Semaphorin 3E Deficiency Exacerbates Airway Inflammation, Hyperresponsiveness, and Remodeling in a Mouse Model of Allergic Asthma

Semaphorin 4C Protects against Allergic Inflammation: Requirement of Regulatory CD138+Plasma Cells

(2016) Di Xue et al.   JOURNAL OF IMMUNOLOGY

Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial

(2016) J Mark FitzGerald et al.   LANCET

The development and function of lung-resident macrophages and dendritic cells

(2015) Manfred Kopf et al.   NATURE IMMUNOLOGY

The immunology of asthma

(2015) Bart N Lambrecht et al.   NATURE IMMUNOLOGY

IL-17 in Severe Asthma. Where Do We Stand?

(2014) Julie Chesné et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Eosinophils in the pathogenesis of paediatric severe asthma

(2014) Sejal Saglani et al.   Current Opinion in Allergy and Clinical Immunology

Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation

(2014) Nariman A. Balenga et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The cell biology of asthma

(2014) David J. Erle et al.   JOURNAL OF CELL BIOLOGY

IL-17-Producing Alveolar Macrophages Mediate Allergic Lung Inflammation Related to Asthma

(2014) C. Song et al.   JOURNAL OF IMMUNOLOGY

Semaphorins and plexins as therapeutic targets

(2014) Thomas Worzfeld et al.   NATURE REVIEWS DRUG DISCOVERY

Neuroimmune Guidance Cue Semaphorin 3E Is Expressed in Atherosclerotic Plaques and Regulates Macrophage Retention

(2013) Amarylis Wanschel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Semaphorin3E-Induced Inflammation Contributes to Insulin Resistance in Dietary Obesity

(2013) Ippei Shimizu et al.   Cell Metabolism

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

Neuronal chemorepellent Semaphorin 3E inhibits human airway smooth muscle cell proliferation and migration

(2013) Hesam Movassagh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cutting Edge: Inhaled Antigen Upregulates Retinaldehyde Dehydrogenase in Lung CD103+ but Not Plasmacytoid Dendritic Cells To Induce Foxp3 De Novo in CD4+ T Cells and Promote Airway Tolerance

(2013) A. Khare et al.   JOURNAL OF IMMUNOLOGY

The miR-126–VEGFR2 axis controls the innate response to pathogen-associated nucleic acids

(2013) Judith Agudo et al.   NATURE IMMUNOLOGY

Linoleic acid metabolite drives severe asthma by causing airway epithelial injury

(2013) Ulaganathan Mabalirajan et al.   Scientific Reports

Integrin Activation States and Eosinophil Recruitment in Asthma

(2013) Mats W. Johansson et al.   Frontiers in Pharmacology

An Inhibitory Role for Sema4A in Antigen-Specific Allergic Asthma

(2012) Tetsuo Morihana et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Alternaria Induces STAT6-Dependent Acute Airway Eosinophilia and Epithelial FIZZ1 Expression That Promotes Airway Fibrosis and Epithelial Thickness

(2012) T. A. Doherty et al.   JOURNAL OF IMMUNOLOGY

Neuroimmune semaphorin 4A downregulates the severity of allergic response

(2012) E H Nkyimbeng-Takwi et al.   Mucosal Immunology

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production

(2012) Eda K. Holl et al.   PLoS One

Chlamydia muridarum Lung Infection in Infants Alters Hematopoietic Cells to Promote Allergic Airway Disease in Mice

(2012) Malcolm R. Starkey et al.   PLoS One

Semaphorin-3D and Semaphorin-3E Inhibit the Development of Tumors from Glioblastoma Cells Implanted in the Cortex of the Brain

(2012) Adi D. Sabag et al.   PLoS One

Airway Hyperresponsiveness: New Insights into the Pathogenesis

(2012) Marek Lommatzsch   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Mouse Lung CD103+and CD11bhighDendritic Cells Preferentially Induce Distinct CD4+T-Cell Responses

(2011) Kazuki Furuhashi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Eosinophils Are Dispensable for Allergic Remodeling and Immunity in a Model of House Dust Mite–induced Airway Disease

(2010) Ramzi Fattouh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of interleukin-4Rα in the induction of glutamic acid decarboxylase in airway epithelium following acute house dust mite exposure

(2010) J. A. Hirota et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A new look at the pathogenesis of asthma

(2010) Stephen T. Holgate et al.   CLINICAL SCIENCE

The many paths to asthma: phenotype shaped by innate and adaptive immunity

(2010) Hye Young Kim et al.   NATURE IMMUNOLOGY

Inhibition of Semaphorin As a Novel Strategy for Therapeutic Angiogenesis

(2009) Junji Moriya et al.   CIRCULATION RESEARCH

Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation

(2009) Svetlana P. Chapoval et al.   CLINICAL IMMUNOLOGY

Biology of Lung Dendritic Cells at the Origin of Asthma

(2009) Bart N. Lambrecht et al.   IMMUNITY

TH17-associated cytokines (IL-17A and IL-17F) in severe asthma

(2009) Wisam Al-Ramli et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla

(2008) Young I. Choi et al.   IMMUNITY