LKB1 couples glucose metabolism to insulin secretion in mice

LKB1 and AMPK differentially regulate pancreatic β-cell identity

(2014) Marina Kone et al.   FASEB JOURNAL

Role of the SIK2–p35–PJA2 complex in pancreatic β-cell functional compensation

(2014) Jun-Ichi Sakamaki et al.   NATURE CELL BIOLOGY

ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics

(2014) M. Norton et al.   Science Signaling

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

(2014) Ghupurjan Gheni et al.   Cell Reports

UCP2 Regulates the Glucagon Response to Fasting and Starvation

(2013) E. M. Allister et al.   DIABETES

Cephalic phase insulin secretion is KATP channel independent

(2013) Yusuke Seino et al.   JOURNAL OF ENDOCRINOLOGY

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling

(2013) Jia Nie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose-stimulated insulin secretion: A newer perspective

(2013) Mitsuhisa Komatsu et al.   Journal of Diabetes Investigation

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

(2012) Brandon Faubert et al.   Cell Metabolism

Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic  -Cells Leads to Relative Hyperinsulinism During Exercise

(2012) T. J. Pullen et al.   DIABETES

Quantitative imaging of electron transfer flavoprotein autofluorescence reveals the dynamics of lipid partitioning in living pancreatic islets

(2012) Alan K. Lam et al.   Integrative Biology

Brain-selective Kinase 2 (BRSK2) Phosphorylation on PCTAIRE1 Negatively Regulates Glucose-stimulated Insulin Secretion in Pancreatic β-Cells

(2012) Xin-Ya Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Second-phase insulin secretion gets cool

(2011) Robert G. Tsushima   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells

(2011) Nicole Feldmann et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo

(2010) Gao Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4

(2010) Jenna L. Jewell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Voltage-dependent K+ channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans

(2010) A. F. Spigelman et al.   DIABETOLOGIA

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

(2010) Sushma Gurumurthy et al.   NATURE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

LKB1 Regulates Pancreatic β Cell Size, Polarity, and Function

(2009) Zvi Granot et al.   Cell Metabolism

Loss of Lkb1 in Adult β Cells Increases β Cell Mass and Enhances Glucose Tolerance in Mice

(2009) Accalia Fu et al.   Cell Metabolism

Sulfonylurea Receptor 1 Mutations That Cause Opposite Insulin Secretion Defects with Chemical Chaperone Exposure

(2009) Emily B. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Suppression of Acetyl-CoA Carboxylase 1 in β-Cells Impairs Insulin Secretion via Inhibition of Glucose Rather Than Lipid Metabolism

(2008) Sarah M. Ronnebaum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator

(2008) J. Aittoniemi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES