Deletion of BCG Hip1 protease enhances dendritic cell and CD4 T cell responses

Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice

(2017) Mushtaq Ahmed et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection

(2017) Jonathan Kevin Sia et al.   PLoS Pathogens

Recombinant Mycobacterium bovis bacillus Calmette–Guérin expressing Ag85B-IL-7 fusion protein enhances IL-17A-producing innate γδ T cells

(2016) Shinya Hatano et al.   VACCINE

Deletion of nuoG from the Vaccine Candidate Mycobacterium bovis BCG Δ ureC :: hly Improves Protection against Tuberculosis

(2016) Martin Gengenbacher et al.   mBio

Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

(2016) Carolina Perdomo et al.   mBio

Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy

(2016) Kristin L. Griffiths et al.   Nature Communications

Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial

(2016) Daniel F. Hoft et al.   EBioMedicine

Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity

(2015) Patrick R. Burkett et al.   JOURNAL OF CLINICAL INVESTIGATION

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17–Dependent Mechanism

(2015) Nacho Aguilo et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions

(2015) Marilena P. Etna et al.   Scientific Reports

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions betweenMycobacterium tuberculosisand Innate Immune Cells

(2015) Jonathan Kevin Sia et al.   Journal of Immunology Research

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming

(2014) Smita Srivastava et al.   Cell Host & Microbe

Pulmonary Mycobacterium bovis BCG Vaccination Confers Dose-Dependent Superior Protection Compared to That of Subcutaneous Vaccination

(2014) Nacho Aguilo et al.   Clinical and Vaccine Immunology

Mycobacterium tuberculosis Impairs Dendritic Cell Functions through the Serine Hydrolase Hip1

(2014) R. Madan-Lala et al.   JOURNAL OF IMMUNOLOGY

Central Memory CD4+ T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis

(2014) Alexis Vogelzang et al.   JOURNAL OF INFECTIOUS DISEASES

The Recombinant BCG ΔureC::hlyVaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation

(2014) Hiroyuki Saiga et al.   JOURNAL OF INFECTIOUS DISEASES

The Glycosylated Rv1860 Protein of Mycobacterium tuberculosis Inhibits Dendritic Cell Mediated TH1 and TH17 Polarization of T Cells and Abrogates Protective Immunity Conferred by BCG

(2014) Vijaya Satchidanandam et al.   PLoS Pathogens

Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials

(2013) Punam Mangtani et al.   CLINICAL INFECTIOUS DISEASES

The Tuberculosis Vaccine Candidate Bacillus Calmette-Guérin ΔureC::hly Coexpressing Human Interleukin-7 or -18 Enhances Antigen-Specific T Cell Responses in Mice

(2013) Martin Rao et al.   PLoS One

Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells

(2012) H Dong et al.   Mucosal Immunology

The recombinant tuberculosis vaccine rBCG ΔureC::hly+ induces apoptotic vesicles for improved priming of CD4+ and CD8+ T cells

(2012) Maura Farinacci et al.   VACCINE

A novel recombinant Mycobacterium bovis bacillus Calmette-Guerin strain expressing human granulocyte macrophage colony-stimulating factor and Mycobacterium tuberculosis early secretory antigenic target 6 complex augments Th1 immunity

(2011) X. Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Relief from Zmp1-Mediated Arrest of Phagosome Maturation Is Associated with Facilitated Presentation and Enhanced Immunogenicity of Mycobacterial Antigens

(2011) Pål Johansen et al.   Clinical and Vaccine Immunology

Recombinant BCG ΔureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses

(2011) Christiane Desel et al.   JOURNAL OF INFECTIOUS DISEASES

A multistage tuberculosis vaccine that confers efficient protection before and after exposure

(2011) Claus Aagaard et al.   NATURE MEDICINE

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Dendritic Cells in Chronic Mycobacterial Granulomas Restrict Local Anti-Bacterial T Cell Response in a Murine Model

(2010) Heidi A. Schreiber et al.   PLoS One

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

(2009) Chinnaswamy Jagannath et al.   NATURE MEDICINE

A Liposome-Based Mycobacterial Vaccine Induces Potent Adult and Neonatal Multifunctional T Cells through the Exquisite Targeting of Dendritic Cells

(2009) Arun T. Kamath et al.   PLoS One

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe