microRNA-30c reduces plasma cholesterol in homozygous familial hypercholesterolemic and type 2 diabetic mouse models

MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice

(2016) Sara Irani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of proprotein convertase subtilisin-kexin type 9 serine protease inhibitors on lipid levels and outcomes in patients with primary hypercholesterolaemia: a network meta-analysis

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Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial

(2015) Frederick J Raal et al.   LANCET

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(2014) Zahid Ahmad   AMERICAN JOURNAL OF CARDIOLOGY

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(2014) Daniel J. Rader et al.   CIRCULATION

Impaired Cholesterol Metabolism and Enhanced Atherosclerosis in Clock Mutant Mice

(2013) Xiaoyue Pan et al.   CIRCULATION

Microsomal transfer protein inhibition in humans

(2013) Marina Cuchel et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Increased Intestinal Lipid Absorption Caused by Ire1β Deficiency Contributes to Hyperlipidemia and Atherosclerosis in Apolipoprotein E–Deficient Mice

(2012) Jahangir Iqbal et al.   CIRCULATION RESEARCH

The PCSK9 decade

(2012) Gilles Lambert et al.   JOURNAL OF LIPID RESEARCH

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

(2012) Marina Cuchel et al.   LANCET

Multiple functions of microsomal triglyceride transfer protein

(2012) M Mahmood Hussain et al.   Nutrition & Metabolism

New Lipid Modulating Drugs: The Role of Microsomal Transport Protein Inhibitors

(2011) Manfredi Rizzo et al.   CURRENT PHARMACEUTICAL DESIGN

Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice

(2011) Irani Khatun et al.   HEPATOLOGY

Animal Models of Cardiovascular Diseases

(2011) Carlos Zaragoza et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response

(2008) Deepak Voora et al.   Circulation-Cardiovascular Genetics

New approaches to target microsomal triglyceride transfer protein

(2008) Mohammed Mahmood Hussain et al.   CURRENT OPINION IN LIPIDOLOGY

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

(2008) Frederick F Samaha et al.   Nature clinical practice. Cardiovascular medicine

Microsomal triglyceride transfer protein inhibition–friend or foe?

(2008) Tisha R Joy et al.   Nature clinical practice. Cardiovascular medicine