Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis

Akkermansia MuciniphilaProtects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation inApoe−/−MiceCLINICAL PERSPECTIVE

(2016) Jin Li et al.   CIRCULATION

Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E Deficient Mice

(2016) Vishal Singh et al.   INFLAMMATORY BOWEL DISEASES

Interaction between dietary lipids and gut microbiota regulates hepatic cholesterol metabolism

(2016) Robert Caesar et al.   JOURNAL OF LIPID RESEARCH

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho

(2016) Ting Fu et al.   MOLECULAR ENDOCRINOLOGY

Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice

(2016) Ida Rune et al.   PLoS One

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

(2014) Changtao Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS

(2014) Genta Kakiyama et al.   JOURNAL OF LIPID RESEARCH

CD3 Antibody and IL‐2 Complex Combination Therapy Inhibits Atherosclerosis by Augmenting a Regulatory Immune Response

(2014) Kazuyuki Kasahara et al.   Journal of the American Heart Association

Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice

(2013) Tian Lan et al.   ATHEROSCLEROSIS

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Lactobacillus acidophilus ATCC 4356 attenuates the atherosclerotic progression through modulation of oxidative stress and inflammatory process

(2013) Lihua Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet

(2011) Renata Stepankova et al.   Journal of Atherosclerosis and Thrombosis

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

(2010) Tiangang Li et al.   HEPATOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Bile acid transporters

(2009) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

The gut microbiota modulates host energy and lipid metabolism in mice

(2009) Vidya R. Velagapudi et al.   JOURNAL OF LIPID RESEARCH

Gut microbiota and lipopolysaccharide content of the diet influence development of regulatory T cells: studies in germ-free mice

(2008) Tomas Hrncir et al.   BMC IMMUNOLOGY

Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21

(2008) Takeshi Inagaki et al.   Cell Metabolism

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES