Current trends in mouse models of glioblastoma

Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models

(2017) Jian Teng et al.   NEURO-ONCOLOGY

Therapeutic Hypothesis Testing With Rodent Brain Tumor Models

(2017) Derek A. Wainwright et al.   Neurotherapeutics

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis

(2016) Chiara Bardella et al.   CANCER CELL

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance

(2016) Laura Garros-Regulez et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model

(2016) Laura Mercurio et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo

(2016) Emese Szabo et al.   NEURO-ONCOLOGY

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

(2016) Ignacio Sancho-Martinez et al.   Nature Communications

Endogenous Neoantigen-Specific CD8 T Cells Identified in Two Glioblastoma Models Using a Cancer Immunogenomics Approach

(2016) T. M. Johanns et al.   Cancer Immunology Research

A Novel Mouse Model of Diffuse Intrinsic Pontine Glioma Initiated in Pax3-Expressing Cells

(2016) Katherine L. Misuraca et al.   NEOPLASIA

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

(2015) Kensuke Tateishi et al.   CANCER CELL

Dedifferentiation of patient-derived glioblastoma multiforme cell lines results in a cancer stem cell-like state with mitogen-independent growth

(2015) Inan Olmez et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma

(2015) Congcong Zhang et al.   JNCI-Journal of the National Cancer Institute

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System

(2015) K. E. Parrish et al.   MOLECULAR CANCER THERAPEUTICS

The Evidence of Glioblastoma Heterogeneity

(2015) Akio Soeda et al.   Scientific Reports

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma

(2015) Congcong Zhang et al.   JNCI-Journal of the National Cancer Institute

Successful Treatment of Intracranial Glioblastoma Xenografts With a Monoamine Oxidase B-Activated Pro-Drug

(2015) Martyn A. Sharpe et al.   EBioMedicine

Combining Bevacizumab with Temozolomide Increases the Antitumor Efficacy of Temozolomide in a Human Glioblastoma Orthotopic Xenograft Model

(2015) Véronique Mathieu et al.   NEOPLASIA

A Urokinase Receptor-Bim Signaling Axis Emerges during EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma

(2014) J. Wykosky et al.   CANCER RESEARCH

Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment

(2014) E. Garralda et al.   CLINICAL CANCER RESEARCH

Discordant In Vitro and In Vivo Chemopotentiating Effects of the PARP Inhibitor Veliparib in Temozolomide-Sensitive versus -Resistant Glioblastoma Multiforme Xenografts

(2014) S. K. Gupta et al.   CLINICAL CANCER RESEARCH

NT113, a Pan-ERBB Inhibitor with High Brain Penetrance, Inhibits the Growth of Glioblastoma Xenografts with EGFR Amplification

(2014) Y. Yoshida et al.   MOLECULAR CANCER THERAPEUTICS

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

(2014) Rintaro Hashizume et al.   NATURE MEDICINE

Modeling Adult Gliomas Using RCAS/t-va Technology

(2014) Dolores Hambardzumyan et al.   Translational Oncology

Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma

(2014) Katherine L. Misuraca et al.   Acta Neuropathologica Communications

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma

(2013) TADASHI ASHIZAWA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas

(2013) Jing Zeng et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Glial Promoter Selectivity following AAV-Delivery to the Immature Brain

(2013) Georg von Jonquieres et al.   PLoS One

Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ

(2013) Kyeung Min Joo et al.   Cell Reports

The Definition of Primary and Secondary Glioblastoma

(2012) H. Ohgaki et al.   CLINICAL CANCER RESEARCH

Genome interpreter vies for place in clinical market

(2012) Monya Baker   NATURE

Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

(2012) D. Singh et al.   SCIENCE

Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies

(2011) J. Cho et al.   CANCER RESEARCH

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway

(2011) Mayumi Jijiwa et al.   PLoS One

A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

(2011) J. D. Kessler et al.   SCIENCE

Frequent abnormalities of the immune system in gliomas and correlation with the WHO grading system of malignancy

(2010) K. Gousias et al.   JOURNAL OF NEUROIMMUNOLOGY

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

(2009) Sheila Alcantara Llaguno et al.   CANCER CELL

Development of a novel mouse glioma model using lentiviral vectors

(2009) Tomotoshi Marumoto et al.   NATURE MEDICINE

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis

(2009) Haihao Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma

(2008) Qin Shu et al.   STEM CELLS