Vesicle Pool Heterogeneity

(2015) Devon C. Crawford et al.   TRAFFIC

Innervation by a GABAergic Neuron Depresses Spontaneous Release in Glutamatergic Neurons and Unveils the Clamping Phenotype of Synaptotagmin-1

(2014) K. D. B. Wierda et al.   JOURNAL OF NEUROSCIENCE

The proteome of the presynaptic active zone from mouse brain

(2014) Jens Weingarten et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Control and Plasticity of the Presynaptic Action Potential Waveform at Small CNS Nerve Terminals

(2014) Michael B. Hoppa et al.   NEURON

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment

(2014) Huisheng Liu et al.   eLife

Complexin inhibits spontaneous release and synchronizes Ca2+-triggered synaptic vesicle fusion by distinct mechanisms

(2014) Ying Lai et al.   eLife

Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels

(2013) Yaroslav S Ermolyuk et al.   NATURE NEUROSCIENCE

Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release

(2013) Taulant Bacaj et al.   NEURON

Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes

(2013) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium regulation of spontaneous and asynchronous neurotransmitter release

(2012) Stephen M. Smith et al.   CELL CALCIUM

Miniature IPSCs in Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca2+ Channels via Microdomain Coupling

(2012) S. P. Goswami et al.   JOURNAL OF NEUROSCIENCE

Independent Vesicle Pools Underlie Different Modes of Release during Neuronal Development

(2012) L. C. Andreae et al.   JOURNAL OF NEUROSCIENCE

Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA

(2012) Courtney Williams et al.   NATURE NEUROSCIENCE

Independent Regulation of Basal Neurotransmitter Release Efficacy by Variable Ca2+ Influx and Bouton Size at Small Central Synapses

(2012) Yaroslav S. Ermolyuk et al.   PLOS BIOLOGY

Calcium cooperativity of exocytosis as a measure of Ca2+ channel domain overlap

(2011) Victor Matveev et al.   BRAIN RESEARCH

Complexin Has Opposite Effects on Two Modes of Synaptic Vesicle Fusion

(2011) Jesse A. Martin et al.   CURRENT BIOLOGY

Differential regulation of spontaneous and evoked neurotransmitter release at central synapses

(2011) Denise MO Ramirez et al.   CURRENT OPINION IN NEUROBIOLOGY

Mechanism of Spontaneous Activity in Afferent Neurons of the Zebrafish Lateral-Line Organ

(2011) J. G. Trapani et al.   JOURNAL OF NEUROSCIENCE

Single-Pixel Optical Fluctuation Analysis of Calcium Channel Function in Active Zones of Motor Nerve Terminals

(2011) F. Luo et al.   JOURNAL OF NEUROSCIENCE

Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor

(2011) N. P. Vyleta et al.   JOURNAL OF NEUROSCIENCE

Sharp Ca2+ Nanodomains beneath the Ribbon Promote Highly Synchronous Multivesicular Release at Hair Cell Synapses

(2011) C. W. Graydon et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism

(2011) Mackenzie E. Hofmann et al.   JOURNAL OF PHYSIOLOGY-LONDON

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Nanodomain coupling between Ca2+ channels and sensors of exocytosis at fast mammalian synapses

(2011) Emmanuel Eggermann et al.   NATURE REVIEWS NEUROSCIENCE

Doc2 Supports Spontaneous Synaptic Transmission by a Ca2+-Independent Mechanism

(2011) Zhiping P. Pang et al.   NEURON

Increased Coupled Gating of L-Type Ca 2+ Channels During Hypertension and Timothy Syndrome

(2010) Manuel F. Navedo et al.   CIRCULATION RESEARCH

DOC2B, C2 Domains, and Calcium: A Tale of Intricate Interactions

(2010) Reut Friedrich et al.   MOLECULAR NEUROBIOLOGY

N-type Ca2+ channels carry the largest current: implications for nanodomains and transmitter release

(2010) Alexander M Weber et al.   NATURE NEUROSCIENCE

Ca2+-dependent enhancement of release by subthreshold somatic depolarization

(2010) Jason M Christie et al.   NATURE NEUROSCIENCE

Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity

(2010) Mingshan Xue et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Presynaptic External Calcium Signaling Involves the Calcium-Sensing Receptor in Neocortical Nerve Terminals

(2010) Wenyan Chen et al.   PLoS One

Doc2b Is a High-Affinity Ca2+ Sensor for Spontaneous Neurotransmitter Release

(2010) A. J. Groffen et al.   SCIENCE

Autapses and Networks of Hippocampal Neurons Exhibit Distinct Synaptic Transmission Phenotypes in the Absence of Synaptotagmin I

(2009) H. Liu et al.   JOURNAL OF NEUROSCIENCE

The Unitary Event Underlying Multiquantal EPSCs at a Hair Cell's Ribbon Synapse

(2009) G.-L. Li et al.   JOURNAL OF NEUROSCIENCE

Complexin-I Is Required for High-Fidelity Transmission at the Endbulb of Held Auditory Synapse

(2009) N. Strenzke et al.   JOURNAL OF NEUROSCIENCE

Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release

(2009) Jun Xu et al.   NATURE NEUROSCIENCE

A small number of open Ca2+ channels trigger transmitter release at a central GABAergic synapse

(2009) Iancu Bucurenciu et al.   NATURE NEUROSCIENCE

Recruitment of N-Type Ca2+ Channels during LTP Enhances Low Release Efficacy of Hippocampal CA1 Perforant Path Synapses

(2009) Mohsin S. Ahmed et al.   NEURON

Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion

(2009) A. Maximov et al.   SCIENCE

AKAP150 Is Required for Stuttering Persistent Ca 2+ Sparklets and Angiotensin II–Induced Hypertension

(2008) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Phorbol Esters Modulate Spontaneous and Ca2+-Evoked Transmitter Release via Acting on Both Munc13 and Protein Kinase C

(2008) X. Lou et al.   JOURNAL OF NEUROSCIENCE

Nanodomain Coupling between Ca2+ Channels and Ca2+ Sensors Promotes Fast and Efficient Transmitter Release at a Cortical GABAergic Synapse

(2008) Iancu Bucurenciu et al.   NEURON

Fast Inhibition of Glutamate-Activated Currents by Caffeine

(2008) Nicholas P. Vyleta et al.   PLoS One

Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system

(2008) M. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA