Myelin as an inflammatory mediator: Myelin interactions with complement, macrophages, and microglia in spinal cord injury

Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury

(2017) Y. Zhu et al.   JOURNAL OF NEUROSCIENCE

Compression Decreases Anatomical and Functional Recovery and Alters Inflammation after Contusive Spinal Cord Injury

(2017) Michael B. Orr et al.   JOURNAL OF NEUROTRAUMA

Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment

(2017) John C. Gensel et al.   Scientific Reports

Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia

(2016) Tamjeed A. Siddiqui et al.   Journal of Neuroinflammation

TREM2 regulates microglial cell activation in response to demyelination in vivo

(2015) Claudia Cantoni et al.   ACTA NEUROPATHOLOGICA

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

(2015) Christina M. Lill et al.   Alzheimers & Dementia

Macrophage activation and its role in repair and pathology after spinal cord injury

(2015) John C. Gensel et al.   BRAIN RESEARCH

TREM2 sustains microglial expansion during aging and response to demyelination

(2015) Pietro Luigi Poliani et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-Like Receptors and Dectin-1, a C-Type Lectin Receptor, Trigger Divergent Functions in CNS Macrophages

(2015) J. C. Gensel et al.   JOURNAL OF NEUROSCIENCE

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury

(2015) F. H. Brennan et al.   JOURNAL OF NEUROSCIENCE

Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype

(2015) Anita C. Thomas et al.   PLoS One

Complement and spinal cord injury: Traditional and non-traditional aspects of complement cascade function in the injured spinal cord microenvironment

(2014) Sheri L. Peterson et al.   EXPERIMENTAL NEUROLOGY

Macrophages in spinal cord injury: Phenotypic and functional change from exposure to myelin debris

(2014) Xi Wang et al.   GLIA

Differences in the Phagocytic Response of Microglia and Peripheral Macrophages after Spinal Cord Injury and Its Effects on Cell Death

(2014) A. D. Greenhalgh et al.   JOURNAL OF NEUROSCIENCE

In vivo longitudinal Myelin Water Imaging in rat spinal cord following dorsal column transection injury

(2014) Piotr Kozlowski et al.   MAGNETIC RESONANCE IMAGING

Function of microglia and macrophages in secondary damage after spinal cord injury

(2014) Yi Ren et al.   Neural Regeneration Research

TNF and Increased Intracellular Iron Alter Macrophage Polarization to a Detrimental M1 Phenotype in the Injured Spinal Cord

(2014) Antje Kroner et al.   NEURON

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

Myelin alters the inflammatory phenotype of macrophages by activating PPARs

(2013) Jeroen FJ Bogie et al.   Acta Neuropathologica Communications

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Pathological Changes in the White Matter after Spinal Contusion Injury in the Rat

(2012) C. Joakim Ek et al.   PLoS One

Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation

(2012) Jeroen F. J. Bogie et al.   PLoS One

Specific lipid recognition is a general feature of CD300 and TREM molecules

(2011) John P. Cannon et al.   IMMUNOGENETICS

Antioxidant Therapies for Acute Spinal Cord Injury

(2011) Edward D. Hall   Neurotherapeutics

Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment

(2010) Kevin D. Beck et al.   BRAIN

Myelin Activates FAK/Akt/NF-κB Pathways and Provokes CR3-Dependent Inflammatory Response in Murine System

(2010) Xin Sun et al.   PLoS One

The Role of Galectin-3/MAC-2 in the Activation of the Innate-Immune Function of Phagocytosis in Microglia in Injury and Disease

(2009) Shlomo Rotshenker   JOURNAL OF MOLECULAR NEUROSCIENCE

Temporospatial Expression and Cellular Localization of Oligodendrocyte Myelin Glycoprotein (OMgp) after Traumatic Spinal Cord Injury in Adult Rats

(2009) Fangfang Dou et al.   JOURNAL OF NEUROTRAUMA

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: Quantification of migration by a novel near-infrared method

(2008) Aaron M. Miller et al.   GLIA

The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges: TABLE 1.

(2008) David R. Greaves et al.   JOURNAL OF LIPID RESEARCH

Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury

(2008) Hal X Nguyen et al.   Journal of Neuroinflammation

Deficiency in Complement C1q Improves Histological and Functional Locomotor Outcome after Spinal Cord Injury

(2008) M. D. Galvan et al.   JOURNAL OF NEUROSCIENCE

Efficient colonic mucosal wound repair requires Trem2 signaling

(2008) H. Seno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA