Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

ALDH1B1 links alcohol consumption and diabetes

(2015) Surendra Singh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

(2015) D Grahame Hardie   CURRENT OPINION IN CELL BIOLOGY

Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program

(2014) Tao Gao et al.   Cell Metabolism

Decreasing Cx36 Gap Junction Coupling Compensates for Overactive KATPChannels to Restore Insulin Secretion and Prevent Hyperglycemia in a Mouse Model of Neonatal Diabetes

(2014) Linda M. Nguyen et al.   DIABETES

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

(2014) Yan Hang et al.   DIABETES

Maternal Protein Restriction Leads to Pancreatic Failure in Offspring: Role of Misexpressed MicroRNA-375

(2014) O. Dumortier et al.   DIABETES

Gene Regulatory Networks Governing Pancreas Development

(2013) H. Efsun Arda et al.   DEVELOPMENTAL CELL

Nrf2 Protects Pancreatic  -Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice

(2013) Y. Yagishita et al.   DIABETES

Quantification of excess risk for diabetes for those born in times of hunger, in an entire population of a nation, across a century

(2013) S. Thurner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery

(2013) F. Guenard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3

(2013) P. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

(2013) Brandon L. Taylor et al.   Cell Reports

Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

(2013) Ashleigh E. Schaffer et al.   PLoS Genetics

Metabolic Regulation of Epigenetics

(2012) Chao Lu et al.   Cell Metabolism

ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools

(2012) Marilia Ioannou et al.   DEVELOPMENTAL BIOLOGY

Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

(2012) William R. Goodyer et al.   DEVELOPMENTAL CELL

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes

(2012) T. M. Reinbothe et al.   DIABETOLOGIA

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

(2012) Juan I. Garaycoechea et al.   NATURE

Progenitor cell domains in the developing and adult pancreas

(2011) Janel L. Kopp et al.   CELL CYCLE

G Protein-Coupled Receptor Signaling and Sphingosine-1-Phosphate Play a Phylogenetically Conserved Role in Endocrine Pancreas Morphogenesis

(2011) I. Serafimidis et al.   MOLECULAR AND CELLULAR BIOLOGY

Concise Review: Aldehyde Dehydrogenase Bright Stem and Progenitor Cell Populations from Normal Tissues: Characteristics, Activities, and Emerging Uses in Regenerative Medicine

(2011) Andrew E. Balber   STEM CELLS

Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity

(2010) Chunyan Gu et al.   Cell Metabolism

The Stunned β Cell: A Brief History

(2010) Ele Ferrannini   Cell Metabolism

The insulin secretory granule as a signaling hub

(2010) Jakob Suckale et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cdc42-Mediated Tubulogenesis Controls Cell Specification

(2009) Gokul Kesavan et al.   CELL

MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities

(2009) C. V. Dang et al.   CLINICAL CANCER RESEARCH

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

(2009) A. Du et al.   DIABETES

Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin

(2009) Simon C Lee et al.   JOURNAL OF ENDOCRINOLOGY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

(2009) M. Rovira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY