Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

Title
Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 60, Issue 24, Pages 9960-9973
Publisher
American Chemical Society (ACS)
Online
2017-11-17
DOI
10.1021/acs.jmedchem.7b00907

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