Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets

(2016) J. W. Rowley et al.   BLOOD

IL-6 Mediates the Intestinal Microvascular Thrombosis Associated with Experimental Colitis

(2016) Hideaki Hozumi et al.   INFLAMMATORY BOWEL DISEASES

Pathogenesis, Diagnosis, and Treatment of Venous Thromboembolism in Older Adults

(2016) Stacy A. Johnson et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Non-genomic activities of retinoic acid receptor alpha control actin cytoskeletal events in human platelets

(2016) M. T. Rondina et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases

(2016) Elizabeth A. Middleton et al.   PHYSIOLOGICAL REVIEWS

Platelet-Monocyte Aggregates and C-Reactive Protein are Associated with VTE in Older Surgical Patients

(2016) Lauren Shih et al.   Scientific Reports

Age-associated changes in long-chain fatty acid profile during healthy aging promote pro-inflammatory monocyte polarization via PPARγ

(2015) Chathyan Pararasa et al.   AGING CELL

Interleukin-6 mediates enhanced thrombus development in cerebral arterioles following a brief period of focal brain ischemia

(2015) Ya Hui Tang et al.   EXPERIMENTAL NEUROLOGY

Granzymes Regulate Proinflammatory Cytokine Responses

(2015) Annette C. Wensink et al.   JOURNAL OF IMMUNOLOGY

Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults

(2015) Rebeca Sara de Pablo-Bernal et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Inflammasome in Platelets: Allying Coagulation and Inflammation in Infectious and Sterile Diseases?

(2015) Eugenio D. Hottz et al.   MEDIATORS OF INFLAMMATION

Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia

(2015) Leila Noetzli et al.   NATURE GENETICS

Platelets in Inflammatory Disorders: A Pathophysiological and Clinical Perspective

(2015) Jecko Thachil   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics

(2014) L. M. Simon et al.   BLOOD

Alterations in Platelet Function During Aging: Clinical Correlations with Thromboinflammatory Disease in Older Adults

(2014) Donya Mohebali et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Platelets in inflammation and immunity

(2014) J. M. Herter et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet-Monocyte Aggregate Formation and Mortality Risk in Older Patients With Severe Sepsis and Septic Shock

(2014) M. T. Rondina et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Granzyme A Produces Bioactive IL-1β through a Nonapoptotic Inflammasome-Independent Pathway

(2014) Dagmar Hildebrand et al.   Cell Reports

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

(2013) E. D. Hottz et al.   BLOOD

Platelets as Cellular Effectors of Inflammation in Vascular Diseases

(2013) Matthew T. Rondina et al.   CIRCULATION RESEARCH

Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration

(2013) Adriana Vieira de Abreu et al.   THROMBOSIS AND HAEMOSTASIS

In Vivo Platelet Activation in Critically Ill Patients With Primary 2009 Influenza A(H1N1)

(2012) Matthew T. Rondina et al.   CHEST

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

The septic milieu triggers expression of spliced tissue factor mRNA in human platelets

(2011) M. T. RONDINA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mutations in NBEAL2, encoding a BEACH protein, cause gray platelet syndrome

(2011) Walter HA Kahr et al.   NATURE GENETICS

Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques

(2011) Matthew T. Rondina et al.   THROMBOSIS RESEARCH

Granzymes in cancer and immunity

(2010) S P Cullen et al.   CELL DEATH AND DIFFERENTIATION

A Role for Granzyme M in TLR4-Driven Inflammation and Endotoxicosis

(2010) D. A. Anthony et al.   JOURNAL OF IMMUNOLOGY

Aging is associated with greater nuclear NFκB, reduced IκBα, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans

(2008) Anthony J. Donato et al.   AGING CELL

Human and Mouse Granzyme A Induce a Proinflammatory Cytokine Response

(2008) Sunil S. Metkar et al.   IMMUNITY