IL-21 Receptor Signaling Is Essential for Optimal CD4+T Cell Function and Control ofMycobacterium tuberculosisInfection in Mice

IL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosis

(2016) S Venkatasubramanian et al.   Mucosal Immunology

IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection

(2016) Matthew G. Booty et al.   Scientific Reports

Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12

(2016) Li Li et al.   PLoS One

Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge

(2015) L Monin et al.   Mucosal Immunology

Antigen-specific human NKT cells from tuberculosis patients produce IL-21 to help B cells for the production of immunoglobulins

(2015) Changyou Wu et al.   Oncotarget

A Rho GDP Dissociation Inhibitor Produced by Apoptotic T-Cells Inhibits Growth of Mycobacterium tuberculosis

(2015) Sambasivan Venkatasubramanian et al.   PLoS Pathogens

Human CD8+ T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Represent a Novel Human T-cell Subset

(2015) Krista E. van Meijgaarden et al.   PLoS Pathogens

T-bet Regulates Immunity to Francisella tularensis Live Vaccine Strain Infection, Particularly in Lungs

(2014) Amanda A. Melillo et al.   INFECTION AND IMMUNITY

Decreased Frequencies of Circulating CD4+ T Follicular Helper Cells Associated with Diminished Plasma IL-21 in Active Pulmonary Tuberculosis

(2014) Nathella Pavan Kumar et al.   PLoS One

T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection

(2014) Marcus Buggert et al.   PLoS Pathogens

Characterization of T-Bet and Eomes in Peripheral Human Immune Cells

(2014) James J. Knox et al.   Frontiers in Immunology

T cell responses: naïve to memory and everything in between

(2013) Nathan D. Pennock et al.   ADVANCES IN PHYSIOLOGY EDUCATION

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

CXCR5+ T helper cells mediate protective immunity against tuberculosis

(2013) Samantha R. Slight et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations

(2013) L. M. McLane et al.   JOURNAL OF IMMUNOLOGY

IL-21-Producing Th Cells in Immunity and Autoimmunity

(2013) S. M. Liu et al.   JOURNAL OF IMMUNOLOGY

Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses

(2013) R. M. B. Teles et al.   SCIENCE

IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection

(2013) Iwana Schmitz et al.   PLoS Pathogens

Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors

(2012) P. Ribeiro-dos-Santos et al.   BLOOD

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Maintenance of Peripheral T Cell Responses during Mycobacterium tuberculosis Infection

(2012) William W. Reiley et al.   JOURNAL OF IMMUNOLOGY

Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

(2012) M. A. Paley et al.   SCIENCE

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Inflammatory cytokines as a third signal for T cell activation

(2010) Julie M Curtsinger et al.   CURRENT OPINION IN IMMUNOLOGY

The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

(2010) Rajesh R. Rao et al.   IMMUNITY

Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection

(2010) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

Cellular and molecular mechanisms of memory T-cell survival

(2009) Andre Tanel et al.   Expert Review of Vaccines

A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection

(2009) J. S. Yi et al.   SCIENCE

IL-21 Is Required to Control Chronic Viral Infection

(2009) H. Elsaesser et al.   SCIENCE

IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection

(2009) A. Frohlich et al.   SCIENCE

Comparison of Immune Responses Induced in Mice by Vaccination with DNA Vaccine Constructs Expressing Mycobacterial Antigen 85A and Interleukin-21 and Bacillus Galmette-Guérin

(2008) Jun Dou et al.   IMMUNOLOGICAL INVESTIGATIONS

Distinct regulation of effector and memory T-cell differentiation

(2008) Axel Kallies   IMMUNOLOGY AND CELL BIOLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology