RS9, a novel Nrf2 activator, attenuates light-induced death of cells of photoreceptor cells and Müller glia cells

Protective effects of NSP-116, a novel imidazolyl aniline derivative, against light-induced retinal damage in vitro and in vivo

(2016) Hiroshi Izawa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Cε/Nrf2/HO-1 Pathway

(2016) Chao Guo et al.   MOLECULAR NEUROBIOLOGY

Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under warfarin anticoagulation

(2016) Takahiko Imai et al.   NEUROBIOLOGY OF DISEASE

A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice

(2016) Keita Yamauchi et al.   NEUROSCIENCE

EGFR mediates astragaloside IV-induced Nrf2 activation to protect cortical neurons against in vitro ischemia/reperfusion damages

(2015) Da-min Gu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel Nrf2 activators from microbial transformation products inhibit blood-retinal barrier permeability in rabbits

(2015) Yasuhiro Nakagami et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy supports survival and phototransduction protein levels in rod photoreceptors

(2015) Z Zhou et al.   CELL DEATH AND DIFFERENTIATION

Ebselen by modulating oxidative stress improves hypoxia-induced macroglial Müller cell and vascular injury in the retina

(2015) Sih Min Tan et al.   EXPERIMENTAL EYE RESEARCH

Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc−, the Na+-independent glutamate–cystine exchanger

(2015) Jing Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage

(2015) Wenjun Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A

(2015) Yanhong Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotection by rat Müller glia against high glucose-induced neurodegeneration through a mechanism involving ERK1/2 activation

(2014) Andrea Matteucci et al.   EXPERIMENTAL EYE RESEARCH

Hydroxyl radicals cause fluctuation in intracellular ferrous ion levels upon light exposure during photoreceptor cell death

(2014) Tomoyo Imamura et al.   EXPERIMENTAL EYE RESEARCH

Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia–reperfusion injury

(2014) Toshinori Takagi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Astaxanthin Activates Nuclear Factor Erythroid-Related Factor 2 and the Antioxidant Responsive Element (Nrf2-ARE) Pathway in the Brain after Subarachnoid Hemorrhage in Rats and Attenuates Early Brain Injury

(2014) Qi Wu et al.   Marine Drugs

Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light

(2014) Yoshiki Kuse et al.   Scientific Reports

Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death

(2013) Noriko Himori et al.   JOURNAL OF NEUROCHEMISTRY

CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Muller glial cells

(2013) K. D. Rhee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis

(2012) Kalavathi Dasuri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice

(2012) Tomohiro Nakanishi et al.   JOURNAL OF NEUROCHEMISTRY

Hydrogen Sulfide Protects the Retina from Light-induced Degeneration by the Modulation of Ca2+Influx

(2011) Yoshinori Mikami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 Expression by Neurons, Astroglia, and Microglia in the Cerebral Cortical Penumbra of Ischemic Rats

(2011) Jon Dang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Age-Related Retinopathy in NRF2-Deficient Mice

(2011) Zhenyang Zhao et al.   PLoS One

Systemic administration of a free radical scavenger, edaravone, protects against light-induced photoreceptor degeneration in the mouse retina

(2010) Shunsuke Imai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Oxidation and age-related macular degeneration: insights from molecular biology

(2010) Sam Khandhadia et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease

(2010) G. P. Sykiotis et al.   Science Signaling

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE