Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation

Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays

(2015) Adam S. Olia et al.   ACS Chemical Biology

The ɛ-Amino Group of Protein Lysine Residues Is Highly Susceptible to Nonenzymatic Acylation by Several Physiological Acyl-CoA Thioesters

(2015) Zeljko Simic et al.   CHEMBIOCHEM

Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

(2015) Lei Shi et al.   CURRENT OPINION IN CELL BIOLOGY

Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism

(2015) Benjamin D. Rowlands et al.   JOURNAL OF NEUROSCIENCE RESEARCH

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(2014) Bixi Jian et al.   MOLECULAR MEDICINE

Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+and SRT1720: binding details and inhibition mechanism

(2013) Giang Thi Tuyet Nguyen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Glutamate Metabolism is Impaired in Transgenic Mice with Tau Hyperphosphorylation

(2013) Linn Hege Nilsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In vivoquantification of neuro-glial metabolism and glial glutamate concentration using1H-[13C] MRS at 14.1T

(2013) Bernard Lanz et al.   JOURNAL OF NEUROCHEMISTRY

Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA(A) receptors and has measureable metabolic effects at very low concentrations

(2013) Caroline D. Rae et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of human glutamine synthetase by L-methionine-S,R-sulfoximine—relevance to the treatment of neurological diseases

(2013) Thomas M. Jeitner et al.   METABOLIC BRAIN DISEASE

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators

(2013) B. P. Hubbard et al.   SCIENCE

SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: Implications for cell survival after irradiation

(2012) Hyun-Yoo Joo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deciphering a global network of functionally associated post-translational modifications

(2012) Pablo Minguez et al.   Molecular Systems Biology

Metabolism, Compartmentation, Transport and Production of Acetate in the Cortical Brain Tissue Slice

(2012) Caroline Rae et al.   NEUROCHEMICAL RESEARCH

Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation

(2011) William C. Hallows et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate

(2011) E Babu et al.   ONCOGENE

Distribution Analysis of Deacetylase SIRT1 in Rodent and Human Nervous Systems

(2010) Sherry M. Zakhary et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

(2010) Michelle Pacholec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of Cerebral Acetate Transport and Metabolic Rates in the Rat Brain in vivo Using 1H-[13C]-NMR

(2010) Anant B Patel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Nuclear-cytoplasmic localization of acetyl coenzyme a synthetase-1 in the rat brain

(2010) Prasanth S. Ariyannur et al.   JOURNAL OF COMPARATIVE NEUROLOGY

γ-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB

(2010) Fatima A. Nasrallah et al.   JOURNAL OF NEUROCHEMISTRY

Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy

(2009) Fawzi Boumezbeur et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Exchange-mediated dilution of brain lactate specific activity: implications for the origin of glutamate dilution and the contributions of glutamine dilution and other pathways

(2009) Gerald A. Dienel et al.   JOURNAL OF NEUROCHEMISTRY

Acetate transport and utilization in the rat brain

(2009) Dinesh K. Deelchand et al.   JOURNAL OF NEUROCHEMISTRY

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Simultaneous measurement of neuronal and glial metabolism in rat brain in vivo using co-infusion of [1,6-13C2]glucose and [1,2-13C2]acetate

(2008) Dinesh K. Deelchand et al.   JOURNAL OF MAGNETIC RESONANCE

Brain SIRT1: Anatomical Distribution and Regulation by Energy Availability

(2008) G. Ramadori et al.   JOURNAL OF NEUROSCIENCE

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

(2008) S. Hisahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nampt: linking NAD biology, metabolism and cancer

(2008) Antje Garten et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM